hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_04614.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| CR2 | Complement receptor type 2 (Cr2) (Complement C3d receptor) (Epstein-Barr virus receptor) (EBV receptor) (CD antigen CD21) | 5 | UniProt NCBI |
| LGALS1 | Galectin-1 (Gal-1) (14 kDa laminin-binding protein) (HLBP14) (14 kDa lectin) (Beta-galactoside-binding lectin L-14-I) (Galaptin) (HBL) (HPL) (Lactose-binding lectin 1) (Lectin galactoside-binding soluble 1) (Putative MAPK-activating protein PM12) (S-Lac lectin 1) | 5 | UniProt NCBI |
| NECTIN1 | Nectin-1 (Herpes virus entry mediator C) (Herpesvirus entry mediator C) (HveC) (Herpesvirus Ig-like receptor) (HIgR) (Nectin cell adhesion molecule 1) (Poliovirus receptor-related protein 1) (CD antigen CD111) | 5 | UniProt NCBI |
| ITGA1 | Integrin alpha-1 (CD49 antigen-like family member A) (Laminin and collagen receptor) (VLA-1) (CD antigen CD49a) | 5 | UniProt NCBI |
| IGDCC4 | Immunoglobulin superfamily DCC subclass member 4 (Neighbor of punc e11) (Protein DDM36) (hDDM36) | 4 | UniProt NCBI |
| NAGPA | N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase (EC 3.1.4.45) (Mannose 6-phosphate-uncovering enzyme) (Phosphodiester alpha-GlcNAcase) | 5 | UniProt NCBI |
| CD9 | CD9 antigen (5H9 antigen) (Cell growth-inhibiting gene 2 protein) (Leukocyte antigen MIC3) (Motility-related protein) (MRP-1) (Tetraspanin-29) (Tspan-29) (p24) (CD antigen CD9) | 5 | UniProt NCBI |
| ACE | Angiotensin-converting enzyme (ACE) (EC 3.4.15.1) (Dipeptidyl carboxypeptidase I) (Kininase II) (CD antigen CD143) [Cleaved into: Angiotensin-converting enzyme, soluble form] | 5 | UniProt NCBI |
| PTGFRN | Prostaglandin F2 receptor negative regulator (CD9 partner 1) (CD9P-1) (Glu-Trp-Ile EWI motif-containing protein F) (EWI-F) (Prostaglandin F2-alpha receptor regulatory protein) (Prostaglandin F2-alpha receptor-associated protein) (CD antigen CD315) | 5 | UniProt NCBI |
| MEGF9 | Multiple epidermal growth factor-like domains protein 9 (Multiple EGF-like domains protein 9) (Epidermal growth factor-like protein 5) (EGF-like protein 5) | 4 | UniProt NCBI |
| EFCAB14 | EF-hand calcium-binding domain-containing protein 14 | 2 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04640 | 0.0286338067835 | 0.222222222222 | ITGA1 CD9 | Hematopoietic cell lineage |
| HPA:0500111 | 0.0408271396177 | 0.666666666667 | MEGF9 IGDCC4 LGALS1 PTGFRN CD9 EFCAB14 | soft tissue 1; chondrocytes[>=Low] |
| CORUM:2370 | 0.0499842271994 | 0.111111111111 | CD9 | ITGA2B-ITGB3-CD9 complex |
| CORUM:2770 | 0.0499842271994 | 0.111111111111 | CD9 | ITGA6-ITGB4-CD9 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD |
|---|---|---|---|
| LGALS1 | PTGFRN | 0.997 | 0.06 |
| PTGFRN | IGDCC4 | 0.997 | |
| LGALS1 | MEGF9 | 0.993 | 0.064 |
| LGALS1 | NAGPA | 0.992 | 0.106 |
| LGALS1 | ACE | 0.982 | 0.282 |
| CD9 | IGDCC4 | 0.982 | |
| LGALS1 | ITGA1 | 0.981 | 0.18 |
| LGALS1 | CD9 | 0.98 | 0.168 |
| LGALS1 | EFCAB14 | 0.98 | 0.07 |
| CR2 | LGALS1 | 0.975 | 0.0961818181818 |
| LGALS1 | IGDCC4 | 0.974 | |
| NECTIN1 | ITGA1 | 0.955 | 0.056 |
| LGALS1 | NECTIN1 | 0.953 | 0.126 |
| ITGA1 | PTGFRN | 0.952 | 0.118 |
| ACE | MEGF9 | 0.946 | 0.078 |
| MEGF9 | EFCAB14 | 0.946 | 0.064 |
| ACE | EFCAB14 | 0.946 | 0.07 |
| ACE | ITGA1 | 0.923 | 0.14 |
| EFCAB14 | ITGA1 | 0.923 | 0.106583333333 |
| MEGF9 | NECTIN1 | 0.902 | 0.064 |
| ACE | NECTIN1 | 0.902 | 0.13 |
| CR2 | NECTIN1 | 0.902 | |
| CR2 | MEGF9 | 0.902 | |
| CR2 | ACE | 0.902 | 0.106 |
| CR2 | ITGA1 | 0.902 | 0.141583333333 |
| EFCAB14 | NECTIN1 | 0.902 | 0.054 |
| CR2 | EFCAB14 | 0.902 | |
| NECTIN1 | PTGFRN | 0.901 | 0.016 |
| CR2 | NAGPA | 0.892 | |
| MEGF9 | ITGA1 | 0.827 | 0.118 |
| NAGPA | ACE | 0.826 | 0.05 |
| ACE | PTGFRN | 0.788 | 0.08 |
| NAGPA | ITGA1 | 0.78 | 0.074 |
| NAGPA | MEGF9 | 0.757 | 0.058 |
| MEGF9 | PTGFRN | 0.722 | 0.09 |
| NAGPA | NECTIN1 | 0.715 | 0.094 |
| CR2 | PTGFRN | 0.696 | 0.044 |
| PTGFRN | CD9 | 0.643 | 0.212 |
| NAGPA | EFCAB14 | 0.541 | 0.088 |
| EFCAB14 | PTGFRN | 0.511 | 0.032 |
| NAGPA | PTGFRN | 0.341 | 0.062 |
| ACE | CD9 | 0.199 | 0.154 |
| CR2 | CD9 | 0.162 | 0.196 |
| EFCAB14 | CD9 | 0.153 | 0.066 |
| MEGF9 | CD9 | 0.153 | 0.1 |
| ITGA1 | CD9 | 0.137 | 0.064 |
| NAGPA | CD9 | 0.118 | 0.056 |
| NECTIN1 | CD9 | 0.11 | 0.08 |
| ACE | IGDCC4 | 0.027 | |
| ITGA1 | IGDCC4 | 0.027 | |
| EFCAB14 | IGDCC4 | 0.027 | |
| NAGPA | IGDCC4 | 0.027 | |
| MEGF9 | IGDCC4 | 0.027 | |
| CR2 | IGDCC4 | 0.015 | |
| NECTIN1 | IGDCC4 | 0.013 |
Related Complexes