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hu.MAP 3.0
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hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
List of Gene Names or Uniprot ACCs (ex. OFD1 PCM1 Q1MSJ5):
Enrichment (ex. cilium):
Protein (ex. Centrosomal protein):
Complex:
huMAP3_04935.1
Complex Portal:
CPX-15356
Confidence:
Extremely High
?
Proteins
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Genename
Protein Name
Uniprot Annotation Score
Links
HSD11B1
11-beta-hydroxysteroid dehydrogenase 1 (11-DH) (11-beta-HSD1) (EC 1.1.1.146) (7-oxosteroid reductase) (EC 1.1.1.201) (Corticosteroid 11-beta-dehydrogenase isozyme 1) (Short chain dehydrogenase/reductase family 26C member 1)
5
UniProt
NCBI
HSD17B2
17-beta-hydroxysteroid dehydrogenase type 2 (17-beta-HSD 2) (20 alpha-hydroxysteroid dehydrogenase) (20-alpha-HSD) (E2DH) (Estradiol 17-beta-dehydrogenase 2) (EC 1.1.1.62) (Microsomal 17-beta-hydroxysteroid dehydrogenase) (Short chain dehydrogenase/reductase family 9C member 2) (Testosterone 17-beta-dehydrogenase) (EC 1.1.1.239)
5
UniProt
NCBI
INSR
Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: Insulin receptor subunit alpha; Insulin receptor subunit beta]
5
UniProt
NCBI
Showing 1 to 3 of 3 entries
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Enrichments
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Term ID
Corrected Pval
Fraction Complex Coverage
Proteins
Term Name
KEGG:04913
0.000102418907518
1.0
INSR HSD17B2
Ovarian steroidogenesis
WP:WP496
0.0435328773163
0.5
HSD17B2
Steroid biosynthesis
WP:WP3634
0.049750157242
0.5
INSR
Insulin signaling in adipocytes normal condition
WP:WP3635
0.049750157242
0.5
INSR
Insulin signaling in adipocytes diabetic condition
WP:WP5320
0.049750157242
0.5
HSD17B2
Male steroid hormones in cardiomyocyte energy metabolism
HP:0004914
0.0499436884913
0.5
INSR
Recurrent infantile hypoglycemia
HP:0012684
0.0499436884913
0.5
INSR
Abnormal pineal volume
HP:0012686
0.0499436884913
0.5
INSR
Increased pineal volume
HP:0034384
0.0499436884913
0.5
INSR
Elevated circulating insulin:C-peptide ratio
Showing 1 to 9 of 9 entries
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Edges
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Protein 1
Protein 2
Score
?
ProteomeHD
?
Interface Overlap
?
Evidence
?
HSD17B2
INSR
0.98
bioplex3_WMM bioplex3_HCT116 WMM_only
HSD11B1
INSR
0.957
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116
Showing 1 to 2 of 2 entries
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Related Complexes
Genename
Complexes
HSD11B1
huMAP3_01368.1
huMAP3_04935.1
huMAP3_06561.1
huMAP3_09799.1
huMAP3_10145.1
huMAP3_11006.1
HSD17B2
huMAP3_01819.1
huMAP3_01871.1
huMAP3_02162.1
huMAP3_04738.1
huMAP3_04935.1
huMAP3_05317.1
huMAP3_06544.1
huMAP3_06842.1
huMAP3_07941.1
huMAP3_08232.1
huMAP3_08380.1
huMAP3_08471.1
huMAP3_09577.1
huMAP3_10255.1
huMAP3_10855.1
huMAP3_13451.1
huMAP3_14009.1
huMAP3_14690.1
INSR
huMAP3_02023.1
huMAP3_04935.1
huMAP3_06561.1
huMAP3_08471.1
huMAP3_11006.1