hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_04792.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| VPS28 | Vacuolar protein sorting-associated protein 28 homolog (H-Vps28) (ESCRT-I complex subunit VPS28) | 5 | UniProt NCBI |
| MVB12B | Multivesicular body subunit 12B (ESCRT-I complex subunit MVB12B) (Protein FAM125B) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-174490 | 0.000155497319444 | 1.0 | VPS28 MVB12B | Membrane binding and targetting of GAG proteins |
| REAC:R-HSA-174495 | 0.000155497319444 | 1.0 | VPS28 MVB12B | Synthesis And Processing Of GAG, GAGPOL Polyproteins |
| REAC:R-HSA-175474 | 0.000205051410255 | 1.0 | VPS28 MVB12B | Assembly Of The HIV Virion |
| REAC:R-HSA-162588 | 0.000599775374997 | 1.0 | VPS28 MVB12B | Budding and maturation of HIV virion |
| REAC:R-HSA-917729 | 0.000743311362176 | 1.0 | VPS28 MVB12B | Endosomal Sorting Complex Required For Transport (ESCRT) |
| REAC:R-HSA-9615710 | 0.000847545829056 | 1.0 | VPS28 MVB12B | Late endosomal microautophagy |
| KEGG:04144 | 0.00431866393369 | 1.0 | VPS28 MVB12B | Endocytosis |
| REAC:R-HSA-9610379 | 0.00828920325958 | 1.0 | VPS28 MVB12B | HCMV Late Events |
| REAC:R-HSA-162599 | 0.0143279672916 | 1.0 | VPS28 MVB12B | Late Phase of HIV Life Cycle |
| REAC:R-HSA-9612973 | 0.0168654784935 | 1.0 | VPS28 MVB12B | Autophagy |
| REAC:R-HSA-9609646 | 0.0171064139006 | 1.0 | VPS28 MVB12B | HCMV Infection |
| REAC:R-HSA-162587 | 0.0171064139006 | 1.0 | VPS28 MVB12B | HIV Life Cycle |
| GO:0000813 | 0.0210690324038 | 1.0 | VPS28 MVB12B | ESCRT I complex |
| REAC:R-HSA-162906 | 0.0415399981943 | 1.0 | VPS28 MVB12B | HIV Infection |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| MVB12B | VPS28 | 0.999 | 0.094 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
Related Complexes