hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_04646.1
Complex Portal: CPX-15738
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| NAB1 | NGFI-A-binding protein 1 (EGR-1-binding protein 1) (Transcriptional regulatory protein p54) | 5 | UniProt NCBI |
| EGR1 | Early growth response protein 1 (EGR-1) (AT225) (Nerve growth factor-induced protein A) (NGFI-A) (Transcription factor ETR103) (Transcription factor Zif268) (Zinc finger protein 225) (Zinc finger protein Krox-24) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-9031628 | 0.000847545829056 | 1.0 | NAB1 EGR1 | NGF-stimulated transcription |
| REAC:R-HSA-198725 | 0.0024452380673 | 1.0 | NAB1 EGR1 | Nuclear Events (kinase and transcription factor activation) |
| REAC:R-HSA-187037 | 0.00795599471791 | 1.0 | NAB1 EGR1 | Signaling by NTRK1 (TRKA) |
| REAC:R-HSA-166520 | 0.0110061344455 | 1.0 | NAB1 EGR1 | Signaling by NTRKs |
| WP:WP3299 | 0.0310970405539 | 0.5 | EGR1 | let 7 inhibition of ES cell reprogramming |
| CORUM:5375 | 0.0499419797295 | 0.5 | EGR1 | EGR-EP300 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| EGR1 | NAB1 | 0.985 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
Related Complexes
| Genename | Complexes |
|---|---|
| NAB1 | huMAP3_04646.1 huMAP3_08021.1 huMAP3_09084.1 huMAP3_11220.1 |
| EGR1 | huMAP3_01180.1 huMAP3_04646.1 huMAP3_08021.1 huMAP3_09084.1 huMAP3_11843.1 huMAP3_15260.1 |