hu.MAP 3.0: Complex View

Genename	Protein Name	Uniprot Annotation Score	Links
STK4	Serine/threonine-protein kinase 4 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 1) (MST-1) (STE20-like kinase MST1) (Serine/threonine-protein kinase Krs-2) [Cleaved into: Serine/threonine-protein kinase 4 37kDa subunit (MST1/N); Serine/threonine-protein kinase 4 18kDa subunit (MST1/C)]	5	UniProt NCBI
STK3	Serine/threonine-protein kinase 3 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 2) (MST-2) (STE20-like kinase MST2) (Serine/threonine-protein kinase Krs-1) [Cleaved into: Serine/threonine-protein kinase 3 36kDa subunit (MST2/N); Serine/threonine-protein kinase 3 20kDa subunit (MST2/C)]	5	UniProt NCBI
RASSF6	Ras association domain-containing protein 6	4	UniProt NCBI
RASSF2	Ras association domain-containing protein 2	5	UniProt NCBI

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
KEGG:04392	8.91489558656e-07	0.75	STK3 RASSF2 RASSF6	Hippo signaling pathway - multiple species
CORUM:6716	1.53774525569e-05	0.5	STK4 STK3	DLG5-MST1-MST2 complex
REAC:R-HSA-2028269	0.00175047124894	0.5	STK4 STK3	Signaling by Hippo
WP:WP5087	0.0029183957539	0.75	STK3 RASSF2 RASSF6	Pleural mesothelioma
KEGG:04390	0.02620193588	0.5	STK3 RASSF6	Hippo signaling pathway
CORUM:6403	0.049938562206	0.25	STK4	MST1-SAV1 complex
CORUM:6404	0.049938562206	0.25	STK3	MST2-SAV1 complex

Protein 1	Protein 2	Score	ProteomeHD	Interface Overlap	Evidence
STK4	RASSF2	0.999	0.086	structurally_consistent (dimer)	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 gupta_WMM
STK4	STK3	0.999	0.266	mutually_exclusive (P50749)	hein_WMM bioplex_WMM bioplex3_WMM boldt youn_WMM Malo gupta_WMM fraction boldt_WMM
STK3	RASSF2	0.999	0.108	structurally_consistent (dimer)	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 gupta_WMM
STK4	RASSF6	0.987			bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM
STK3	RASSF6	0.985			bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM