hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_04889.1
Complex Portal: CPX-10788
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| NDUFAF3 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3 | 5 | UniProt NCBI |
| NDUFB5 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial (Complex I-SGDH) (CI-SGDH) (NADH-ubiquinone oxidoreductase SGDH subunit) | 5 | UniProt NCBI |
| NDUFAF4 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 (Hormone-regulated proliferation-associated protein of 20 kDa) | 5 | UniProt NCBI |
| MT-ND4 | NADH-ubiquinone oxidoreductase chain 4 (EC 7.1.1.2) (NADH dehydrogenase subunit 4) | 5 | UniProt NCBI |
| NDUFC2 | NADH dehydrogenase [ubiquinone] 1 subunit C2 (Complex I-B14.5b) (CI-B14.5b) (Human lung cancer oncogene 1 protein) (HLC-1) (NADH-ubiquinone oxidoreductase subunit B14.5b) | 5 | UniProt NCBI |
| ACAD9 | Complex I assembly factor ACAD9, mitochondrial (Acyl-CoA dehydrogenase family member 9) (ACAD-9) (EC 1.3.8.-) | 5 | UniProt NCBI |
| NDUFS7 | NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial (EC 7.1.1.2) (Complex I-20kD) (CI-20kD) (NADH-ubiquinone oxidoreductase 20 kDa subunit) (PSST subunit) | 5 | UniProt NCBI |
| TMEM126B | Complex I assembly factor TMEM126B, mitochondrial (Transmembrane protein 126B) | 5 | UniProt NCBI |
| ECSIT | Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial (Protein SITPEC) | 5 | UniProt NCBI |
| NDUFAF1 | Complex I intermediate-associated protein 30, mitochondrial (NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-6799198 | 8.53935365045e-23 | 1.0 | ACAD9 NDUFC2 NDUFAF1 NDUFS7 NDUFAF3 NDUFB5 NDUFAF4 TMEM126B MT-ND4 ECSIT | Complex I biogenesis |
| REAC:R-HSA-611105 | 3.08077038596e-20 | 1.0 | ACAD9 NDUFC2 NDUFAF1 NDUFS7 NDUFAF3 NDUFB5 NDUFAF4 TMEM126B MT-ND4 ECSIT | Respiratory electron transport |
| GO:0032981 | 3.0861659774e-20 | 1.0 | ACAD9 NDUFC2 NDUFAF1 NDUFS7 NDUFAF3 NDUFB5 NDUFAF4 TMEM126B MT-ND4 ECSIT | mitochondrial respiratory chain complex I assembly |
| GO:0010257 | 3.0861659774e-20 | 1.0 | ACAD9 NDUFC2 NDUFAF1 NDUFS7 NDUFAF3 NDUFB5 NDUFAF4 TMEM126B MT-ND4 ECSIT | NADH dehydrogenase complex assembly |
| WP:WP4324 | 7.46217053803e-20 | 0.9 | ACAD9 NDUFC2 NDUFAF1 NDUFAF3 NDUFB5 NDUFAF4 TMEM126B MT-ND4 ECSIT | Mitochondrial complex I assembly model OXPHOS system |
| REAC:R-HSA-163200 | 2.50200141341e-19 | 1.0 | ACAD9 NDUFC2 NDUFAF1 NDUFS7 NDUFAF3 NDUFB5 NDUFAF4 TMEM126B MT-ND4 ECSIT | Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. |
| GO:0033108 | 2.9516014715e-18 | 1.0 | ACAD9 NDUFC2 NDUFAF1 NDUFS7 NDUFAF3 NDUFB5 NDUFAF4 TMEM126B MT-ND4 ECSIT | mitochondrial respiratory chain complex assembly |
| REAC:R-HSA-1428517 | 7.89488434471e-18 | 1.0 | ACAD9 NDUFC2 NDUFAF1 NDUFS7 NDUFAF3 NDUFB5 NDUFAF4 TMEM126B MT-ND4 ECSIT | The citric acid (TCA) cycle and respiratory electron transport |
| GO:0007005 | 7.55981634074e-12 | 1.0 | ACAD9 NDUFC2 NDUFAF1 NDUFS7 NDUFAF3 NDUFB5 NDUFAF4 TMEM126B MT-ND4 ECSIT | mitochondrion organization |
| GO:0005743 | 8.83305296508e-12 | 1.0 | ACAD9 NDUFC2 NDUFAF1 NDUFS7 NDUFAF3 NDUFB5 NDUFAF4 TMEM126B MT-ND4 ECSIT | mitochondrial inner membrane |
| HP:0003287 | 1.55591148321e-11 | 0.8 | NDUFS7 NDUFC2 ACAD9 NDUFAF3 NDUFAF4 NDUFAF1 TMEM126B MT-ND4 | Abnormality of mitochondrial metabolism |
| GO:0019866 | 1.57004426677e-11 | 1.0 | ACAD9 NDUFC2 NDUFAF1 NDUFS7 NDUFAF3 NDUFB5 NDUFAF4 TMEM126B MT-ND4 ECSIT | organelle inner membrane |
| HP:0011923 | 2.83051282997e-11 | 0.7 | NDUFS7 NDUFC2 ACAD9 NDUFAF3 NDUFAF4 NDUFAF1 TMEM126B | Decreased activity of mitochondrial complex I |
| HP:0012103 | 4.4242032386e-11 | 0.8 | NDUFS7 NDUFC2 ACAD9 NDUFAF3 NDUFAF4 NDUFAF1 TMEM126B MT-ND4 | Abnormality of the mitochondrion |
| HP:0008316 | 4.92951883737e-11 | 0.6 | NDUFS7 NDUFAF3 NDUFAF4 NDUFAF1 TMEM126B MT-ND4 | Abnormal mitochondria in muscle tissue |
| HP:0000114 | 1.61929747017e-10 | 0.6 | NDUFS7 NDUFAF3 NDUFAF4 NDUFAF1 TMEM126B MT-ND4 | Proximal tubulopathy |
| GO:0031966 | 2.63151982955e-10 | 1.0 | ACAD9 NDUFC2 NDUFAF1 NDUFS7 NDUFAF3 NDUFB5 NDUFAF4 TMEM126B MT-ND4 ECSIT | mitochondrial membrane |
| HP:0001138 | 3.45725679823e-10 | 0.6 | NDUFS7 NDUFAF3 NDUFAF4 NDUFAF1 TMEM126B MT-ND4 | Optic neuropathy |
| HP:0008972 | 3.85582673754e-10 | 0.7 | NDUFS7 NDUFC2 ACAD9 NDUFAF3 NDUFAF4 NDUFAF1 TMEM126B | Decreased activity of mitochondrial respiratory chain |
| HP:0003737 | 3.8884987301e-10 | 0.6 | NDUFS7 NDUFAF3 NDUFAF4 NDUFAF1 TMEM126B MT-ND4 | Mitochondrial myopathy |
| HP:0011922 | 4.8037979692e-10 | 0.7 | NDUFS7 NDUFC2 ACAD9 NDUFAF3 NDUFAF4 NDUFAF1 TMEM126B | Abnormal activity of mitochondrial respiratory chain |
| GO:0005740 | 5.07254373587e-10 | 1.0 | ACAD9 NDUFC2 NDUFAF1 NDUFS7 NDUFAF3 NDUFB5 NDUFAF4 TMEM126B MT-ND4 ECSIT | mitochondrial envelope |
| KEGG:04714 | 5.62344564439e-10 | 0.7 | NDUFS7 NDUFC2 NDUFAF1 NDUFAF3 NDUFB5 NDUFAF4 MT-ND4 | Thermogenesis |
| HP:0003128 | 3.87189654712e-09 | 0.7 | NDUFS7 ACAD9 NDUFAF3 NDUFAF4 NDUFAF1 TMEM126B MT-ND4 | Lactic acidosis |
| HP:0003800 | 4.4966677909e-09 | 0.6 | NDUFS7 NDUFAF3 NDUFAF4 NDUFAF1 TMEM126B MT-ND4 | Muscle abnormality related to mitochondrial dysfunction |
| HP:0001941 | 4.95966766285e-09 | 0.8 | NDUFS7 NDUFC2 ACAD9 NDUFAF3 NDUFAF4 NDUFAF1 TMEM126B MT-ND4 | Acidosis |
| HP:0004360 | 8.01745391246e-09 | 0.8 | NDUFS7 NDUFC2 ACAD9 NDUFAF3 NDUFAF4 NDUFAF1 TMEM126B MT-ND4 | Abnormality of acid-base homeostasis |
| HP:0012748 | 1.0475564758e-08 | 0.5 | TMEM126B NDUFAF3 NDUFAF4 NDUFAF1 NDUFS7 | Focal T2 hyperintense brainstem lesion |
| HP:0000817 | 1.21437447178e-08 | 0.6 | NDUFS7 NDUFC2 NDUFAF3 NDUFAF4 NDUFAF1 TMEM126B | Reduced eye contact |
| HP:0034435 | 1.21437447178e-08 | 0.6 | NDUFS7 NDUFC2 NDUFAF3 NDUFAF4 NDUFAF1 TMEM126B | Abnormal eye contact |
| HP:0000124 | 1.29593672088e-08 | 0.6 | NDUFS7 NDUFAF3 NDUFAF4 NDUFAF1 TMEM126B MT-ND4 | Renal tubular dysfunction |
| HP:0002490 | 1.47278034972e-08 | 0.6 | NDUFS7 NDUFAF3 NDUFAF4 NDUFAF1 TMEM126B MT-ND4 | Increased CSF lactate |
| HP:0030085 | 1.47278034972e-08 | 0.6 | NDUFS7 NDUFAF3 NDUFAF4 NDUFAF1 TMEM126B MT-ND4 | Abnormal CSF lactate concentration |
| HP:0007704 | 1.66254646e-08 | 0.5 | TMEM126B NDUFAF3 NDUFAF4 NDUFAF1 NDUFS7 | Paroxysmal involuntary eye movements |
| HP:0000758 | 1.77538791255e-08 | 0.6 | NDUFS7 NDUFC2 NDUFAF3 NDUFAF4 NDUFAF1 TMEM126B | Abnormal nonverbal communicative behavior |
| HP:0012747 | 2.53693100062e-08 | 0.5 | TMEM126B NDUFAF3 NDUFAF4 NDUFAF1 NDUFS7 | Abnormal brainstem MRI signal intensity |
| GO:0031967 | 4.76824706502e-08 | 1.0 | ACAD9 NDUFC2 NDUFAF1 NDUFS7 NDUFAF3 NDUFB5 NDUFAF4 TMEM126B MT-ND4 ECSIT | organelle envelope |
| GO:0031975 | 4.76824706502e-08 | 1.0 | ACAD9 NDUFC2 NDUFAF1 NDUFS7 NDUFAF3 NDUFB5 NDUFAF4 TMEM126B MT-ND4 ECSIT | envelope |
| HP:0001639 | 4.82790530173e-08 | 0.7 | NDUFS7 ACAD9 NDUFAF3 NDUFAF4 NDUFAF1 TMEM126B MT-ND4 | Hypertrophic cardiomyopathy |
| HP:0001298 | 9.13161058642e-08 | 0.7 | NDUFS7 ACAD9 NDUFAF3 NDUFAF4 NDUFAF1 TMEM126B MT-ND4 | Encephalopathy |
| HP:0025454 | 1.01326013432e-07 | 0.6 | NDUFS7 NDUFAF3 NDUFAF4 NDUFAF1 TMEM126B MT-ND4 | Abnormal CSF metabolite concentration |
| HP:0003542 | 1.14092050423e-07 | 0.5 | TMEM126B NDUFAF3 NDUFAF4 NDUFAF1 NDUFS7 | Increased serum pyruvate |
| HP:0004366 | 1.14092050423e-07 | 0.5 | TMEM126B NDUFAF3 NDUFAF4 NDUFAF1 NDUFS7 | Abnormality of glycolysis |
| HP:0011017 | 1.24810853271e-07 | 0.8 | NDUFS7 NDUFC2 ACAD9 NDUFAF3 NDUFAF4 NDUFAF1 TMEM126B MT-ND4 | Abnormal cellular physiology |
| REAC:R-HSA-1430728 | 1.6215765193e-07 | 1.0 | ACAD9 NDUFC2 NDUFAF1 NDUFS7 NDUFAF3 NDUFB5 NDUFAF4 TMEM126B MT-ND4 ECSIT | Metabolism |
| HP:0025354 | 1.79836966988e-07 | 0.8 | NDUFS7 NDUFC2 ACAD9 NDUFAF3 NDUFAF4 NDUFAF1 TMEM126B MT-ND4 | Abnormal cellular phenotype |
