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hu.MAP 3.0
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hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
List of Gene Names or Uniprot ACCs (ex. OFD1 PCM1 Q1MSJ5):
Enrichment (ex. cilium):
Protein (ex. Centrosomal protein):
Complex:
huMAP3_04702.1
Complex Portal:
CPX-17366
Confidence:
Extremely High
?
Proteins
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Genename
Protein Name
Uniprot Annotation Score
Links
EIF4E
Eukaryotic translation initiation factor 4E (eIF-4E) (eIF4E) (eIF-4F 25 kDa subunit) (mRNA cap-binding protein)
5
UniProt
NCBI
EIF4EBP1
Eukaryotic translation initiation factor 4E-binding protein 1 (4E-BP1) (eIF4E-binding protein 1) (Phosphorylated heat- and acid-stable protein regulated by insulin 1) (PHAS-I)
5
UniProt
NCBI
EIF4EBP2
Eukaryotic translation initiation factor 4E-binding protein 2 (4E-BP2) (eIF4E-binding protein 2)
5
UniProt
NCBI
Showing 1 to 3 of 3 entries
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Enrichments
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Term ID
Corrected Pval
Fraction Complex Coverage
Proteins
Term Name
WP:WP107
1.42815777161e-06
1.0
EIF4EBP1 EIF4EBP2 EIF4E
Translation factors
WP:WP516
0.000173183276299
0.666666666667
EIF4EBP1 EIF4E
Hypertrophy model
WP:WP3879
0.000237669979309
0.666666666667
EIF4EBP1 EIF4E
4 hydroxytamoxifen dexamethasone and retinoic acids regulation of p27 expression
GO:0031369
0.000281151120149
1.0
EIF4EBP1 EIF4EBP2 EIF4E
translation initiation factor binding
WP:WP4566
0.000927197171072
0.666666666667
EIF4EBP1 EIF4E
Translation inhibitors in chronically activated PDGFRA cells
WP:WP585
0.00144101964081
0.666666666667
EIF4EBP1 EIF4E
Interferon type I signaling pathways
REAC:R-HSA-166208
0.00188000535098
0.666666666667
EIF4EBP1 EIF4E
mTORC1-mediated signalling
KEGG:01521
0.00205509166508
0.666666666667
EIF4EBP1 EIF4E
EGFR tyrosine kinase inhibitor resistance
KEGG:04211
0.0024644071062
0.666666666667
EIF4EBP1 EIF4E
Longevity regulating pathway
WP:WP2034
0.00257262049766
0.666666666667
EIF4EBP1 EIF4E
Leptin signaling pathway
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Edges
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Protein 1
Protein 2
Score
?
ProteomeHD
?
Interface Overlap
?
Evidence
?
EIF4E
EIF4EBP2
0.998
0.124
structurally_consistent (dimer)
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 fraction
EIF4EBP1
EIF4E
0.998
0.1384
mutually_exclusive (A6NMX2)
structurally_consistent (dimer)
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 fraction
EIF4EBP1
EIF4EBP2
0.982
0.042
mutually_exclusive (P06730)
bioplex_WMM bioplex3_WMM fraction
Showing 1 to 3 of 3 entries
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Related Complexes
Genename
Complexes
EIF4EBP2
huMAP3_01924.1
huMAP3_04702.1
huMAP3_04825.1
huMAP3_07077.1
huMAP3_08691.1
huMAP3_09957.1
huMAP3_10733.1
huMAP3_12323.1
huMAP3_12383.1
huMAP3_13122.1
huMAP3_13436.1
EIF4EBP1
huMAP3_00082.1
huMAP3_01678.1
huMAP3_01924.1
huMAP3_04702.1
huMAP3_04825.1
huMAP3_07077.1
huMAP3_08691.1
huMAP3_09957.1
huMAP3_10733.1
huMAP3_12323.1
huMAP3_12383.1
huMAP3_13122.1
huMAP3_13436.1
EIF4E
huMAP3_00082.1
huMAP3_01678.1
huMAP3_01924.1
huMAP3_04702.1
huMAP3_04825.1
huMAP3_07077.1
huMAP3_08691.1
huMAP3_09957.1
huMAP3_10733.1
huMAP3_12323.1
huMAP3_12383.1
huMAP3_13122.1
huMAP3_13436.1