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hu.MAP 3.0
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hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
List of Gene Names or Uniprot ACCs (ex. OFD1 PCM1 Q1MSJ5):
Enrichment (ex. cilium):
Protein (ex. Centrosomal protein):
Complex:
huMAP3_04785.1
Complex Portal:
CPX-13228
Confidence:
Extremely High
?
Proteins
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Genename
Protein Name
Uniprot Annotation Score
Links
DNMT3A
DNA (cytosine-5)-methyltransferase 3A (Dnmt3a) (EC 2.1.1.37) (Cysteine methyltransferase DNMT3A) (EC 2.1.1.-) (DNA methyltransferase HsaIIIA) (DNA MTase HsaIIIA) (M.HsaIIIA)
5
UniProt
NCBI
DNMT3B
DNA (cytosine-5)-methyltransferase 3B (Dnmt3b) (EC 2.1.1.37) (DNA methyltransferase HsaIIIB) (DNA MTase HsaIIIB) (M.HsaIIIB)
5
UniProt
NCBI
PCDHA1
Protocadherin alpha-1 (PCDH-alpha-1)
5
UniProt
NCBI
PCDHA4
Protocadherin alpha-4 (PCDH-alpha-4)
5
UniProt
NCBI
TCL1A
T-cell leukemia/lymphoma protein 1A (Oncogene TCL-1) (Oncogene TCL1) (Protein p14 TCL1)
5
UniProt
NCBI
Showing 1 to 5 of 5 entries
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Enrichments
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Term ID
Corrected Pval
Fraction Complex Coverage
Proteins
Term Name
WP:WP4288
0.00100346979189
0.4
DNMT3A DNMT3B
MTHFR deficiency
WP:WP3657
0.00100346979189
0.4
DNMT3A DNMT3B
Hematopoietic stem cell gene regulation by GABP alpha beta complex
REAC:R-HSA-4655427
0.001593300657
0.4
DNMT3A DNMT3B
SUMOylation of DNA methylation proteins
WP:WP241
0.00161852668418
0.4
DNMT3A DNMT3B
One carbon metabolism
KEGG:00270
0.00467646579264
0.4
DNMT3A DNMT3B
Cysteine and methionine metabolism
GO:0090116
0.00468200720083
0.4
DNMT3A DNMT3B
C-5 methylation of cytosine
WP:WP2525
0.00867145853418
0.4
DNMT3A DNMT3B
Trans sulfuration one carbon metabolism and related pathways
GO:0003886
0.0140440992017
0.4
DNMT3A DNMT3B
DNA (cytosine-5-)-methyltransferase activity
GO:0032776
0.0140440992017
0.4
DNMT3A DNMT3B
DNA methylation on cytosine
GO:0009008
0.0140440992017
0.4
DNMT3A DNMT3B
DNA-methyltransferase activity
Showing 1 to 10 of 17 entries
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Protein 1
Protein 2
Score
?
ProteomeHD
?
Interface Overlap
?
Evidence
?
TCL1A
DNMT3B
0.998
structurally_consistent (dimer)
bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only
PCDHA4
PCDHA1
0.998
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116
TCL1A
DNMT3A
0.997
0.104
structurally_consistent (dimer)
bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only
DNMT3A
DNMT3B
0.989
mutually_exclusive (P56279)
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM
PCDHA4
TCL1A
0.984
bioplex3_WMM bioplex3_HCT116 WMM_only
PCDHA4
DNMT3A
0.981
bioplex3_WMM bioplex3_HCT116 WMM_only
PCDHA4
DNMT3B
0.981
bioplex3_WMM bioplex3_HCT116 WMM_only
TCL1A
PCDHA1
0.902
bioplex3_WMM WMM_only
DNMT3A
PCDHA1
0.869
bioplex3_WMM WMM_only
DNMT3B
PCDHA1
0.768
bioplex3_WMM WMM_only
Showing 1 to 10 of 10 entries
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Related Complexes
Genename
Complexes
PCDHA4
huMAP3_02153.1
huMAP3_02268.1
huMAP3_04785.1
huMAP3_05917.1
huMAP3_06872.1
huMAP3_08823.1
huMAP3_09069.1
huMAP3_10321.1
huMAP3_14604.1
TCL1A
huMAP3_02153.1
huMAP3_04785.1
huMAP3_05917.1
huMAP3_08823.1
huMAP3_09069.1
huMAP3_14604.1
DNMT3A
huMAP3_02153.1
huMAP3_04785.1
huMAP3_05917.1
huMAP3_08823.1
huMAP3_09069.1
huMAP3_14604.1
DNMT3B
huMAP3_02153.1
huMAP3_04785.1
huMAP3_05917.1
huMAP3_08823.1
huMAP3_09069.1
huMAP3_14604.1
PCDHA1
huMAP3_04785.1
huMAP3_05917.1
huMAP3_06872.1
huMAP3_08823.1
huMAP3_09069.1
huMAP3_10321.1
huMAP3_14604.1