hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_04718.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| SPHK1 | Sphingosine kinase 1 (SK 1) (SPK 1) (EC 2.7.1.91) (Acetyltransferase SPHK1) (EC 2.3.1.-) | 5 | UniProt NCBI |
| HERC4 | Probable E3 ubiquitin-protein ligase HERC4 (EC 2.3.2.26) (HECT domain and RCC1-like domain-containing protein 4) (HECT-type E3 ubiquitin transferase HERC4) | 5 | UniProt NCBI |
| DCXR | L-xylulose reductase (XR) (EC 1.1.1.10) (Carbonyl reductase II) (Dicarbonyl/L-xylulose reductase) (Kidney dicarbonyl reductase) (kiDCR) (Short chain dehydrogenase/reductase family 20C member 1) (Sperm surface protein P34H) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-5662853 | 0.0498224659464 | 0.333333333333 | DCXR | Essential pentosuria |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| HERC4 | SPHK1 | 0.992 | 0.07 | bioplex3_WMM bioplex3_HCT116 WMM_only |
| DCXR | SPHK1 | 0.992 | 0.074 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| HERC4 | DCXR | 0.059 | 0.048 | bioplex3_WMM WMM_only |
Related Complexes