hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_04765.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| HCN4 | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 | 5 | UniProt NCBI |
| HCN2 | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP1992 | 8.93837738341e-06 | 1.0 | HCN4 HCN2 | Genes targeted by miRNAs in adipocytes |
| REAC:R-HSA-1296061 | 1.02525705128e-05 | 1.0 | HCN4 HCN2 | HCN channels |
| KEGG:04024 | 0.00201635192055 | 1.0 | HCN4 HCN2 | cAMP signaling pathway |
| GO:0098855 | 0.0028092043205 | 1.0 | HCN4 HCN2 | HCN channel complex |
| REAC:R-HSA-1296071 | 0.00366529395832 | 1.0 | HCN4 HCN2 | Potassium Channels |
| GO:0070305 | 0.00468200720083 | 1.0 | HCN4 HCN2 | response to cGMP |
| GO:0071321 | 0.00468200720083 | 1.0 | HCN4 HCN2 | cellular response to cGMP |
| GO:0005222 | 0.00983221512175 | 1.0 | HCN4 HCN2 | intracellular cAMP-activated cation channel activity |
| GO:0005221 | 0.016855225923 | 1.0 | HCN4 HCN2 | intracellular cyclic nucleotide-activated monoatomic cation channel activity |
| GO:0043855 | 0.016855225923 | 1.0 | HCN4 HCN2 | cyclic nucleotide-activated monoatomic ion channel activity |
| HPA:0080143 | 0.0439675380582 | 0.5 | HCN4 | caudate; neuronal projections[High] |
| GO:0005248 | 0.0491610756088 | 1.0 | HCN4 HCN2 | voltage-gated sodium channel activity |
| GO:0098719 | 0.0491610756088 | 1.0 | HCN4 HCN2 | sodium ion import across plasma membrane |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| HCN4 | HCN2 | 0.985 | bioplex3_HEK293 bioplex3_WMM WMM_only |
Related Complexes