hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_04974.1
Complex Portal: CPX-17373
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| ST8SIA2 | Alpha-2,8-sialyltransferase 8B (EC 2.4.3.-) (Sialyltransferase 8B) (SIAT8-B) (Sialyltransferase St8Sia II) (ST8SiaII) (Sialyltransferase X) (STX) | 5 | UniProt NCBI |
| LDLR | Low-density lipoprotein receptor (LDL receptor) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP2846 | 0.0124400931326 | 0.5 | LDLR | PCSK9 mediated LDL receptor degradation |
| WP:WP3408 | 0.0124400931326 | 0.5 | LDLR | Evolocumab mechanism to reduce LDL cholesterol |
| WP:WP3601 | 0.049750157242 | 0.5 | LDLR | Lipid particles composition |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| ST8SIA2 | LDLR | 0.952 | bioplex3_WMM bioplex3_HCT116 WMM_only |
Related Complexes