hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_04715.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| MIS18A | Protein Mis18-alpha (FAPP1-associated protein 1) | 5 | UniProt NCBI |
| OIP5 | Protein Mis18-beta (Cancer/testis antigen 86) (CT86) (Opa-interacting protein 5) (OIP-5) | 5 | UniProt NCBI |
| CCDC170 | Coiled-coil domain-containing protein 170 | 5 | UniProt NCBI |
| MIS18BP1 | Mis18-binding protein 1 (Kinetochore-associated protein KNL-2 homolog) (HsKNL-2) (P243) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6434 | 7.01606139244e-10 | 0.75 | OIP5 MIS18A MIS18BP1 | MIS18 complex |
| REAC:R-HSA-606279 | 5.03512663474e-05 | 0.75 | OIP5 MIS18A MIS18BP1 | Deposition of new CENPA-containing nucleosomes at the centromere |
| REAC:R-HSA-774815 | 5.03512663474e-05 | 0.75 | OIP5 MIS18A MIS18BP1 | Nucleosome assembly |
| REAC:R-HSA-73886 | 0.000464818544718 | 0.75 | OIP5 MIS18A MIS18BP1 | Chromosome Maintenance |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| MIS18A | OIP5 | 1.0 | 0.292 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM |
| MIS18BP1 | MIS18A | 1.0 | 0.282 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 gupta_WMM |
| MIS18BP1 | OIP5 | 0.999 | 0.194 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 gupta_WMM |
| MIS18A | CCDC170 | 0.958 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| MIS18BP1 | CCDC170 | 0.172 | bioplex_WMM bioplex3_WMM WMM_only | |
| OIP5 | CCDC170 | 0.047 | bioplex_WMM bioplex3_WMM gupta_WMM WMM_only |
Related Complexes