| HP:0025116 | 2.00806032205e-07 | 0.5 | TMEM126B NDUFAF3 NDUFAF4 NDUFAF1 NDUFS7 | Fetal distress |
| HP:0011013 | 4.22147237585e-07 | 0.5 | TMEM126B NDUFAF3 NDUFAF4 NDUFAF1 NDUFS7 | Abnormal circulating carbohydrate concentration |
| GO:0065003 | 5.97920892157e-07 | 1.0 | ACAD9 NDUFC2 NDUFAF1 NDUFS7 NDUFAF3 NDUFB5 NDUFAF4 TMEM126B MT-ND4 ECSIT | protein-containing complex assembly |
| HP:0002151 | 1.06117529817e-06 | 0.6 | ACAD9 NDUFC2 NDUFAF4 NDUFAF1 TMEM126B MT-ND4 | Increased serum lactate |
| GO:0005739 | 1.29573592309e-06 | 1.0 | ACAD9 NDUFC2 NDUFAF1 NDUFS7 NDUFAF3 NDUFB5 NDUFAF4 TMEM126B MT-ND4 ECSIT | mitochondrion |
| HP:0000543 | 1.35062649415e-06 | 0.6 | NDUFS7 NDUFC2 NDUFAF3 NDUFAF4 NDUFAF1 TMEM126B | Optic disc pallor |
| HP:0002352 | 1.6550303976e-06 | 0.6 | NDUFS7 NDUFC2 NDUFAF3 NDUFAF4 NDUFAF1 TMEM126B | Leukoencephalopathy |
| HP:0001943 | 2.24724757895e-06 | 0.6 | NDUFS7 ACAD9 NDUFAF3 NDUFAF4 NDUFAF1 TMEM126B | Hypoglycemia |
| HP:0002415 | 2.3808745831e-06 | 0.5 | TMEM126B NDUFAF3 NDUFAF4 NDUFAF1 NDUFS7 | Leukodystrophy |
| GO:0006120 | 2.74082007825e-06 | 0.5 | NDUFC2 NDUFS7 NDUFB5 NDUFAF1 MT-ND4 | mitochondrial electron transport, NADH to ubiquinone |
| GO:0005747 | 4.27289984264e-06 | 0.5 | NDUFC2 NDUFS7 NDUFB5 NDUFAF1 MT-ND4 | mitochondrial respiratory chain complex I |
| GO:0045271 | 4.27289984264e-06 | 0.5 | NDUFC2 NDUFS7 NDUFB5 NDUFAF1 MT-ND4 | respiratory chain complex I |
| GO:0030964 | 4.27289984264e-06 | 0.5 | NDUFC2 NDUFS7 NDUFB5 NDUFAF1 MT-ND4 | NADH dehydrogenase complex |
| HP:0001638 | 4.71533020252e-06 | 0.7 | NDUFS7 ACAD9 NDUFAF3 NDUFAF4 NDUFAF1 TMEM126B MT-ND4 | Cardiomyopathy |
| WP:WP623 | 4.86176473183e-06 | 0.4 | NDUFC2 NDUFS7 NDUFB5 MT-ND4 | Oxidative phosphorylation |
| HP:0001637 | 6.49837741843e-06 | 0.7 | NDUFS7 ACAD9 NDUFAF3 NDUFAF4 NDUFAF1 TMEM126B MT-ND4 | Abnormal myocardium morphology |
| HP:0011015 | 7.60777895617e-06 | 0.6 | NDUFS7 ACAD9 NDUFAF3 NDUFAF4 NDUFAF1 TMEM126B | Abnormal blood glucose concentration |
| CORUM:2914 | 9.38562934922e-06 | 0.3 | NDUFC2 NDUFB5 MT-ND4 | Respiratory chain complex I (beta subunit) mitochondrial |
| HP:0002013 | 1.2367662883e-05 | 0.6 | NDUFS7 NDUFAF3 NDUFAF4 NDUFAF1 TMEM126B MT-ND4 | Vomiting |
| HP:0011014 | 1.60520261932e-05 | 0.7 | NDUFS7 ACAD9 NDUFAF3 NDUFAF4 NDUFAF1 TMEM126B MT-ND4 | Abnormal glucose homeostasis |
| GO:0043933 | 1.72327561395e-05 | 1.0 | ACAD9 NDUFC2 NDUFAF1 NDUFS7 NDUFAF3 NDUFB5 NDUFAF4 TMEM126B MT-ND4 ECSIT | protein-containing complex organization |
| HP:0012795 | 3.48968912114e-05 | 0.7 | NDUFS7 NDUFC2 NDUFAF3 NDUFAF4 NDUFAF1 TMEM126B MT-ND4 | Abnormal optic disc morphology |
| WP:WP111 | 3.8094353819e-05 | 0.4 | NDUFC2 NDUFS7 NDUFB5 MT-ND4 | Electron transport chain OXPHOS system in mitochondria |
| GO:0019646 | 4.10794704083e-05 | 0.5 | NDUFC2 NDUFS7 NDUFB5 NDUFAF1 MT-ND4 | aerobic electron transport chain |
| KEGG:04723 | 4.25446600686e-05 | 0.4 | NDUFC2 NDUFS7 NDUFB5 MT-ND4 | Retrograde endocannabinoid signaling |
| HP:0032180 | 4.52051592574e-05 | 0.8 | NDUFS7 NDUFC2 ACAD9 NDUFAF3 NDUFAF4 NDUFAF1 TMEM126B MT-ND4 | Abnormal circulating metabolite concentration |
| WP:WP5183 | 4.5610367044e-05 | 0.3 | ACAD9 ECSIT NDUFAF1 | SARS CoV 2 mitochondrial chronic oxidative stress and endothelial dysfunction |
| KEGG:00190 | 4.70127218921e-05 | 0.4 | NDUFC2 NDUFS7 NDUFB5 MT-ND4 | Oxidative phosphorylation |
| GO:0098803 | 5.00699545562e-05 | 0.5 | NDUFC2 NDUFS7 NDUFB5 NDUFAF1 MT-ND4 | respiratory chain complex |
| HP:0000819 | 6.05332607089e-05 | 0.6 | NDUFS7 NDUFAF3 NDUFAF4 NDUFAF1 TMEM126B MT-ND4 | Diabetes mellitus |
| GO:0042773 | 6.05657969542e-05 | 0.5 | NDUFC2 NDUFS7 NDUFB5 NDUFAF1 MT-ND4 | ATP synthesis coupled electron transport |
| GO:0042775 | 6.05657969542e-05 | 0.5 | NDUFC2 NDUFS7 NDUFB5 NDUFAF1 MT-ND4 | mitochondrial ATP synthesis coupled electron transport |
| HP:0001952 | 6.84068719898e-05 | 0.6 | NDUFS7 NDUFAF3 NDUFAF4 NDUFAF1 TMEM126B MT-ND4 | Glucose intolerance |
| GO:0005746 | 7.27476492791e-05 | 0.5 | NDUFC2 NDUFS7 NDUFB5 NDUFAF1 MT-ND4 | mitochondrial respirasome |
| GO:0070469 | 7.27476492791e-05 | 0.5 | NDUFC2 NDUFS7 NDUFB5 NDUFAF1 MT-ND4 | respirasome |
| WP:WP5038 | 8.21941130224e-05 | 0.3 | ACAD9 ECSIT NDUFAF1 | Mitochondrial immune response to SARS CoV 2 |
| HP:0000587 | 8.69946655946e-05 | 0.7 | NDUFS7 NDUFC2 NDUFAF3 NDUFAF4 NDUFAF1 TMEM126B MT-ND4 | Abnormal optic nerve morphology |
| HP:0410042 | 8.86229149688e-05 | 0.7 | NDUFS7 ACAD9 NDUFAF3 NDUFAF4 NDUFAF1 TMEM126B MT-ND4 | Abnormal liver morphology |
| CORUM:2942 | 9.22394575203e-05 | 0.2 | ECSIT NDUFAF1 | Ecsit complex (ECSIT, NDUFS3, NDUFAF1) |
| GO:0022904 | 0.000102961120901 | 0.5 | NDUFC2 NDUFS7 NDUFB5 NDUFAF1 MT-ND4 | respiratory electron transport chain |
| HP:0001254 | 0.000117769258345 | 0.5 | TMEM126B NDUFAF3 NDUFAF4 NDUFAF1 NDUFS7 | Lethargy |
| HP:0002421 | 0.000136095546511 | 0.5 | TMEM126B NDUFAF3 NDUFAF4 NDUFAF1 NDUFS7 | Poor head control |
| HP:0001627 | 0.000149223999434 | 0.8 | NDUFS7 NDUFC2 ACAD9 NDUFAF3 NDUFAF4 NDUFAF1 TMEM126B MT-ND4 | Abnormal heart morphology |
| GO:0022900 | 0.00015799006283 | 0.5 | NDUFC2 NDUFS7 NDUFB5 NDUFAF1 MT-ND4 | electron transport chain |
| HP:0002017 | 0.000200215412342 | 0.6 | NDUFS7 NDUFAF3 NDUFAF4 NDUFAF1 TMEM126B MT-ND4 | Nausea and vomiting |
| CORUM:178 | 0.000204837061439 | 0.3 | NDUFS7 NDUFB5 NDUFC2 | Respiratory chain complex I (holoenzyme), mitochondrial |
| KEGG:05415 | 0.00023206023296 | 0.4 | NDUFC2 NDUFS7 NDUFB5 MT-ND4 | Diabetic cardiomyopathy |
| GO:1990204 | 0.000295234645979 | 0.5 | NDUFC2 NDUFS7 NDUFB5 NDUFAF1 MT-ND4 | oxidoreductase complex |
| HP:0002363 | 0.000299212681792 | 0.5 | TMEM126B NDUFAF3 NDUFAF4 NDUFAF1 NDUFS7 | Abnormal brainstem morphology |
| GO:0022607 | 0.000301649426448 | 1.0 | ACAD9 NDUFC2 NDUFAF1 NDUFS7 NDUFAF3 NDUFB5 NDUFAF4 TMEM126B MT-ND4 ECSIT | cellular component assembly |
| CORUM:2936 | 0.000307240465423 | 0.2 | ECSIT NDUFAF1 | Ecsit complex (ECSIT, MT-CO2, GAPDH, TRAF6, NDUFAF1) |
| HP:0001324 | 0.000315507234642 | 0.7 | NDUFS7 ACAD9 NDUFAF3 NDUFAF4 NDUFAF1 TMEM126B MT-ND4 | Muscle weakness |
| HP:0034059 | 0.000324181931 | 0.5 | TMEM126B NDUFAF3 NDUFAF4 NDUFAF1 NDUFS7 | Abnormal fetal physiology |
| HP:0012337 | 0.000336919991388 | 0.8 | NDUFS7 NDUFC2 ACAD9 NDUFAF3 NDUFAF4 NDUFAF1 TMEM126B MT-ND4 | Abnormal homeostasis |
| KEGG:05208 | 0.000350976864595 | 0.4 | NDUFC2 NDUFS7 NDUFB5 MT-ND4 | Chemical carcinogenesis - reactive oxygen species |
| GO:0006119 | 0.000384383333576 | 0.5 | NDUFC2 NDUFS7 NDUFB5 NDUFAF1 MT-ND4 | oxidative phosphorylation |
| HP:0002921 | 0.000384575353827 | 0.6 | NDUFS7 NDUFAF3 NDUFAF4 NDUFAF1 TMEM126B MT-ND4 | Abnormal cerebrospinal fluid morphology |
| HP:0011277 | 0.000389641262339 | 0.7 | NDUFS7 ACAD9 NDUFAF3 NDUFAF4 NDUFAF1 TMEM126B MT-ND4 | Abnormality of the urinary system physiology |
| HP:0001392 | 0.000398395878372 | 0.7 | NDUFS7 ACAD9 NDUFAF3 NDUFAF4 NDUFAF1 TMEM126B MT-ND4 | Abnormality of the liver |
| HP:0001508 | 0.000398395878372 | 0.7 | NDUFS7 ACAD9 NDUFAF3 NDUFAF4 NDUFAF1 TMEM126B MT-ND4 | Failure to thrive |
| HP:0000618 | 0.000432943305146 | 0.5 | TMEM126B NDUFAF3 NDUFAF4 NDUFAF1 NDUFS7 | Blindness |
| CORUM:2939 | 0.000460692494101 | 0.2 | ECSIT NDUFAF1 | Ecsit complex (ECSIT, MT-CO2, NDUFA1, MT-ND1, TRAF6, NDUFAF1) |
| HP:0012447 | 0.000463950632926 | 0.6 | NDUFS7 NDUFAF3 NDUFAF4 NDUFAF1 TMEM126B MT-ND4 | Abnormal myelination |
| HP:0000745 | 0.000484467803517 | 0.6 | NDUFS7 NDUFAF3 NDUFAF4 NDUFAF1 TMEM126B MT-ND4 | Diminished motivation |
| HP:0002240 | 0.000489712442113 | 0.6 | NDUFS7 NDUFAF3 NDUFAF4 NDUFAF1 TMEM126B MT-ND4 | Hepatomegaly |
