hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_05057.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| MYH9 | Myosin-9 (Cellular myosin heavy chain, type A) (Myosin heavy chain 9) (Myosin heavy chain, non-muscle IIa) (Non-muscle myosin heavy chain A) (NMMHC-A) (Non-muscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) | 5 | UniProt NCBI |
| SYNPO | Synaptopodin | 5 | UniProt NCBI |
| MYH10 | Myosin-10 (Cellular myosin heavy chain, type B) (Myosin heavy chain 10) (Myosin heavy chain, non-muscle IIb) (Non-muscle myosin heavy chain B) (NMMHC-B) (Non-muscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04530 | 2.28801742777e-05 | 1.0 | MYH10 MYH9 SYNPO | Tight junction |
| WP:WP4758 | 0.000753202688136 | 0.666666666667 | MYH9 SYNPO | Nephrotic syndrome |
| REAC:R-HSA-416572 | 0.0011650518872 | 0.666666666667 | MYH10 MYH9 | Sema4D induced cell migration and growth-cone collapse |
| REAC:R-HSA-5625900 | 0.0011650518872 | 0.666666666667 | MYH10 MYH9 | RHO GTPases activate CIT |
| REAC:R-HSA-5627117 | 0.0011650518872 | 0.666666666667 | MYH10 MYH9 | RHO GTPases Activate ROCKs |
| REAC:R-HSA-5627123 | 0.00129444299395 | 0.666666666667 | MYH10 MYH9 | RHO GTPases activate PAKs |
| REAC:R-HSA-400685 | 0.00172341693863 | 0.666666666667 | MYH10 MYH9 | Sema4D in semaphorin signaling |
| WP:WP2572 | 0.00213615497188 | 0.666666666667 | MYH9 SYNPO | Primary focal segmental glomerulosclerosis FSGS |
| REAC:R-HSA-3928663 | 0.00221357222266 | 0.666666666667 | MYH10 MYH9 | EPHA-mediated growth cone collapse |
| GO:0001725 | 0.00238416149886 | 1.0 | MYH10 MYH9 SYNPO | stress fiber |
| GO:0097517 | 0.00238416149886 | 1.0 | MYH10 MYH9 SYNPO | contractile actin filament bundle |
| GO:0032432 | 0.00312476641535 | 1.0 | MYH10 MYH9 SYNPO | actin filament bundle |
| GO:0042641 | 0.00328922780564 | 1.0 | MYH10 MYH9 SYNPO | actomyosin |
| KEGG:04270 | 0.00346604271076 | 0.666666666667 | MYH10 MYH9 | Vascular smooth muscle contraction |
| GO:0097513 | 0.00421361424067 | 0.666666666667 | MYH10 MYH9 | myosin II filament |
| KEGG:04814 | 0.00988245105972 | 0.666666666667 | MYH10 MYH9 | Motor proteins |
| KEGG:05130 | 0.0102516009655 | 0.666666666667 | MYH10 MYH9 | Pathogenic Escherichia coli infection |
| REAC:R-HSA-373755 | 0.0116360425406 | 0.666666666667 | MYH10 MYH9 | Semaphorin interactions |
| KEGG:04810 | 0.01431202154 | 0.666666666667 | MYH10 MYH9 | Regulation of actin cytoskeleton |
| REAC:R-HSA-5625740 | 0.0220121799777 | 0.666666666667 | MYH10 MYH9 | RHO GTPases activate PKNs |
| REAC:R-HSA-2682334 | 0.02256145142 | 0.666666666667 | MYH10 MYH9 | EPH-Ephrin signaling |
| GO:0031032 | 0.0478331772413 | 1.0 | MYH10 MYH9 SYNPO | actomyosin structure organization |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| MYH9 | MYH10 | 0.973 | 0.507 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM hein () gupta_WMM boldt_WMM treiber_WMM |
| MYH9 | SYNPO | 0.969 | hein_WMM hein () | |
| SYNPO | MYH10 | 0.15 | hein_WMM hein () |
Related Complexes