hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_04843.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| TAF1A | TATA box-binding protein-associated factor RNA polymerase I subunit A (RNA polymerase I-specific TBP-associated factor 48 kDa) (TAFI48) (TATA box-binding protein-associated factor 1A) (TBP-associated factor 1A) (Transcription factor SL1) (Transcription initiation factor SL1/TIF-IB subunit A) | 5 | UniProt NCBI |
| TAF1C | TATA box-binding protein-associated factor RNA polymerase I subunit C (RNA polymerase I-specific TBP-associated factor 110 kDa) (TAFI110) (TATA box-binding protein-associated factor 1C) (TBP-associated factor 1C) (Transcription initiation factor SL1/TIF-IB subunit C) | 5 | UniProt NCBI |
| TAF1D | TATA box-binding protein-associated factor RNA polymerase I subunit D (RNA polymerase I-specific TBP-associated factor 41 kDa) (TAFI41) (TATA box-binding protein-associated factor 1D) (TBP-associated factor 1D) (Transcription initiation factor SL1/TIF-IB subunit D) | 5 | UniProt NCBI |
| TAF1B | TATA box-binding protein-associated factor RNA polymerase I subunit B (RNA polymerase I-specific TBP-associated factor 63 kDa) (TAFI63) (TATA box-binding protein-associated factor 1B) (TBP-associated factor 1B) (Transcription initiation factor SL1/TIF-IB subunit B) | 5 | UniProt NCBI |
| EPB41L4B | Band 4.1-like protein 4B (Erythrocyte membrane protein band 4.1-like 4B) (FERM-containing protein CG1) (Protein EHM2) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:5727 | 1.12081835382e-08 | 0.6 | TAF1C TAF1A TAF1B | TBP-TAF complex |
| REAC:R-HSA-73863 | 1.34205029003e-08 | 0.8 | TAF1C TAF1B TAF1A TAF1D | RNA Polymerase I Transcription Termination |
| REAC:R-HSA-73762 | 7.60097837806e-08 | 0.8 | TAF1C TAF1B TAF1A TAF1D | RNA Polymerase I Transcription Initiation |
| REAC:R-HSA-427359 | 1.5644237257e-07 | 0.8 | TAF1C TAF1B TAF1A TAF1D | SIRT1 negatively regulates rRNA expression |
| REAC:R-HSA-5250924 | 6.0683312796e-07 | 0.8 | TAF1C TAF1B TAF1A TAF1D | B-WICH complex positively regulates rRNA expression |
| REAC:R-HSA-73772 | 6.39162420915e-07 | 0.8 | TAF1C TAF1B TAF1A TAF1D | RNA Polymerase I Promoter Escape |
| REAC:R-HSA-5250913 | 1.24109632959e-06 | 0.8 | TAF1C TAF1B TAF1A TAF1D | Positive epigenetic regulation of rRNA expression |
| REAC:R-HSA-427413 | 1.29618484464e-06 | 0.8 | TAF1C TAF1B TAF1A TAF1D | NoRC negatively regulates rRNA expression |
| REAC:R-HSA-5250941 | 1.47248082262e-06 | 0.8 | TAF1C TAF1B TAF1A TAF1D | Negative epigenetic regulation of rRNA expression |
| REAC:R-HSA-73854 | 1.53505509692e-06 | 0.8 | TAF1C TAF1B TAF1A TAF1D | RNA Polymerase I Promoter Clearance |
| REAC:R-HSA-73864 | 1.59960095441e-06 | 0.8 | TAF1C TAF1B TAF1A TAF1D | RNA Polymerase I Transcription |
| REAC:R-HSA-212165 | 1.45553942328e-05 | 0.8 | TAF1C TAF1B TAF1A TAF1D | Epigenetic regulation of gene expression |
| GO:0006360 | 0.0294915925302 | 0.6 | TAF1C TAF1A TAF1B | transcription by RNA polymerase I |
| REAC:R-HSA-74160 | 0.046583533294 | 0.8 | TAF1C TAF1B TAF1A TAF1D | Gene expression (Transcription) |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| TAF1A | TAF1C | 0.998 | 0.178 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 treiber_WMM |
| TAF1D | TAF1B | 0.998 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| TAF1A | TAF1B | 0.997 | 0.178 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 treiber_WMM |
| TAF1A | TAF1D | 0.997 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 treiber_WMM | |
| TAF1C | TAF1B | 0.996 | 0.15 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 treiber_WMM |
| TAF1C | TAF1D | 0.995 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 fraction | |
| TAF1D | EPB41L4B | 0.974 | bioplex_WMM bioplex3_WMM WMM_only | |
| TAF1B | EPB41L4B | 0.951 | 0.054 | bioplex_WMM bioplex3_WMM WMM_only |
| TAF1A | EPB41L4B | 0.948 | 0.096 | hein_WMM bioplex_WMM bioplex3_WMM WMM_only treiber_WMM |
| TAF1C | EPB41L4B | 0.934 | 0.078 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes