hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_04847.1
Confidence: Extremely High  
ProteinsGenename | Protein Name | Uniprot Annotation Score | Links |
---|---|---|---|
SETDB1 | Histone-lysine N-methyltransferase SETDB1 (EC 2.1.1.366) (ERG-associated protein with SET domain) (ESET) (Histone H3-K9 methyltransferase 4) (H3-K9-HMTase 4) (Lysine N-methyltransferase 1E) (SET domain bifurcated 1) | 5 | UniProt   NCBI |
ATF7IP | Activating transcription factor 7-interacting protein 1 (ATF-interacting protein) (ATF-IP) (ATF7-interacting protein) (ATFa-associated modulator) (hAM) (MBD1-containing chromatin-associated factor 1) (P621) | 5 | UniProt   NCBI |
Enrichments
Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
---|---|---|---|---|
  CORUM:2238 | 1.70876175213e-06 | 1.0 | ATF7IP SETDB1 | MBD1-MCAF1-SETDB1 complex |
  CORUM:2749 | 1.70876175213e-06 | 1.0 | ATF7IP SETDB1 | SETDB1-containing HMTase complex |
  REAC:R-HSA-3214841 | 0.00389255927135 | 1.0 | ATF7IP SETDB1 | PKMTs methylate histone lysines |
  GO:0090309 | 0.0210690324038 | 1.0 | ATF7IP SETDB1 | positive regulation of DNA methylation-dependent heterochromatin formation |
  CORUM:2759 | 0.0249718442457 | 0.5 | ATF7IP | MBD1-MCAF complex |
  GO:0031453 | 0.0309012475255 | 1.0 | ATF7IP SETDB1 | positive regulation of heterochromatin formation |
  GO:0120263 | 0.0309012475255 | 1.0 | ATF7IP SETDB1 | positive regulation of heterochromatin organization |
  GO:1905269 | 0.0365196561665 | 1.0 | ATF7IP SETDB1 | positive regulation of chromatin organization |
  GO:0090308 | 0.0426062655276 | 1.0 | ATF7IP SETDB1 | regulation of DNA methylation-dependent heterochromatin formation |
  CORUM:2233 | 0.0499419797295 | 0.5 | SETDB1 | Replication-coupled CAF-1-MBD1-ETDB1 complex |
  CORUM:6345 | 0.0499419797295 | 0.5 | SETDB1 | ZNF304-corepressor complex |
  CORUM:6422 | 0.0499419797295 | 0.5 | SETDB1 | SETDB1-DNMT3A complex |
  CORUM:6423 | 0.0499419797295 | 0.5 | SETDB1 | SETDB1-DNMT3B complex |
Edges
Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
---|---|---|---|---|
 SETDB1 |  ATF7IP | 1.0 | 0.474           | hein_WMM     bioplex3_HEK293     bioplex ()     bioplex_WMM     Guru     bioplex3_WMM     hein ()     Malo     fraction     |
Related Complexes
Genename | Complexes |
---|---|
SETDB1 | huMAP3_04847.1 huMAP3_05859.1 huMAP3_07263.1 huMAP3_12714.1 huMAP3_15236.1 |
ATF7IP | huMAP3_04847.1 huMAP3_05859.1 huMAP3_07263.1 huMAP3_12714.1 huMAP3_15236.1 |