hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_04816.1
Complex Portal: CPX-11289
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| SENP7 | Sentrin-specific protease 7 (EC 3.4.22.-) (SUMO-1-specific protease 2) (Sentrin/SUMO-specific protease SENP7) | 5 | UniProt NCBI |
| DAXX | Death domain-associated protein 6 (Daxx) (hDaxx) (ETS1-associated protein 1) (EAP1) (Fas death domain-associated protein) | 5 | UniProt NCBI |
| SETDB2 | Histone-lysine N-methyltransferase SETDB2 (EC 2.1.1.366) (Chronic lymphocytic leukemia deletion region gene 8 protein) (Lysine N-methyltransferase 1F) (SET domain bifurcated 2) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HPA:0030073 | 0.00731212240844 | 1.0 | SENP7 SETDB2 DAXX | appendix; lymphoid tissue[High] |
| HPA:0310443 | 0.0282627999284 | 1.0 | SENP7 SETDB2 DAXX | lymph node; non-germinal center cells[High] |
| HPA:0600443 | 0.0359795023139 | 1.0 | SENP7 SETDB2 DAXX | tonsil; non-germinal center cells[High] |
| CORUM:1490 | 0.0499402709677 | 0.333333333333 | DAXX | DAXX-DNMT1-DMAP1 complex |
| CORUM:2839 | 0.0499402709677 | 0.333333333333 | DAXX | ATRX-DAXX complex |
| CORUM:2843 | 0.0499402709677 | 0.333333333333 | DAXX | ATRX-DAXX complex |
| CORUM:3168 | 0.0499402709677 | 0.333333333333 | DAXX | DAXX-AXIN complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| SETDB2 | DAXX | 0.995 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| SETDB2 | SENP7 | 0.994 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| SENP7 | DAXX | 0.993 | 0.11 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only |
Related Complexes