hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_04823.1
Complex Portal: CPX-19892
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| INTS6 | Integrator complex subunit 6 (Int6) (DBI-1) (Protein DDX26) (Protein deleted in cancer 1) (DICE1) | 5 | UniProt NCBI |
| FOXC1 | Forkhead box protein C1 (Forkhead-related protein FKHL7) (Forkhead-related transcription factor 3) (FREAC-3) | 5 | UniProt NCBI |
| INTS1 | Integrator complex subunit 1 (Int1) | 5 | UniProt NCBI |
| INTS12 | Integrator complex subunit 12 (Int12) (PHD finger protein 22) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:1153 | 1.54282047245e-07 | 0.75 | INTS1 INTS6 INTS12 | Integrator complex |
| CORUM:1155 | 2.0055636204e-07 | 0.75 | INTS1 INTS6 INTS12 | Integrator-RNAPII complex |
| REAC:R-HSA-6807505 | 8.33911915483e-05 | 0.75 | INTS1 INTS6 INTS12 | RNA polymerase II transcribes snRNA genes |
| GO:0032039 | 0.000372255315939 | 0.75 | INTS1 INTS6 INTS12 | integrator complex |
| GO:0034472 | 0.000510886175237 | 0.75 | INTS1 INTS6 INTS12 | snRNA 3'-end processing |
| GO:0016180 | 0.000998468305694 | 0.75 | INTS1 INTS6 INTS12 | snRNA processing |
| GO:0016073 | 0.00847564117007 | 0.75 | INTS1 INTS6 INTS12 | snRNA metabolic process |
| GO:0034243 | 0.0291371139957 | 0.75 | INTS1 INTS6 INTS12 | regulation of transcription elongation by RNA polymerase II |
| GO:0031123 | 0.0364824972322 | 0.75 | INTS1 INTS6 INTS12 | RNA 3'-end processing |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| INTS1 | INTS12 | 1.0 | 0.49 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM Malo fraction | |
| FOXC1 | INTS1 | 0.985 | 0.088 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM WMM_only | |
| FOXC1 | INTS6 | 0.965 | 0.1 | hein_WMM bioplex_WMM bioplex3_WMM WMM_only | |
| FOXC1 | INTS12 | 0.962 | 0.148 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM WMM_only | |
| INTS6 | INTS1 | 0.955 | 0.728 |
structurally_consistent (Q9H0H0)
|
hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| INTS6 | INTS12 | 0.954 | 0.48 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
Related Complexes