hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_04707.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| NCF1 | Neutrophil cytosol factor 1 (NCF-1) (47 kDa autosomal chronic granulomatous disease protein) (47 kDa neutrophil oxidase factor) (NCF-47K) (Neutrophil NADPH oxidase factor 1) (Nox organizer 2) (Nox-organizing protein 2) (SH3 and PX domain-containing protein 1A) (p47-phox) | 5 | UniProt NCBI |
| MRE11 | Double-strand break repair protein MRE11 (EC 3.1.-.-) (Double-strand break repair protein MRE11A) (Meiotic recombination 11 homolog 1) (MRE11 homolog 1) (Meiotic recombination 11 homolog A) (MRE11 homolog A) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:03450 | 0.0176678729005 | 1.0 | MRE11 | Non-homologous end-joining |
| WP:WP2942 | 0.0318034510379 | 1.0 | MRE11 | DDX1 as a regulatory component of the Drosha microprocessor |
| HP:0100953 | 0.0495817777049 | 1.0 | MRE11 | Enlarged interhemispheric fissure |
| CORUM:72 | 0.0499436884912 | 1.0 | MRE11 | R/M complex (RAD50-MRE11 complex) |
| CORUM:263 | 0.0499436884912 | 1.0 | MRE11 | R/M complex (RAD50-MRE11 complex) |
| CORUM:264 | 0.0499436884912 | 1.0 | MRE11 | R/M complex (RAD50-MRE11 complex) |
| WP:WP5118 | 0.049976851631 | 1.0 | MRE11 | SMC1 SMC3 role in DNA damage Cornelia de Lange Syndrome |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| NCF1 | MRE11 | 0.99 | 0.146 | bioplex3_WMM bioplex3_HCT116 WMM_only |
Related Complexes
| Genename | Complexes |
|---|---|
| NCF1 | huMAP3_02263.1 huMAP3_02737.1 huMAP3_04707.1 huMAP3_11055.1 huMAP3_14139.1 |
| MRE11 | huMAP3_02263.1 huMAP3_04707.1 huMAP3_11272.1 huMAP3_11903.1 huMAP3_14612.1 |