hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_04568.1
Complex Portal: CPX-11339
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| PCDHB9 | Protocadherin beta-9 (PCDH-beta-9) (Protocadherin-3H) | 4 | UniProt NCBI |
| PCDHB8 | Protocadherin beta-8 (PCDH-beta-8) (Protocadherin-3I) | 4 | UniProt NCBI |
| PCDHB3 | Protocadherin beta-3 (PCDH-beta-3) | 4 | UniProt NCBI |
| PCDHB5 | Protocadherin beta-5 (PCDH-beta-5) | 4 | UniProt NCBI |
| PCDHB10 | Protocadherin beta-10 (PCDH-beta-10) | 4 | UniProt NCBI |
| C2CD2L | Phospholipid transfer protein C2CD2L (C2 domain-containing protein 2-like) (C2CD2-like) (Transmembrane protein 24) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0016339 | 1.60994442835e-05 | 0.666666666667 | PCDHB9 PCDHB5 PCDHB10 PCDHB3 | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules |
| GO:0007416 | 0.00129796765781 | 0.666666666667 | PCDHB9 PCDHB5 PCDHB10 PCDHB3 | synapse assembly |
| GO:0098742 | 0.00331023080209 | 0.666666666667 | PCDHB9 PCDHB5 PCDHB10 PCDHB3 | cell-cell adhesion via plasma-membrane adhesion molecules |
| GO:0050808 | 0.0372717918379 | 0.666666666667 | PCDHB9 PCDHB5 PCDHB10 PCDHB3 | synapse organization |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| PCDHB8 | PCDHB3 | 1.0 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| PCDHB3 | PCDHB10 | 1.0 |
mutually_exclusive (Q9NRJ7)
structurally_consistent (dimer) |
bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| PCDHB5 | PCDHB3 | 1.0 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| PCDHB9 | PCDHB3 | 0.999 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| C2CD2L | PCDHB3 | 0.996 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| PCDHB8 | PCDHB10 | 0.949 |
mutually_exclusive (Q9Y5E6)
|
bioplex3_WMM WMM_only | |
| PCDHB9 | PCDHB10 | 0.949 |
mutually_exclusive (Q9Y5E6)
|
bioplex3_WMM WMM_only | |
| PCDHB5 | PCDHB10 | 0.949 |
mutually_exclusive (Q9Y5E6)
|
bioplex3_WMM WMM_only | |
| PCDHB5 | PCDHB8 | 0.946 | 0.138 |
mutually_exclusive (Q9Y5E6)
|
bioplex3_WMM WMM_only |
| PCDHB9 | PCDHB8 | 0.946 |
mutually_exclusive (Q9Y5E6)
|
bioplex3_WMM WMM_only | |
| PCDHB5 | PCDHB9 | 0.946 |
mutually_exclusive (Q9Y5E6)
|
bioplex3_WMM WMM_only | |
| C2CD2L | PCDHB9 | 0.715 | bioplex3_WMM WMM_only | ||
| C2CD2L | PCDHB8 | 0.715 | 0.102 | bioplex3_WMM WMM_only | |
| C2CD2L | PCDHB5 | 0.631 | 0.05 | bioplex3_WMM WMM_only | |
| C2CD2L | PCDHB10 | 0.588 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes