hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_04776.1
Complex Portal: CPX-18300
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| ZDHHC20 | Palmitoyltransferase ZDHHC20 (EC 2.3.1.225) (Acyltransferase ZDHHC20) (EC 2.3.1.-) (DHHC domain-containing cysteine-rich protein 20) (DHHC20) (Zinc finger DHHC domain-containing protein 20) | 5 | UniProt NCBI |
| LAT | Linker for activation of T-cells family member 1 (36 kDa phosphotyrosine adapter protein) (pp36) (p36-38) | 5 | UniProt NCBI |
| ZDHHC3 | Palmitoyltransferase ZDHHC3 (EC 2.3.1.225) (Acyltransferase ZDHHC3) (EC 2.3.1.-) (Protein DHHC1) (Zinc finger DHHC domain-containing protein 3) (DHHC-3) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-9694548 | 0.00405087414568 | 0.666666666667 | ZDHHC3 ZDHHC20 | Maturation of spike protein |
| REAC:R-HSA-9694635 | 0.00937397262456 | 0.666666666667 | ZDHHC3 ZDHHC20 | Translation of Structural Proteins |
| REAC:R-HSA-9772573 | 0.0128584085686 | 0.666666666667 | ZDHHC3 ZDHHC20 | Late SARS-CoV-2 Infection Events |
| CORUM:2909 | 0.0249718442456 | 0.333333333333 | LAT | PLC-gamma-2-Syk-LAT-FcR-gamma complex |
| CORUM:2913 | 0.0249718442456 | 0.333333333333 | LAT | PLC-gamma-2-LAT complex |
| CORUM:2957 | 0.0499402709677 | 0.333333333333 | LAT | LAT-GRB2 complex, Fyn-mLck(KA) or Syk kinase activated |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| LAT | ZDHHC3 | 0.997 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| ZDHHC20 | LAT | 0.997 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| ZDHHC20 | ZDHHC3 | 0.384 | 0.134 | bioplex3_WMM WMM_only |
Related Complexes