hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_04830.1
Complex Portal: CPX-16355
Confidence: Extremely High  
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| ELP6 | Elongator complex protein 6 (Angiotonin-transactivated protein 1) (Protein TMEM103) | 5 | UniProt   NCBI |
| ELP5 | Elongator complex protein 5 (Dermal papilla-derived protein 6) (S-phase 2 protein) | 5 | UniProt   NCBI |
| ELP4 | Elongator complex protein 4 (hELP4) (PAX6 neighbor gene protein) | 5 | UniProt   NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
|   CORUM:6332 | 4.67737426163e-09 | 1.0 | ELP6 ELP4 ELP5 | Elongator complex (ELP1, ELP2, ELP3, ELP4, ELP5, ELP6) |
|   GO:0033588 | 1.92240082153e-06 | 1.0 | ELP6 ELP4 ELP5 | elongator holoenzyme complex |
|   GO:0002098 | 6.5361627932e-05 | 1.0 | ELP6 ELP4 ELP5 | tRNA wobble uridine modification |
|   GO:0002097 | 0.000109576846827 | 1.0 | ELP6 ELP4 ELP5 | tRNA wobble base modification |
|   REAC:R-HSA-3214847 | 0.00016307931474 | 1.0 | ELP6 ELP4 ELP5 | HATs acetylate histones |
|   REAC:R-HSA-3247509 | 0.00120056730917 | 1.0 | ELP6 ELP4 ELP5 | Chromatin modifying enzymes |
|   REAC:R-HSA-4839726 | 0.00120056730917 | 1.0 | ELP6 ELP4 ELP5 | Chromatin organization |
|   GO:0006400 | 0.00915870199393 | 1.0 | ELP6 ELP4 ELP5 | tRNA modification |
|   GO:0008033 | 0.0225051619375 | 1.0 | ELP6 ELP4 ELP5 | tRNA processing |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
|  ELP5 |  ELP6 | 1.0 | 0.386           |          | bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     youn_WMM     bioplex3_HCT116     gupta_WMM     |
|  ELP4 |  ELP6 | 1.0 | 0.57           |          | bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     youn_WMM     bioplex3_HCT116     gupta_WMM     |
|  ELP4 |  ELP5 | 0.996 | 0.438           |          | bioplex3_HEK293     bioplex_WMM     bioplex3_WMM     youn_WMM     bioplex3_HCT116     gupta_WMM     WMM_only     |
Related Complexes
| Genename | Complexes |
|---|---|
| ELP6 | huMAP3_04104.1 huMAP3_04830.1 huMAP3_09540.1 huMAP3_11045.1 |
| ELP5 | huMAP3_04104.1 huMAP3_04830.1 huMAP3_06305.1 huMAP3_11045.1 |
| ELP4 | huMAP3_04104.1 huMAP3_04830.1 huMAP3_06305.1 huMAP3_11045.1 |