hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_04772.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| FGB | Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain] | 5 | UniProt NCBI |
| APOA1 | Apolipoprotein A-I (Apo-AI) (ApoA-I) (Apolipoprotein A1) [Cleaved into: Proapolipoprotein A-I (ProapoA-I); Truncated apolipoprotein A-I (Apolipoprotein A-I(1-242))] | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP176 | 0.000632070972113 | 1.0 | FGB APOA1 | Folate metabolism |
| WP:WP15 | 0.000969601127591 | 1.0 | FGB APOA1 | Selenium micronutrient network |
| WP:WP2806 | 0.00124541391542 | 1.0 | FGB APOA1 | Complement system |
| WP:WP5115 | 0.00618663406037 | 1.0 | FGB APOA1 | Network map of SARS CoV 2 signaling pathway |
| REAC:R-HSA-114608 | 0.00932983916662 | 1.0 | FGB APOA1 | Platelet degranulation |
| REAC:R-HSA-76005 | 0.010244026704 | 1.0 | FGB APOA1 | Response to elevated platelet cytosolic Ca2+ |
| REAC:R-HSA-5682113 | 0.0249718442457 | 0.5 | APOA1 | Defective ABCA1 causes TGD |
| WP:WP4927 | 0.0373151717536 | 0.5 | FGB | COVID 19 thrombosis and anticoagulation |
| REAC:R-HSA-76002 | 0.0400465404229 | 1.0 | FGB APOA1 | Platelet activation, signaling and aggregation |
| KEGG:04977 | 0.0474849820587 | 0.5 | APOA1 | Vitamin digestion and absorption |
| WP:WP3601 | 0.049750157242 | 0.5 | APOA1 | Lipid particles composition |
| HP:0031799 | 0.0499436884913 | 0.5 | APOA1 | Decreased circulating apolipoprotein A-I concentration |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| FGB | APOA1 | 0.991 | 0.408 | bioplex_WMM bioplex3_WMM WMM_only boldt_WMM treiber_WMM |
Related Complexes