| GO:0008137 | 0.000499046750281 | 0.4 | NDUFC2 NDUFS7 NDUFB5 MT-ND4 | NADH dehydrogenase (ubiquinone) activity |
| HP:5200275 | 0.000522174353558 | 0.6 | NDUFS7 NDUFAF3 NDUFAF4 NDUFAF1 TMEM126B MT-ND4 | Abnormal motivation |
| GO:0050136 | 0.000552815796055 | 0.4 | NDUFC2 NDUFS7 NDUFB5 MT-ND4 | NADH dehydrogenase (quinone) activity |
| GO:0003954 | 0.000610805882605 | 0.4 | NDUFC2 NDUFS7 NDUFB5 MT-ND4 | NADH dehydrogenase activity |
| CORUM:2884 | 0.00064473409071 | 0.2 | NDUFS7 NDUFAF1 | Respiratory chain complex I (early intermediate NDUFAF1 assembly), mitochondrial |
| KEGG:05012 | 0.000671379157703 | 0.4 | NDUFC2 NDUFS7 NDUFB5 MT-ND4 | Parkinson disease |
| HP:0001252 | 0.00067259223265 | 0.8 | NDUFS7 NDUFC2 ACAD9 NDUFAF3 NDUFAF4 NDUFAF1 TMEM126B MT-ND4 | Hypotonia |
| GO:0003955 | 0.000740310437941 | 0.4 | NDUFC2 NDUFS7 NDUFB5 MT-ND4 | NAD(P)H dehydrogenase (quinone) activity |
| KEGG:05020 | 0.000752715820984 | 0.4 | NDUFC2 NDUFS7 NDUFB5 MT-ND4 | Prion disease |
| GO:0044085 | 0.000756465730475 | 1.0 | ACAD9 NDUFC2 NDUFAF1 NDUFS7 NDUFAF3 NDUFB5 NDUFAF4 TMEM126B MT-ND4 ECSIT | cellular component biogenesis |
| HP:0012211 | 0.000764064954021 | 0.6 | NDUFS7 NDUFAF3 NDUFAF4 NDUFAF1 TMEM126B MT-ND4 | Abnormal renal physiology |
| HP:0011805 | 0.000767473169639 | 0.8 | NDUFS7 NDUFC2 ACAD9 NDUFAF3 NDUFAF4 NDUFAF1 TMEM126B MT-ND4 | Abnormal skeletal muscle morphology |
| HP:0030680 | 0.000877925985098 | 0.8 | NDUFS7 NDUFC2 ACAD9 NDUFAF3 NDUFAF4 NDUFAF1 TMEM126B MT-ND4 | Abnormal cardiovascular system morphology |
| GO:0031090 | 0.000959229479862 | 1.0 | ACAD9 NDUFC2 NDUFAF1 NDUFS7 NDUFAF3 NDUFB5 NDUFAF4 TMEM126B MT-ND4 ECSIT | organelle membrane |
| HP:0003271 | 0.00105152806001 | 0.6 | NDUFS7 NDUFAF3 NDUFAF4 NDUFAF1 TMEM126B MT-ND4 | Visceromegaly |
| KEGG:05016 | 0.00111975372403 | 0.4 | NDUFC2 NDUFS7 NDUFB5 MT-ND4 | Huntington disease |
| GO:0098800 | 0.00116347530131 | 0.5 | NDUFC2 NDUFS7 NDUFB5 NDUFAF1 MT-ND4 | inner mitochondrial membrane protein complex |
| GO:0009060 | 0.00124525151289 | 0.5 | NDUFC2 NDUFS7 NDUFB5 NDUFAF1 MT-ND4 | aerobic respiration |
| HP:0002012 | 0.00146834352852 | 0.7 | NDUFS7 ACAD9 NDUFAF3 NDUFAF4 NDUFAF1 TMEM126B MT-ND4 | Abnormality of the abdominal organs |
| HP:0001438 | 0.00174065842967 | 0.6 | NDUFS7 NDUFAF3 NDUFAF4 NDUFAF1 TMEM126B MT-ND4 | Abnormal abdomen morphology |
| HP:0002060 | 0.00177461555551 | 0.8 | NDUFS7 NDUFC2 ACAD9 NDUFAF3 NDUFAF4 NDUFAF1 TMEM126B MT-ND4 | Abnormal cerebral morphology |
| HP:0001098 | 0.00186360691105 | 0.7 | NDUFS7 NDUFC2 NDUFAF3 NDUFAF4 NDUFAF1 TMEM126B MT-ND4 | Abnormal fundus morphology |
| HP:0004329 | 0.00191881999445 | 0.7 | NDUFS7 NDUFC2 NDUFAF3 NDUFAF4 NDUFAF1 TMEM126B MT-ND4 | Abnormal posterior eye segment morphology |
| GO:0016655 | 0.00199509778647 | 0.4 | NDUFC2 NDUFS7 NDUFB5 MT-ND4 | oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor |
| HP:0100547 | 0.00200164467529 | 0.8 | NDUFS7 NDUFC2 ACAD9 NDUFAF3 NDUFAF4 NDUFAF1 TMEM126B MT-ND4 | Abnormal forebrain morphology |
| HP:0011400 | 0.00202289899831 | 0.5 | TMEM126B NDUFAF3 NDUFAF4 NDUFAF1 NDUFS7 | Abnormal CNS myelination |
| KEGG:05014 | 0.00225606314239 | 0.4 | NDUFC2 NDUFS7 NDUFB5 MT-ND4 | Amyotrophic lateral sclerosis |
| GO:0015453 | 0.00230309239393 | 0.4 | NDUFC2 NDUFS7 NDUFB5 MT-ND4 | oxidoreduction-driven active transmembrane transporter activity |
| GO:0045333 | 0.00234303379171 | 0.5 | NDUFC2 NDUFS7 NDUFB5 NDUFAF1 MT-ND4 | cellular respiration |
| HP:0003808 | 0.00252172838131 | 0.8 | NDUFS7 NDUFC2 ACAD9 NDUFAF3 NDUFAF4 NDUFAF1 TMEM126B MT-ND4 | Abnormal muscle tone |
| KEGG:05010 | 0.00272365598584 | 0.4 | NDUFC2 NDUFS7 NDUFB5 MT-ND4 | Alzheimer disease |
| GO:0006996 | 0.00275494517729 | 1.0 | ACAD9 NDUFC2 NDUFAF1 NDUFS7 NDUFAF3 NDUFB5 NDUFAF4 TMEM126B MT-ND4 ECSIT | organelle organization |
| GO:0042776 | 0.0032281662843 | 0.4 | NDUFC2 NDUFS7 NDUFB5 MT-ND4 | proton motive force-driven mitochondrial ATP synthesis |
| HP:0000407 | 0.00365382916752 | 0.6 | NDUFS7 NDUFAF3 NDUFAF4 NDUFAF1 TMEM126B MT-ND4 | Sensorineural hearing impairment |
| HP:0004325 | 0.00463306341878 | 0.7 | NDUFS7 ACAD9 NDUFAF3 NDUFAF4 NDUFAF1 TMEM126B MT-ND4 | Decreased body weight |
| KEGG:04932 | 0.00484440033129 | 0.3 | NDUFS7 NDUFB5 NDUFC2 | Non-alcoholic fatty liver disease |
| GO:0015986 | 0.00495760415907 | 0.4 | NDUFC2 NDUFS7 NDUFB5 MT-ND4 | proton motive force-driven ATP synthesis |
| KEGG:05022 | 0.00585983148306 | 0.4 | NDUFC2 NDUFS7 NDUFB5 MT-ND4 | Pathways of neurodegeneration - multiple diseases |
| GO:0016651 | 0.00621318039543 | 0.4 | NDUFC2 NDUFS7 NDUFB5 MT-ND4 | oxidoreductase activity, acting on NAD(P)H |
| HP:0007364 | 0.00627387292804 | 0.7 | NDUFS7 NDUFC2 NDUFAF3 NDUFAF4 NDUFAF1 TMEM126B MT-ND4 | Aplasia/Hypoplasia of the cerebrum |
| HP:0011389 | 0.0068935984828 | 0.6 | NDUFS7 NDUFAF3 NDUFAF4 NDUFAF1 TMEM126B MT-ND4 | Functional abnormality of the inner ear |
| HP:0001939 | 0.00723948502042 | 0.8 | NDUFS7 NDUFC2 ACAD9 NDUFAF3 NDUFAF4 NDUFAF1 TMEM126B MT-ND4 | Abnormality of metabolism/homeostasis |
| HP:0034057 | 0.00782326832447 | 0.5 | TMEM126B NDUFAF3 NDUFAF4 NDUFAF1 NDUFS7 | Fetal anomaly |
| HP:0011804 | 0.00785853779194 | 0.8 | NDUFS7 NDUFC2 ACAD9 NDUFAF3 NDUFAF4 NDUFAF1 TMEM126B MT-ND4 | Abnormal muscle physiology |
| HP:0003348 | 0.00797162805718 | 0.3 | TMEM126B MT-ND4 NDUFC2 | Hyperalaninemia |
| HP:0010916 | 0.00837394992314 | 0.3 | TMEM126B MT-ND4 NDUFC2 | Abnormal circulating alanine concentration |
| HP:0010915 | 0.00837394992314 | 0.3 | TMEM126B MT-ND4 NDUFC2 | Abnormal circulating pyruvate family amino acid concentration |
| HP:0001251 | 0.00868610857683 | 0.6 | NDUFS7 NDUFAF3 NDUFAF4 NDUFAF1 TMEM126B MT-ND4 | Ataxia |
| HP:0007663 | 0.00892010100671 | 0.5 | TMEM126B NDUFAF3 NDUFAF4 NDUFAF1 NDUFS7 | Reduced visual acuity |
| WP:WP4396 | 0.00907021898379 | 0.3 | NDUFS7 NDUFB5 NDUFC2 | Nonalcoholic fatty liver disease |
| HP:0000639 | 0.00920400036008 | 0.6 | NDUFS7 NDUFAF3 NDUFAF4 NDUFAF1 TMEM126B MT-ND4 | Nystagmus |
| GO:0015980 | 0.00936346998885 | 0.5 | NDUFC2 NDUFS7 NDUFB5 NDUFAF1 MT-ND4 | energy derivation by oxidation of organic compounds |
| GO:0006754 | 0.00941974755121 | 0.4 | NDUFC2 NDUFS7 NDUFB5 MT-ND4 | ATP biosynthetic process |
| HP:0012443 | 0.00969331004682 | 0.8 | NDUFS7 NDUFC2 ACAD9 NDUFAF3 NDUFAF4 NDUFAF1 TMEM126B MT-ND4 | Abnormal brain morphology |
| HP:0012547 | 0.0100597404297 | 0.6 | NDUFS7 NDUFAF3 NDUFAF4 NDUFAF1 TMEM126B MT-ND4 | Abnormal involuntary eye movements |
| GO:0009206 | 0.0103846818546 | 0.4 | NDUFC2 NDUFS7 NDUFB5 MT-ND4 | purine ribonucleoside triphosphate biosynthetic process |
| GO:0009145 | 0.0103846818546 | 0.4 | NDUFC2 NDUFS7 NDUFB5 MT-ND4 | purine nucleoside triphosphate biosynthetic process |
| HP:0034434 | 0.0104328898526 | 0.7 | NDUFS7 NDUFC2 NDUFAF3 NDUFAF4 NDUFAF1 TMEM126B MT-ND4 | Abnormal communication |
| HP:0001626 | 0.0110749172337 | 0.8 | NDUFS7 NDUFC2 ACAD9 NDUFAF3 NDUFAF4 NDUFAF1 TMEM126B MT-ND4 | Abnormality of the cardiovascular system |
| HP:0000505 | 0.0124123316014 | 0.6 | NDUFS7 NDUFAF3 NDUFAF4 NDUFAF1 TMEM126B MT-ND4 | Visual impairment |
| HP:0033108 | 0.0126140846079 | 0.3 | TMEM126B MT-ND4 NDUFC2 | Abnormal circulating proteinogenic amino acid derivative concentration |
| GO:0009201 | 0.0131193192467 | 0.4 | NDUFC2 NDUFS7 NDUFB5 MT-ND4 | ribonucleoside triphosphate biosynthetic process |
| HP:0001511 | 0.0135593045996 | 0.5 | TMEM126B NDUFAF3 NDUFAF4 NDUFAF1 NDUFS7 | Intrauterine growth retardation |
| HP:0002093 | 0.0144454921759 | 0.5 | TMEM126B NDUFAF3 NDUFAF4 NDUFAF1 NDUFS7 | Respiratory insufficiency |
| GO:1902495 | 0.014653050387 | 0.5 | NDUFC2 NDUFS7 NDUFB5 NDUFAF1 MT-ND4 | transmembrane transporter complex |
| HP:0004323 | 0.0147921335827 | 0.7 | NDUFS7 ACAD9 NDUFAF3 NDUFAF4 NDUFAF1 TMEM126B MT-ND4 | Abnormality of body weight |
| GO:0009142 | 0.0149986773182 | 0.4 | NDUFC2 NDUFS7 NDUFB5 MT-ND4 | nucleoside triphosphate biosynthetic process |
| HPA:0360053 | 0.0153776251203 | 0.6 | ACAD9 ECSIT NDUFAF3 NDUFB5 NDUFAF1 MT-ND4 | parathyroid gland; glandular cells[High] |
| HP:0002011 | 0.0170896630622 | 0.8 | NDUFS7 NDUFC2 ACAD9 NDUFAF3 NDUFAF4 NDUFAF1 TMEM126B MT-ND4 | Morphological central nervous system abnormality |
| HP:0011443 | 0.0172581304637 | 0.6 | NDUFS7 NDUFAF3 NDUFAF4 NDUFAF1 TMEM126B MT-ND4 | Abnormality of coordination |
| GO:0009055 | 0.0185681816185 | 0.4 | NDUFC2 NDUFS7 NDUFB5 MT-ND4 | electron transfer activity |
| HP:0002977 | 0.0193025667106 | 0.7 | NDUFS7 NDUFC2 NDUFAF3 NDUFAF4 NDUFAF1 TMEM126B MT-ND4 | Aplasia/Hypoplasia involving the central nervous system |
| HP:0003011 | 0.0198241947124 | 0.8 | NDUFS7 NDUFC2 ACAD9 NDUFAF3 NDUFAF4 NDUFAF1 TMEM126B MT-ND4 | Abnormality of the musculature |
| HP:0012639 | 0.0215595631097 | 0.8 | NDUFS7 NDUFC2 ACAD9 NDUFAF3 NDUFAF4 NDUFAF1 TMEM126B MT-ND4 | Abnormal nervous system morphology |
| GO:1990351 | 0.0216697645027 | 0.5 | NDUFC2 NDUFS7 NDUFB5 NDUFAF1 MT-ND4 | transporter complex |
| HP:0004354 | 0.0227666835885 | 0.4 | TMEM126B ACAD9 MT-ND4 NDUFC2 | Abnormal circulating carboxylic acid concentration |
| HP:0001263 | 0.023124545313 | 0.7 | NDUFS7 NDUFC2 NDUFAF3 NDUFAF4 NDUFAF1 TMEM126B MT-ND4 | Global developmental delay |
| HP:0011442 | 0.0241499059442 | 0.7 | NDUFS7 NDUFC2 NDUFAF3 NDUFAF4 NDUFAF1 TMEM126B MT-ND4 | Abnormal central motor function |
| HP:0003198 | 0.0244435495936 | 0.4 | ACAD9 NDUFAF4 NDUFAF1 MT-ND4 | Myopathy |
| HP:0000079 | 0.0248221185147 | 0.7 | NDUFS7 ACAD9 NDUFAF3 NDUFAF4 NDUFAF1 TMEM126B MT-ND4 | Abnormality of the urinary system |
| WP:000000 | 0.029871335992 | 1.0 | ACAD9 NDUFC2 NDUFAF1 NDUFS7 NDUFAF3 NDUFB5 NDUFAF4 TMEM126B MT-ND4 ECSIT | WIKIPATHWAYS |
| WP:000000 | 0.029871335992 | 1.0 | ACAD9 NDUFC2 NDUFAF1 NDUFS7 NDUFAF3 NDUFB5 NDUFAF4 TMEM126B MT-ND4 ECSIT | WIKIPATHWAYS |
| GO:0098798 | 0.0316699453157 | 0.5 | NDUFC2 NDUFS7 NDUFB5 NDUFAF1 MT-ND4 | mitochondrial protein-containing complex |
| HP:0000504 | 0.0324256627704 | 0.6 | NDUFS7 NDUFAF3 NDUFAF4 NDUFAF1 TMEM126B MT-ND4 | Abnormality of vision |
| HP:0002086 | 0.0338184970792 | 0.7 | NDUFS7 NDUFC2 NDUFAF3 NDUFAF4 NDUFAF1 TMEM126B MT-ND4 | Abnormality of the respiratory system |
| HP:0000508 | 0.0367279683932 | 0.5 | TMEM126B NDUFAF3 NDUFAF4 NDUFAF1 NDUFS7 | Ptosis |
| HP:0000818 | 0.0373242767202 | 0.6 | NDUFS7 NDUFAF3 NDUFAF4 NDUFAF1 TMEM126B MT-ND4 | Abnormality of the endocrine system |
| HP:0000252 | 0.0411798868894 | 0.6 | NDUFS7 NDUFC2 NDUFAF3 NDUFAF4 NDUFAF1 TMEM126B | Microcephaly |
| HP:0040195 | 0.043435038871 | 0.6 | NDUFS7 NDUFC2 NDUFAF3 NDUFAF4 NDUFAF1 TMEM126B | Decreased head circumference |
| HP:0012072 | 0.0457022927985 | 0.3 | ACAD9 MT-ND4 TMEM126B | Aciduria |
| HP:0000077 | 0.0482475979552 | 0.6 | NDUFS7 NDUFAF3 NDUFAF4 NDUFAF1 TMEM126B MT-ND4 | Abnormality of the kidney |
| HP:0032943 | 0.0482539605636 | 0.3 | ACAD9 MT-ND4 TMEM126B | Abnormal urine pH |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| ECSIT | NDUFAF4 | 1.0 | 0.232 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 | |
| ECSIT | ACAD9 | 1.0 | 0.224 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM bioplex3_HCT116 boldt_WMM | |
| NDUFAF3 | NDUFAF4 | 0.999 | 0.692 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM boldt youn_WMM bioplex3_HCT116 boldt_WMM WMM_only | |
| NDUFC2 | NDUFS7 | 0.999 | 0.636 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| ACAD9 | NDUFAF1 | 0.999 | 0.398 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 | |
| ECSIT | NDUFAF1 | 0.999 | 0.568 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 |
| NDUFB5 | MT-ND4 | 0.999 | 0.828 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| NDUFAF4 | NDUFS7 | 0.999 | 0.242 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 boldt_WMM | |
| NDUFS7 | NDUFAF1 | 0.999 | 0.194 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 |
| ECSIT | TMEM126B | 0.999 | 0.122 |
structurally_consistent (Q16795)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| NDUFB5 | NDUFS7 | 0.999 | 0.666 |
structurally_consistent (P03905)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| ECSIT | NDUFB5 | 0.998 | 0.062 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| ACAD9 | NDUFAF4 | 0.998 | 0.182 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 | |
| NDUFB5 | NDUFAF4 | 0.998 | 0.356 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| NDUFAF4 | NDUFAF1 | 0.998 | 0.268 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 WMM_only | |
| ECSIT | NDUFAF3 | 0.998 | 0.198 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 | |
| NDUFB5 | NDUFAF1 | 0.998 | 0.33 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| ACAD9 | NDUFS7 | 0.997 | 0.418 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 | |
| NDUFAF3 | NDUFS7 | 0.997 | 0.054 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM bioplex3_HCT116 boldt_WMM | |
| NDUFC2 | NDUFB5 | 0.997 | 0.886 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| ECSIT | NDUFC2 | 0.997 | 0.108 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| NDUFC2 | NDUFAF1 | 0.997 | 0.244 |
structurally_consistent (P03891)
|
bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only |
| NDUFAF4 | TMEM126B | 0.997 | 0.258 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| ACAD9 | NDUFC2 | 0.995 | 0.202 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| ECSIT | NDUFS7 | 0.995 | 0.088 |
mutually_exclusive (P31930)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 |
| NDUFAF3 | NDUFB5 | 0.995 | 0.15 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| NDUFS7 | TMEM126B | 0.995 | 0.114 |
structurally_consistent (Q16795)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| ECSIT | MT-ND4 | 0.994 | 0.052 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| NDUFC2 | TMEM126B | 0.994 | 0.088 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| TMEM126B | NDUFAF1 | 0.993 | 0.234 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| NDUFAF3 | NDUFAF1 | 0.993 | 0.212 | bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 WMM_only | |
| ACAD9 | NDUFB5 | 0.993 | 0.29 |
structurally_consistent (O96000)
structurally_consistent (dimer) |
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| NDUFB5 | TMEM126B | 0.992 | 0.174 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| NDUFC2 | MT-ND4 | 0.992 | 0.828 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only |
| MT-ND4 | NDUFS7 | 0.991 | 0.638 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| NDUFAF3 | TMEM126B | 0.99 | 0.112 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| ACAD9 | NDUFAF3 | 0.986 | 0.198 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM |
| NDUFAF4 | MT-ND4 | 0.986 | 0.044 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only | |
| ACAD9 | TMEM126B | 0.982 | 0.178 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| NDUFC2 | NDUFAF3 | 0.982 | 0.178 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | |
| NDUFC2 | NDUFAF4 | 0.98 | 0.134 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | |
| MT-ND4 | TMEM126B | 0.972 | 0.072 | bioplex_WMM bioplex3_WMM WMM_only | |
| MT-ND4 | NDUFAF1 | 0.961 | 0.076 |
structurally_consistent (O75251)
|
bioplex_WMM bioplex3_WMM WMM_only |
| NDUFAF3 | MT-ND4 | 0.919 | 0.108 | bioplex_WMM bioplex3_WMM WMM_only | |
| ACAD9 | MT-ND4 | 0.898 | 0.174 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes