hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_04877.1
Complex Portal: CPX-22406
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| HSPA4L | Heat shock 70 kDa protein 4L (Heat shock 70-related protein APG-1) (Heat-shock protein family A member 4-like protein) (HSPA4-like protein) (Osmotic stress protein 94) | 4 | UniProt NCBI |
| HSPA8 | Heat shock cognate 71 kDa protein (EC 3.6.4.10) (Heat shock 70 kDa protein 8) (Lipopolysaccharide-associated protein 1) (LAP-1) (LPS-associated protein 1) | 5 | UniProt NCBI |
| HSPBP1 | Hsp70-binding protein 1 (HspBP1) (Heat shock protein-binding protein 1) (Hsp70-binding protein 2) (HspBP2) (Hsp70-interacting protein 1) (Hsp70-interacting protein 2) | 5 | UniProt NCBI |
| HSPA6 | Heat shock 70 kDa protein 6 (Heat shock 70 kDa protein B') | 5 | UniProt NCBI |
| POU2F1 | POU domain, class 2, transcription factor 1 (NF-A1) (Octamer-binding protein 1) (Oct-1) (Octamer-binding transcription factor 1) (OTF-1) | 5 | UniProt NCBI |
| ARMC1 | Armadillo repeat-containing protein 1 | 5 | UniProt NCBI |
| ILRUN | Protein ILRUN (Inflammation and lipid regulator with UBA-like and NBR1-like domains protein) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04141 | 0.0298999303213 | 0.5 | HSPA4L HSPBP1 | Protein processing in endoplasmic reticulum |
| HPA:0060873 | 0.0333763741956 | 0.5 | HSPBP1 ILRUN | bronchus; ciliated cells (ciliary rootlets)[High] |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| ARMC1 | HSPA8 | 0.998 | 0.2 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 boldt_WMM | |
| HSPA8 | POU2F1 | 0.997 | 0.258803921569 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 boldt_WMM | |
| HSPA4L | HSPA8 | 0.995 | 0.536 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt Malo bioplex3_HCT116 fraction boldt_WMM treiber_WMM | |
| ARMC1 | HSPBP1 | 0.988 | 0.094 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 fraction boldt_WMM |
| HSPA8 | HSPA6 | 0.984 | 0.55 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 boldt_WMM | |
| HSPBP1 | HSPA8 | 0.981 | 0.573482758621 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 fraction boldt_WMM |
| HSPA8 | ILRUN | 0.972 | 0.290571428571 |
mutually_exclusive (O95816)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| ARMC1 | ILRUN | 0.908 | 0.108 | bioplex_WMM bioplex3_WMM WMM_only | |
| ARMC1 | POU2F1 | 0.879 | 0.038 | bioplex_WMM bioplex3_WMM WMM_only | |
| HSPBP1 | HSPA6 | 0.787 | 0.064 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM bioplex3_HCT116 gupta_WMM boldt_WMM |
| POU2F1 | ILRUN | 0.704 | 0.128 | bioplex_WMM bioplex3_WMM WMM_only | |
| HSPBP1 | ILRUN | 0.589 | 0.078 | bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| HSPBP1 | POU2F1 | 0.571 | 0.12 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt_WMM | |
| HSPA4L | POU2F1 | 0.259 | 0.036 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM boldt_WMM WMM_only | |
| HSPA6 | POU2F1 | 0.227 | 0.04 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only | |
| HSPBP1 | HSPA4L | 0.159 | 0.104 |
mutually_exclusive (P17066)
structurally_consistent (dimer) |
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM fraction boldt_WMM |
| ARMC1 | HSPA6 | 0.088 | 0.062 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt boldt_WMM | |
| HSPA4L | ILRUN | 0.038 | 0.088 | bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | |
| ARMC1 | HSPA4L | 0.026 | 0.066 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt boldt_WMM | |
| HSPA6 | ILRUN | 0.026 | 0.122 | bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | |
| HSPA4L | HSPA6 | 0.025 | 0.084 |
structurally_consistent (dimer)
|
bioplex_WMM bioplex3_WMM boldt youn_WMM gupta_WMM boldt_WMM WMM_only |
Related Complexes