hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_04915.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| TOP2B | DNA topoisomerase 2-beta (EC 5.6.2.2) (DNA topoisomerase II, beta isozyme) | 5 | UniProt NCBI |
| PIAS4 | E3 SUMO-protein ligase PIAS4 (EC 2.3.2.27) (PIASy) (Protein inhibitor of activated STAT protein 4) (Protein inhibitor of activated STAT protein gamma) (PIAS-gamma) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-4615885 | 0.00147124386858 | 1.0 | TOP2B PIAS4 | SUMOylation of DNA replication proteins |
| REAC:R-HSA-3108232 | 0.0211937720117 | 1.0 | TOP2B PIAS4 | SUMO E3 ligases SUMOylate target proteins |
| REAC:R-HSA-2990846 | 0.0225607814134 | 1.0 | TOP2B PIAS4 | SUMOylation |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| PIAS4 | TOP2B | 0.982 | bioplex3_WMM bioplex3_HCT116 WMM_only |
Related Complexes