hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_04822.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| IER5L | Immediate early response gene 5-like protein | 2 | UniProt NCBI |
| IER5 | Immediate early response gene 5 protein | 5 | UniProt NCBI |
| ATOSB | Atos homolog protein B | 5 | UniProt NCBI |
| PPP2R2B | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform (PP2A subunit B isoform B55-beta) (PP2A subunit B isoform PR55-beta) (PP2A subunit B isoform R2-beta) (PP2A subunit B isoform beta) | 5 | UniProt NCBI |
| PI3 | Elafin (Elastase-specific inhibitor) (ESI) (Peptidase inhibitor 3) (PI-3) (Protease inhibitor WAP3) (Skin-derived antileukoproteinase) (SKALP) (WAP four-disulfide core domain protein 14) | 5 | UniProt NCBI |
| PPP2R2C | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform (IMYPNO1) (PP2A subunit B isoform B55-gamma) (PP2A subunit B isoform PR55-gamma) (PP2A subunit B isoform R2-gamma) (PP2A subunit B isoform gamma) | 4 | UniProt NCBI |
| SERTAD2 | SERTA domain-containing protein 2 (Transcriptional regulator interacting with the PHD-bromodomain 2) (TRIP-Br2) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0000159 | 0.00156505859778 | 0.5 | PPP2R2B IER5 PPP2R2C | protein phosphatase type 2A complex |
| WP:WP500 | 0.00666790414994 | 0.333333333333 | PPP2R2B PPP2R2C | Glycogen synthesis and degradation |
| KEGG:05142 | 0.0273964025417 | 0.333333333333 | PPP2R2B PPP2R2C | Chagas disease |
| KEGG:03015 | 0.029291198851 | 0.333333333333 | PPP2R2B PPP2R2C | mRNA surveillance pathway |
| GO:0008287 | 0.037407051376 | 0.5 | PPP2R2B IER5 PPP2R2C | protein serine/threonine phosphatase complex |
| GO:1903293 | 0.037407051376 | 0.5 | PPP2R2B IER5 PPP2R2C | phosphatase complex |
| KEGG:04071 | 0.0374918580993 | 0.333333333333 | PPP2R2B PPP2R2C | Sphingolipid signaling pathway |
| KEGG:04660 | 0.0374918580993 | 0.333333333333 | PPP2R2B PPP2R2C | T cell receptor signaling pathway |
| KEGG:04728 | 0.0419636118509 | 0.333333333333 | PPP2R2B PPP2R2C | Dopaminergic synapse |
| WP:WP399 | 0.0433081873621 | 0.333333333333 | PPP2R2B PPP2R2C | Wnt signaling pathway and pluripotency |
| KEGG:04152 | 0.045081780015 | 0.333333333333 | PPP2R2B PPP2R2C | AMPK signaling pathway |
| KEGG:04261 | 0.0499639151988 | 0.333333333333 | PPP2R2B PPP2R2C | Adrenergic signaling in cardiomyocytes |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| PPP2R2B | ATOSB | 0.999 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| IER5 | PPP2R2B | 0.998 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | |
| SERTAD2 | PPP2R2B | 0.997 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| PPP2R2C | PPP2R2B | 0.996 | 0.706 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| IER5 | PPP2R2C | 0.992 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| PPP2R2C | SERTAD2 | 0.985 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| IER5L | PPP2R2B | 0.982 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| PI3 | PPP2R2B | 0.968 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| IER5 | ATOSB | 0.902 | bioplex3_WMM WMM_only | |
| IER5L | ATOSB | 0.902 | bioplex3_WMM WMM_only | |
| SERTAD2 | ATOSB | 0.902 | bioplex3_WMM WMM_only | |
| IER5 | SERTAD2 | 0.737 | bioplex3_WMM WMM_only | |
| SERTAD2 | IER5L | 0.455 | bioplex3_WMM WMM_only | |
| IER5 | IER5L | 0.455 | bioplex3_WMM WMM_only | |
| PPP2R2C | IER5L | 0.288 | bioplex3_WMM WMM_only | |
| IER5 | PI3 | 0.274 | bioplex3_WMM WMM_only | |
| SERTAD2 | PI3 | 0.274 | bioplex3_WMM WMM_only | |
| PI3 | IER5L | 0.214 | bioplex3_WMM WMM_only | |
| PI3 | ATOSB | 0.214 | bioplex3_WMM WMM_only | |
| PPP2R2C | ATOSB | 0.146 | bioplex3_WMM WMM_only | |
| PPP2R2C | PI3 | 0.078 | bioplex3_WMM WMM_only |
Related Complexes