hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_04870.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| SLC17A5 | Sialin (H(+)/nitrate cotransporter) (H(+)/sialic acid cotransporter) (AST) (Membrane glycoprotein HP59) (Solute carrier family 17 member 5) (Vesicular excitatory amino acid transporter) (VEAT) | 5 | UniProt NCBI |
| SLC12A4 | Solute carrier family 12 member 4 (Electroneutral potassium-chloride cotransporter 1) (Erythroid K-Cl cotransporter 1) (hKCC1) | 5 | UniProt NCBI |
| LGALS9 | Galectin-9 (Gal-9) (Ecalectin) (Tumor antigen HOM-HD-21) | 5 | UniProt NCBI |
| ATP2B4 | Plasma membrane calcium-transporting ATPase 4 (PMCA4) (EC 7.2.2.10) (Matrix-remodeling-associated protein 1) (Plasma membrane calcium ATPase isoform 4) (Plasma membrane calcium pump isoform 4) | 5 | UniProt NCBI |
| ATG9A | Autophagy-related protein 9A (APG9-like 1) (mATG9) | 5 | UniProt NCBI |
| CD58 | Lymphocyte function-associated antigen 3 (Ag3) (Surface glycoprotein LFA-3) (CD antigen CD58) | 5 | UniProt NCBI |
| SLC12A6 | Solute carrier family 12 member 6 (Electroneutral potassium-chloride cotransporter 3) (K-Cl cotransporter 3) | 5 | UniProt NCBI |
| CD63 | CD63 antigen (Granulophysin) (Lysosomal-associated membrane protein 3) (LAMP-3) (Lysosome integral membrane protein 1) (Limp1) (Melanoma-associated antigen ME491) (OMA81H) (Ocular melanoma-associated antigen) (Tetraspanin-30) (Tspan-30) (CD antigen CD63) | 5 | UniProt NCBI |
| LGALS9B | Galectin-9B (Gal-9B) (Galectin-9-like protein A) | 4 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-425393 | 0.000536508861349 | 0.428571428571 | SLC12A6 SLC17A5 SLC12A4 | Transport of inorganic cations/anions and amino acids/oligopeptides |
| REAC:R-HSA-426117 | 0.000571118993049 | 0.285714285714 | SLC12A4 SLC12A6 | Cation-coupled Chloride cotransporters |
| REAC:R-HSA-425407 | 0.00845745881689 | 0.428571428571 | SLC12A6 SLC17A5 SLC12A4 | SLC-mediated transmembrane transport |
| GO:0016936 | 0.0294899169624 | 0.285714285714 | LGALS9 LGALS9B | galactoside binding |
| GO:0140157 | 0.0294899169624 | 0.285714285714 | SLC12A4 SLC12A6 | ammonium import across plasma membrane |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| LGALS9 | LGALS9B | 1.0 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| SLC12A4 | SLC12A6 | 0.999 | 0.306 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 gupta_WMM WMM_only |
| ATG9A | LGALS9 | 0.998 | 0.164 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| LGALS9 | SLC12A6 | 0.997 | 0.096 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| LGALS9 | CD63 | 0.996 | 0.294 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| SLC17A5 | LGALS9 | 0.996 | 0.092 | bioplex3_WMM bioplex3_HCT116 WMM_only |
| LGALS9 | ATP2B4 | 0.996 | 0.29 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| LGALS9 | CD58 | 0.994 | 0.104 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| SLC12A4 | LGALS9 | 0.993 | 0.174 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| ATP2B4 | SLC12A6 | 0.985 | 0.076 | bioplex_WMM bioplex3_WMM gupta_WMM WMM_only |
| ATP2B4 | CD63 | 0.984 | 0.072 | bioplex_WMM bioplex3_WMM WMM_only |
| ATP2B4 | LGALS9B | 0.983 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | |
| ATG9A | LGALS9B | 0.98 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | |
| CD58 | SLC12A6 | 0.978 | 0.062 | bioplex_WMM bioplex3_WMM WMM_only |
| SLC12A6 | LGALS9B | 0.978 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | |
| ATG9A | ATP2B4 | 0.977 | 0.120035714286 | bioplex_WMM bioplex3_WMM gupta_WMM WMM_only |
| CD58 | CD63 | 0.976 | 0.064 | bioplex_WMM bioplex3_WMM WMM_only |
| ATG9A | SLC12A6 | 0.969 | 0.19 | bioplex_WMM bioplex3_WMM gupta_WMM WMM_only |
| SLC12A4 | CD58 | 0.955 | 0.05 | bioplex_WMM bioplex3_WMM WMM_only |
| SLC17A5 | CD58 | 0.952 | 0.064 | bioplex_WMM bioplex3_WMM WMM_only |
| SLC12A6 | CD63 | 0.95 | 0.042 | bioplex_WMM bioplex3_WMM WMM_only |
| ATP2B4 | CD58 | 0.938 | 0.138 | bioplex_WMM bioplex3_WMM WMM_only |
| SLC12A4 | ATP2B4 | 0.928 | 0.124 | bioplex_WMM bioplex3_WMM gupta_WMM WMM_only |
| ATG9A | CD63 | 0.925 | 0.04 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only |
| SLC12A4 | CD63 | 0.918 | 0.066 | bioplex_WMM bioplex3_WMM WMM_only |
| SLC17A5 | CD63 | 0.915 | 0.238 | bioplex_WMM bioplex3_WMM WMM_only |
| SLC12A4 | LGALS9B | 0.907 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only | |
| SLC17A5 | SLC12A6 | 0.897 | 0.078 | bioplex_WMM bioplex3_WMM WMM_only |
| SLC17A5 | SLC12A4 | 0.896 | 0.116 | bioplex_WMM bioplex3_WMM WMM_only |
| CD63 | LGALS9B | 0.887 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only | |
| ATG9A | CD58 | 0.878 | 0.122 | bioplex_WMM bioplex3_WMM WMM_only |
| ATG9A | SLC12A4 | 0.863 | 0.164 | bioplex_WMM bioplex3_WMM gupta_WMM WMM_only |
| CD58 | LGALS9B | 0.841 | bioplex_WMM bioplex3_WMM WMM_only | |
| SLC17A5 | ATG9A | 0.829 | 0.138 | bioplex_WMM bioplex3_WMM WMM_only |
| SLC17A5 | ATP2B4 | 0.829 | 0.112 | bioplex_WMM bioplex3_WMM WMM_only |
| SLC17A5 | LGALS9B | 0.73 | bioplex3_WMM WMM_only |
Related Complexes