hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_05053.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| EEFSEC | Selenocysteine-specific elongation factor (EC 3.6.5.-) (Elongation factor sec) (Eukaryotic elongation factor, selenocysteine-tRNA-specific) | 5 | UniProt NCBI |
| UTP14C | U3 small nucleolar RNA-associated protein 14 homolog C | 5 | UniProt NCBI |
| PNO1 | RNA-binding protein PNO1 (Partner of NOB1) | 5 | UniProt NCBI |
| UTP14A | U3 small nucleolar RNA-associated protein 14 homolog A (Antigen NY-CO-16) (Serologically defined colon cancer antigen 16) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-6790901 | 4.54859086639e-05 | 0.75 | PNO1 UTP14C UTP14A | rRNA modification in the nucleus and cytosol |
| REAC:R-HSA-6791226 | 0.00132908901162 | 0.75 | PNO1 UTP14C UTP14A | Major pathway of rRNA processing in the nucleolus and cytosol |
| REAC:R-HSA-8868773 | 0.00156371199708 | 0.75 | PNO1 UTP14C UTP14A | rRNA processing in the nucleus and cytosol |
| REAC:R-HSA-72312 | 0.00182434362823 | 0.75 | PNO1 UTP14C UTP14A | rRNA processing |
| KEGG:03008 | 0.00654897197861 | 0.5 | UTP14A UTP14C | Ribosome biogenesis in eukaryotes |
| GO:0032040 | 0.0228491864842 | 0.75 | PNO1 UTP14C UTP14A | small-subunit processome |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| UTP14A | PNO1 | 0.983 | 0.698 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM |
| EEFSEC | PNO1 | 0.98 | 0.028 | hein_WMM bioplex3_WMM youn_WMM WMM_only |
| UTP14C | PNO1 | 0.975 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM | |
| UTP14A | UTP14C | 0.904 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM WMM_only | |
| UTP14A | EEFSEC | 0.006 | 0.012 | youn_WMM WMM_only |
Related Complexes