hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_04873.1
Confidence: Extremely High  
ProteinsGenename | Protein Name | Uniprot Annotation Score | Links |
---|---|---|---|
THY1 | Thy-1 membrane glycoprotein (CDw90) (Thy-1 antigen) (CD antigen CD90) | 5 | UniProt   NCBI |
PIGS | GPI transamidase component PIG-S (Phosphatidylinositol-glycan biosynthesis class S protein) | 5 | UniProt   NCBI |
PIGK | GPI-anchor transamidase (GPI transamidase) (EC 3.-.-.-) (GPI8 homolog) (hGPI8) (Phosphatidylinositol-glycan biosynthesis class K protein) (PIG-K) | 5 | UniProt   NCBI |
Enrichments
Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
---|---|---|---|---|
  REAC:R-HSA-163125 | 2.03811815253e-05 | 1.0 | PIGS THY1 PIGK | Post-translational modification: synthesis of GPI-anchored proteins |
  CORUM:994 | 3.41705576683e-05 | 0.666666666667 | PIGS PIGK | GAA1-GPI8-PIGT-PIG-PIGS complex |
  REAC:R-HSA-162791 | 0.000143154936711 | 0.666666666667 | PIGS PIGK | Attachment of GPI anchor to uPAR |
  KEGG:00563 | 0.0001601688991 | 0.666666666667 | PIGS PIGK | Glycosylphosphatidylinositol (GPI)-anchor biosynthesis |
  HP:0003282 | 0.000455401167586 | 0.666666666667 | PIGS PIGK | Low alkaline phosphatase |
  GO:0042765 | 0.0140440992017 | 0.666666666667 | PIGS PIGK | GPI-anchor transamidase complex |
  GO:0016255 | 0.0210651876021 | 0.666666666667 | PIGS PIGK | attachment of GPI anchor to protein |
  HP:0003155 | 0.037868427304 | 0.666666666667 | PIGS PIGK | Elevated circulating alkaline phosphatase concentration |
  GO:0034235 | 0.0393180950424 | 0.666666666667 | PIGK THY1 | GPI anchor binding |
  HP:0004379 | 0.047155317063 | 0.666666666667 | PIGS PIGK | Abnormality of alkaline phosphatase level |
Edges
Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
---|---|---|---|---|
 PIGS |  PIGK | 0.999 | 0.986           | hein_WMM     bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     youn_WMM     hein ()     gupta_WMM     boldt_WMM     |
 THY1 |  PIGK | 0.98 | 0.082           | bioplex3_HEK293     bioplex3_WMM     bioplex3_HCT116     WMM_only     |
 THY1 |  PIGS | 0.979 | 0.06           | bioplex3_HEK293     bioplex3_WMM     bioplex3_HCT116     WMM_only     |
Related Complexes