hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_04858.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| MAPK1 | Mitogen-activated protein kinase 1 (MAP kinase 1) (MAPK 1) (EC 2.7.11.24) (ERT1) (Extracellular signal-regulated kinase 2) (ERK-2) (MAP kinase isoform p42) (p42-MAPK) (Mitogen-activated protein kinase 2) (MAP kinase 2) (MAPK 2) | 5 | UniProt NCBI |
| PTPRR | Receptor-type tyrosine-protein phosphatase R (R-PTP-R) (EC 3.1.3.48) (Ch-1PTPase) (NC-PTPCOM1) (Protein-tyrosine phosphatase PCPTP1) | 5 | UniProt NCBI |
| MAPK3 | Mitogen-activated protein kinase 3 (MAP kinase 3) (MAPK 3) (EC 2.7.11.24) (ERT2) (Extracellular signal-regulated kinase 1) (ERK-1) (Insulin-stimulated MAP2 kinase) (MAP kinase isoform p44) (p44-MAPK) (Microtubule-associated protein 2 kinase) (p44-ERK1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04010 | 0.0047800367266 | 1.0 | MAPK3 PTPRR | MAPK signaling pathway |
| WP:WP382 | 0.00855530406698 | 1.0 | MAPK3 PTPRR | MAPK signaling pathway |
| CORUM:6801 | 0.0249718442457 | 0.5 | MAPK3 | VEGFR2-S1PR3-ERK1/2-PKC-alpha complex |
| WP:WP2868 | 0.0310970405539 | 0.5 | MAPK3 | TCA cycle nutrient use and invasiveness of ovarian cancer |
| CORUM:55 | 0.0499419797295 | 0.5 | MAPK3 | HDAC4-ERK1 complex |
| CORUM:6799 | 0.0499419797295 | 0.5 | MAPK3 | VEGFR2-S1PR1-ERK1/2-PKC-alpha complex |
| CORUM:6800 | 0.0499419797295 | 0.5 | MAPK3 | VEGFR2-S1PR2-ERK1/2-PKC-alpha complex |
| CORUM:6802 | 0.0499419797295 | 0.5 | MAPK3 | VEGFR2-S1PR5-ERK1/2-PKC-alpha complex |
| CORUM:7504 | 0.0499419797295 | 0.5 | MAPK3 | CD44-ERK1-ERK2-RHAMM complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| MAPK1 | MAPK3 | 0.999 | 0.446 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 fraction boldt_WMM |
| MAPK1 | PTPRR | 0.977 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| PTPRR | MAPK3 | 0.162 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
Related Complexes