hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_04948.1
Complex Portal: CPX-18334
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| LYSMD1 | LysM and putative peptidoglycan-binding domain-containing protein 1 | 4 | UniProt NCBI |
| TUB | Tubby protein homolog | 5 | UniProt NCBI |
| RNF138 | E3 ubiquitin-protein ligase RNF138 (EC 2.3.2.27) (Nemo-like kinase-associated RING finger protein) (NLK-associated RING finger protein) (hNARF) (RING finger protein 138) (RING-type E3 ubiquitin transferase RNF138) | 5 | UniProt NCBI |
| TULP1 | Tubby-related protein 1 (Tubby-like protein 1) | 5 | UniProt NCBI |
| TULP3 | Tubby-related protein 3 (Tubby-like protein 3) | 5 | UniProt NCBI |
| GNL1 | Guanine nucleotide-binding protein-like 1 (GTP-binding protein HSR1) | 4 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0500087 | 0.00841070885474 | 0.333333333333 | TULP1 TUB | Peripapillary atrophy |
| HP:0012512 | 0.00981070246055 | 0.333333333333 | TULP1 TUB | Diffuse optic disc pallor |
| GO:0120160 | 0.0210651876021 | 0.333333333333 | TUB TULP3 | intraciliary transport particle A binding |
| GO:0061512 | 0.0421653429605 | 0.5 | TULP1 TUB TULP3 | protein localization to cilium |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| TULP1 | TULP3 | 0.997 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| LYSMD1 | TULP3 | 0.994 | 0.092 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| TUB | TULP3 | 0.98 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| GNL1 | TULP3 | 0.965 | 0.0768 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt_WMM | |
| RNF138 | TULP3 | 0.96 | 0.137111111111 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| LYSMD1 | TULP1 | 0.557 | bioplex_WMM bioplex3_WMM WMM_only | ||
| TUB | TULP1 | 0.487 | bioplex_WMM bioplex3_WMM WMM_only | ||
| LYSMD1 | TUB | 0.487 | bioplex_WMM bioplex3_WMM WMM_only | ||
| GNL1 | LYSMD1 | 0.172 | 0.128 | bioplex_WMM bioplex3_WMM WMM_only | |
| GNL1 | TULP1 | 0.172 | bioplex_WMM bioplex3_WMM WMM_only | ||
| RNF138 | TUB | 0.166 | bioplex_WMM bioplex3_WMM WMM_only | ||
| GNL1 | TUB | 0.164 | bioplex_WMM bioplex3_WMM WMM_only | ||
| RNF138 | LYSMD1 | 0.143 | 0.09 | bioplex_WMM bioplex3_WMM WMM_only | |
| RNF138 | TULP1 | 0.143 | bioplex_WMM bioplex3_WMM WMM_only | ||
| GNL1 | RNF138 | 0.032 | 0.108 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes