hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_04571.1
Complex Portal: CPX-14375
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| ELL | RNA polymerase II elongation factor ELL (Eleven-nineteen lysine-rich leukemia protein) | 5 | UniProt NCBI |
| ELL3 | RNA polymerase II elongation factor ELL3 | 5 | UniProt NCBI |
| EAF1 | ELL-associated factor 1 | 5 | UniProt NCBI |
| ICE1 | Little elongation complex subunit 1 (Interactor of little elongator complex ELL subunit 1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6084 | 1.15717477383e-07 | 0.75 | ELL3 ELL EAF1 | AFF4 super elongation complex (SEC) |
| GO:0008023 | 4.69325242995e-06 | 1.0 | ICE1 ELL3 ELL EAF1 | transcription elongation factor complex |
| REAC:R-HSA-6807505 | 8.33911915483e-05 | 0.75 | ELL3 ELL ICE1 | RNA polymerase II transcribes snRNA genes |
| GO:0042795 | 0.000139871762976 | 0.75 | ELL3 ELL ICE1 | snRNA transcription by RNA polymerase II |
| GO:0009301 | 0.000261258639543 | 0.75 | ELL3 ELL ICE1 | snRNA transcription |
| KEGG:03250 | 0.00398305490854 | 0.5 | ELL3 ELL | Viral life cycle - HIV-1 |
| REAC:R-HSA-73857 | 0.00681752083972 | 1.0 | ICE1 ELL3 ELL EAF1 | RNA Polymerase II Transcription |
| GO:0035363 | 0.00842684400117 | 0.5 | ELL ICE1 | histone locus body |
| GO:0016073 | 0.00847564117007 | 0.75 | ELL3 ELL ICE1 | snRNA metabolic process |
| REAC:R-HSA-74160 | 0.0112707156575 | 1.0 | ICE1 ELL3 ELL EAF1 | Gene expression (Transcription) |
| REAC:R-HSA-112382 | 0.0162811003561 | 0.5 | EAF1 ELL | Formation of RNA Pol II elongation complex |
| REAC:R-HSA-75955 | 0.0162811003561 | 0.5 | EAF1 ELL | RNA Polymerase II Transcription Elongation |
| GO:0034243 | 0.0291371139957 | 0.75 | ELL3 ELL EAF1 | regulation of transcription elongation by RNA polymerase II |
| REAC:R-HSA-674695 | 0.0313666733646 | 0.5 | EAF1 ELL | RNA Polymerase II Pre-transcription Events |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| ELL | EAF1 | 1.0 | 0.21 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 fraction | |
| ELL3 | EAF1 | 1.0 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| ELL3 | ICE1 | 0.999 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| EAF1 | ICE1 | 0.999 | 0.214 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| ELL | ICE1 | 0.997 | 0.194 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM WMM_only | |
| ELL | ELL3 | 0.987 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
Related Complexes