hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_04654.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| PTPN12 | Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (PTP-PEST) (Protein-tyrosine phosphatase G1) (PTPG1) | 5 | UniProt NCBI |
| PTPN18 | Tyrosine-protein phosphatase non-receptor type 18 (EC 3.1.3.48) (Brain-derived phosphatase) | 5 | UniProt NCBI |
| PSTPIP2 | Proline-serine-threonine phosphatase-interacting protein 2 (PEST phosphatase-interacting protein 2) | 3 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-9008059 | 0.000926675585137 | 0.666666666667 | PTPN12 PTPN18 | Interleukin-37 signaling |
| REAC:R-HSA-8863795 | 0.00188000535098 | 0.666666666667 | PTPN12 PTPN18 | Downregulation of ERBB2 signaling |
| REAC:R-HSA-1227986 | 0.00614555007695 | 0.666666666667 | PTPN12 PTPN18 | Signaling by ERBB2 |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| PSTPIP2 | PTPN12 | 0.996 | 0.082 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM |
| PSTPIP2 | PTPN18 | 0.996 | 0.114 | bioplex3_WMM bioplex3_HCT116 WMM_only |
Related Complexes