hu.MAP 3.0: Complex View

Genename	Protein Name	Uniprot Annotation Score	Links
MAT2B	Methionine adenosyltransferase 2 subunit beta (Methionine adenosyltransferase II beta) (MAT II beta) (Putative dTDP-4-keto-6-deoxy-D-glucose 4-reductase)	5	UniProt NCBI
PGC	Gastricsin (EC 3.4.23.3) (Pepsinogen C)	5	UniProt NCBI
MAT1A	S-adenosylmethionine synthase isoform type-1 (AdoMet synthase 1) (EC 2.5.1.6) (Methionine adenosyltransferase 1) (MAT 1) (Methionine adenosyltransferase I/III) (MAT-I/III)	5	UniProt NCBI

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
WP:WP704	1.1325886453e-05	0.666666666667	MAT1A MAT2B	Methylation pathways
WP:WP4292	4.07657496791e-05	0.666666666667	MAT1A MAT2B	Methionine metabolism leading to sulfur amino acids and related disorders
WP:WP3580	0.000215044561898	0.666666666667	MAT1A MAT2B	Methionine de novo and salvage pathway
REAC:R-HSA-156581	0.00024538606603	0.666666666667	MAT1A MAT2B	Methylation
WP:WP241	0.000312323469599	0.666666666667	MAT1A MAT2B	One carbon metabolism
KEGG:00270	0.000788502734463	0.666666666667	MAT1A MAT2B	Cysteine and methionine metabolism
WP:WP2525	0.00167805708824	0.666666666667	MAT1A MAT2B	Trans sulfuration one carbon metabolism and related pathways
KEGG:01230	0.00168280767129	0.666666666667	MAT1A MAT2B	Biosynthesis of amino acids
GO:0048269	0.00421361424067	0.666666666667	MAT1A MAT2B	methionine adenosyltransferase complex
KEGG:01240	0.00676143238566	0.666666666667	MAT1A MAT2B	Biosynthesis of cofactors
GO:0006556	0.00842684400117	0.666666666667	MAT1A MAT2B	S-adenosylmethionine biosynthetic process
REAC:R-HSA-156580	0.0214696523361	0.666666666667	MAT1A MAT2B	Phase II - Conjugation of compounds
CORUM:7197	0.0249718442456	0.333333333333	MAT1A	Methionine adenosyltransferase alpha1 beta-v1
WP:WP5420	0.0379798583444	0.666666666667	MAT1A MAT2B	ADHD and autism ASD linked metabolic pathways and SNP
REAC:R-HSA-5579024	0.0498224659464	0.333333333333	MAT1A	Defective MAT1A causes MATD
CORUM:7191	0.0499402709677	0.333333333333	MAT2B	Methionine adenosyltransferase alpha2 beta-v1

Protein 1	Protein 2	Score	ProteomeHD	Interface Overlap	Evidence
MAT1A	MAT2B	0.998	0.682		bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 fraction
PGC	MAT2B	0.992			bioplex3_WMM bioplex3_HCT116 WMM_only

Genename	Complexes
MAT2B	huMAP3_01848.1 huMAP3_04530.1 huMAP3_04736.1 huMAP3_09016.1 huMAP3_09237.1
PGC	huMAP3_01406.1 huMAP3_04530.1 huMAP3_04736.1 huMAP3_09237.1 huMAP3_11215.1 huMAP3_12106.1 huMAP3_13999.1 huMAP3_15244.1
MAT1A	huMAP3_00245.1 huMAP3_01848.1 huMAP3_04530.1 huMAP3_04736.1 huMAP3_09016.1 huMAP3_09237.1 huMAP3_10232.1