hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_04690.1
Complex Portal: CPX-12466
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| TPGS2 | Tubulin polyglutamylase complex subunit 2 (PGs2) | 4 | UniProt NCBI |
| NICN1 | Nicolin-1 (NPCEDRG) (Tubulin polyglutamylase complex subunit 5) (PGs5) | 4 | UniProt NCBI |
| TBC1D19 | TBC1 domain family member 19 | 3 | UniProt NCBI |
| CSTPP1 | Centriolar satellite-associated tubulin polyglutamylase complex regulator 1 | 5 | UniProt NCBI |
| LRRC49 | Leucine-rich repeat-containing protein 49 (Centriolar satellite-associated tubulin polyglutamylase complex regulator 2) (Tubulin polyglutamylase complex subunit 4) (PGs4) | 4 | UniProt NCBI |
| TPGS1 | Tubulin polyglutamylase complex subunit 1 (PGs1) | 5 | UniProt NCBI |
| TTLL1 | Polyglutamylase complex subunit TTLL1 (EC 6.3.2.-) (Tubulin polyglutamylase TTLL1) (Tubulin polyglutamylase complex subunit 3) (PGs3) (Tubulin--tyrosine ligase-like protein 1) | 5 | UniProt NCBI |
| SANBR | SANT and BTB domain regulator of class switch recombination (SANT and BTB domain regulator of CSR) | 3 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-8955332 | 1.07096021221e-09 | 0.625 | NICN1 TPGS1 TPGS2 TTLL1 LRRC49 | Carboxyterminal post-translational modifications of tubulin |
| REAC:R-HSA-597592 | 0.0405127359976 | 0.625 | NICN1 TPGS1 TPGS2 TTLL1 LRRC49 | Post-translational protein modification |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| TPGS1 | LRRC49 | 1.0 |
mutually_exclusive (Q9H6J7)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM | |
| NICN1 | LRRC49 | 1.0 |
mutually_exclusive (Q8N5T2)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| NICN1 | TBC1D19 | 1.0 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| TPGS2 | NICN1 | 1.0 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| CSTPP1 | LRRC49 | 1.0 |
structurally_consistent (Q8N5T2)
structurally_consistent (dimer) |
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 gupta_WMM | |
| NICN1 | TTLL1 | 1.0 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| TBC1D19 | TTLL1 | 1.0 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 gupta_WMM | |
| TPGS2 | LRRC49 | 1.0 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 gupta_WMM | ||
| NICN1 | CSTPP1 | 1.0 |
structurally_consistent (Q8N5T2)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| TPGS2 | TTLL1 | 1.0 |
structurally_consistent (Q9BSH3)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 gupta_WMM boldt_WMM | |
| CSTPP1 | TTLL1 | 1.0 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 gupta_WMM | ||
| TBC1D19 | LRRC49 | 1.0 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 gupta_WMM | |
| TPGS1 | CSTPP1 | 0.999 |
structurally_consistent (Q8N5T2)
structurally_consistent (dimer) |
bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 gupta_WMM WMM_only | |
| TPGS2 | CSTPP1 | 0.999 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 gupta_WMM | ||
| TPGS1 | NICN1 | 0.998 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| LRRC49 | TTLL1 | 0.998 |
structurally_consistent (Q8N5T2)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 gupta_WMM | |
| TPGS1 | TPGS2 | 0.997 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM gupta_WMM boldt_WMM WMM_only | ||
| TPGS1 | TTLL1 | 0.997 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 gupta_WMM boldt_WMM | ||
| TBC1D19 | CSTPP1 | 0.997 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 gupta_WMM WMM_only | |
| TPGS2 | TBC1D19 | 0.995 | bioplex_WMM bioplex3_WMM gupta_WMM WMM_only | ||
| LRRC49 | SANBR | 0.994 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| NICN1 | SANBR | 0.994 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| TPGS1 | TBC1D19 | 0.993 |
mutually_exclusive (Q9BSH3)
structurally_consistent (dimer) |
bioplex3_HEK293 bioplex_WMM bioplex3_WMM gupta_WMM WMM_only | |
| TPGS1 | SANBR | 0.981 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only | ||
| CSTPP1 | SANBR | 0.975 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only | ||
| TTLL1 | SANBR | 0.892 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| TBC1D19 | SANBR | 0.889 | bioplex_WMM bioplex3_WMM WMM_only | ||
| TPGS2 | SANBR | 0.773 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes
| Genename | Complexes |
|---|---|
| TPGS2 | huMAP3_04690.1 huMAP3_12791.1 |
| NICN1 | huMAP3_04690.1 huMAP3_12791.1 |
| TBC1D19 | huMAP3_04690.1 huMAP3_12791.1 |
| CSTPP1 | huMAP3_04690.1 huMAP3_12791.1 |
| LRRC49 | huMAP3_04690.1 huMAP3_12791.1 |
| TPGS1 | huMAP3_04109.1 huMAP3_04690.1 huMAP3_06076.1 huMAP3_12791.1 |
| TTLL1 | huMAP3_04690.1 huMAP3_12791.1 |
| SANBR | huMAP3_04690.1 huMAP3_12791.1 |