hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_04869.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| OPTN | Optineurin (E3-14.7K-interacting protein) (FIP-2) (Huntingtin yeast partner L) (Huntingtin-interacting protein 7) (HIP-7) (Huntingtin-interacting protein L) (NEMO-related protein) (Optic neuropathy-inducing protein) (Transcription factor IIIA-interacting protein) (TFIIIA-IntP) | 5 | UniProt NCBI |
| NSF | Vesicle-fusing ATPase (EC 3.6.4.6) (N-ethylmaleimide-sensitive fusion protein) (NEM-sensitive fusion protein) (Vesicular-fusion protein NSF) | 5 | UniProt NCBI |
| STX12 | Syntaxin-12 | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HPA:0080133 | 0.0230059154439 | 1.0 | OPTN NSF STX12 | caudate; neuronal cells[High] |
| GO:0098876 | 0.0335943388364 | 1.0 | OPTN NSF STX12 | vesicle-mediated transport to the plasma membrane |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| NSF | STX12 | 0.979 | 0.37 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 gupta_WMM |
| OPTN | STX12 | 0.974 | 0.196 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 |
| NSF | OPTN | 0.07 | 0.116 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only |
Related Complexes