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hu.MAP 3.0
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hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
List of Gene Names or Uniprot ACCs (ex. OFD1 PCM1 Q1MSJ5):
Enrichment (ex. cilium):
Protein (ex. Centrosomal protein):
Complex:
huMAP3_04703.1
Complex Portal:
CPX-17325
Confidence:
Extremely High
?
Proteins
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Genename
Protein Name
Uniprot Annotation Score
Links
EIF4A1
Eukaryotic initiation factor 4A-I (eIF-4A-I) (eIF4A-I) (EC 3.6.4.13) (ATP-dependent RNA helicase eIF4A-1)
5
UniProt
NCBI
EIF4A2
Eukaryotic initiation factor 4A-II (eIF-4A-II) (eIF4A-II) (EC 3.6.4.13) (ATP-dependent RNA helicase eIF4A-2)
5
UniProt
NCBI
IBA57
Putative transferase CAF17, mitochondrial (EC 2.1.-.-) (Iron-sulfur cluster assembly factor homolog)
5
UniProt
NCBI
Showing 1 to 3 of 3 entries
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Enrichments
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Term ID
Corrected Pval
Fraction Complex Coverage
Proteins
Term Name
WP:WP4566
0.000927197171072
0.666666666667
EIF4A2 EIF4A1
Translation inhibitors in chronically activated PDGFRA cells
WP:WP107
0.00132925024934
0.666666666667
EIF4A2 EIF4A1
Translation factors
REAC:R-HSA-429947
0.00188000535098
0.666666666667
EIF4A2 EIF4A1
Deadenylation of mRNA
REAC:R-HSA-429914
0.0101009261622
0.666666666667
EIF4A2 EIF4A1
Deadenylation-dependent mRNA decay
REAC:R-HSA-72702
0.0116360425406
0.666666666667
EIF4A2 EIF4A1
Ribosomal scanning and start codon recognition
REAC:R-HSA-72649
0.0116360425406
0.666666666667
EIF4A2 EIF4A1
Translation initiation complex formation
REAC:R-HSA-72662
0.0120367347963
0.666666666667
EIF4A2 EIF4A1
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
REAC:R-HSA-1169408
0.0145828870271
0.666666666667
EIF4A2 EIF4A1
ISG15 antiviral mechanism
REAC:R-HSA-1169410
0.017372320015
0.666666666667
EIF4A2 EIF4A1
Antiviral mechanism by IFN-stimulated genes
REAC:R-HSA-156827
0.0406752460979
0.666666666667
EIF4A2 EIF4A1
L13a-mediated translational silencing of Ceruloplasmin expression
Showing 1 to 10 of 13 entries
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Protein 1
Protein 2
Score
?
ProteomeHD
?
Interface Overlap
?
Evidence
?
EIF4A1
EIF4A2
0.997
0.392
youn () bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 fraction treiber_WMM
EIF4A1
IBA57
0.974
0.038
structurally_consistent (dimer)
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM
EIF4A2
IBA57
0.105
0.04
bioplex_WMM bioplex3_WMM youn_WMM WMM_only
Showing 1 to 3 of 3 entries
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Related Complexes
Genename
Complexes
EIF4A1
huMAP3_00975.1
huMAP3_04703.1
huMAP3_06085.1
huMAP3_08346.1
huMAP3_08446.1
huMAP3_09863.1
huMAP3_09957.1
huMAP3_11246.1
huMAP3_13122.1
huMAP3_13175.1
huMAP3_13776.1
EIF4A2
huMAP3_00975.1
huMAP3_04703.1
huMAP3_06085.1
huMAP3_08346.1
huMAP3_08446.1
huMAP3_09863.1
huMAP3_09957.1
huMAP3_11246.1
huMAP3_13122.1
huMAP3_13175.1
huMAP3_13776.1
IBA57
huMAP3_04182.1
huMAP3_04703.1
huMAP3_06085.1
huMAP3_08346.1
huMAP3_09863.1
huMAP3_10461.1