hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_05064.1

Complex Portal: CPX-18578

Confidence: Extremely High

Genename	Protein Name	Uniprot Annotation Score	Links
PSMC2	26S proteasome regulatory subunit 7 (26S proteasome AAA-ATPase subunit RPT1) (Proteasome 26S subunit ATPase 2)	5	UniProt NCBI
PSMD10	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin) (p28(GANK))	5	UniProt NCBI
UCHL5	Ubiquitin carboxyl-terminal hydrolase isozyme L5 (UCH-L5) (EC 3.4.19.12) (Ubiquitin C-terminal hydrolase UCH37) (Ubiquitin thioesterase L5)	5	UniProt NCBI
PSMD5	26S proteasome non-ATPase regulatory subunit 5 (26S protease subunit S5 basic) (26S proteasome subunit S5B)	5	UniProt NCBI
ZFAND2B	AN1-type zinc finger protein 2B (Arsenite-inducible RNA-associated protein-like protein) (AIRAP-like protein)	5	UniProt NCBI
PSMC6	26S proteasome regulatory subunit 10B (26S proteasome AAA-ATPase subunit RPT4) (Proteasome 26S subunit ATPase 6) (Proteasome subunit p42)	5	UniProt NCBI
PSMC5	26S proteasome regulatory subunit 8 (26S proteasome AAA-ATPase subunit RPT6) (Proteasome 26S subunit ATPase 5) (Proteasome subunit p45) (Thyroid hormone receptor-interacting protein 1) (TRIP1) (p45/SUG)	5	UniProt NCBI
PSMC4	26S proteasome regulatory subunit 6B (26S proteasome AAA-ATPase subunit RPT3) (MB67-interacting protein) (MIP224) (Proteasome 26S subunit ATPase 4) (Tat-binding protein 7) (TBP-7)	5	UniProt NCBI
UBE3A	Ubiquitin-protein ligase E3A (EC 2.3.2.26) (E6AP ubiquitin-protein ligase) (HECT-type ubiquitin transferase E3A) (Human papillomavirus E6-associated protein) (Oncogenic protein-associated protein E6-AP) (Renal carcinoma antigen NY-REN-54)	5	UniProt NCBI
PSMD3	26S proteasome non-ATPase regulatory subunit 3 (26S proteasome regulatory subunit RPN3) (26S proteasome regulatory subunit S3) (Proteasome subunit p58)	5	UniProt NCBI
ADRM1	Proteasomal ubiquitin receptor ADRM1 (110 kDa cell membrane glycoprotein) (Gp110) (Adhesion-regulating molecule 1) (ARM-1) (Proteasome regulatory particle non-ATPase 13) (hRpn13) (Rpn13 homolog)	5	UniProt NCBI
PSMD4	26S proteasome non-ATPase regulatory subunit 4 (26S proteasome regulatory subunit RPN10) (26S proteasome regulatory subunit S5A) (Antisecretory factor 1) (AF) (ASF) (Multiubiquitin chain-binding protein)	5	UniProt NCBI
TMEM31	Transmembrane protein 31	2	UniProt NCBI
PSMD7	26S proteasome non-ATPase regulatory subunit 7 (26S proteasome regulatory subunit RPN8) (26S proteasome regulatory subunit S12) (Mov34 protein homolog) (Proteasome subunit p40)	5	UniProt NCBI
PSMD8	26S proteasome non-ATPase regulatory subunit 8 (26S proteasome regulatory subunit RPN12) (26S proteasome regulatory subunit S14) (p31)	5	UniProt NCBI
PSMD13	26S proteasome non-ATPase regulatory subunit 13 (26S proteasome regulatory subunit RPN9) (26S proteasome regulatory subunit S11) (26S proteasome regulatory subunit p40.5)	5	UniProt NCBI
PSMC3	26S proteasome regulatory subunit 6A (26S proteasome AAA-ATPase subunit RPT5) (Proteasome 26S subunit ATPase 3) (Proteasome subunit P50) (Tat-binding protein 1) (TBP-1)	5	UniProt NCBI
CCDC74A	Coiled-coil domain-containing protein 74A	2	UniProt NCBI
BAG1	BAG family molecular chaperone regulator 1 (BAG-1) (Bcl-2-associated athanogene 1)	5	UniProt NCBI
PSMD11	26S proteasome non-ATPase regulatory subunit 11 (26S proteasome regulatory subunit RPN6) (26S proteasome regulatory subunit S9) (26S proteasome regulatory subunit p44.5)	5	UniProt NCBI
STKLD1	Serine/threonine kinase-like domain-containing protein STKLD1 (Serine/threonine kinase-like domain-containing protein 1) (Sugen kinase 071)	4	UniProt NCBI
PSMD2	26S proteasome non-ATPase regulatory subunit 2 (26S proteasome regulatory subunit RPN1) (26S proteasome regulatory subunit S2) (26S proteasome subunit p97) (Protein 55.11) (Tumor necrosis factor type 1 receptor-associated protein 2)	5	UniProt NCBI
PSMC1	26S proteasome regulatory subunit 4 (P26s4) (26S proteasome AAA-ATPase subunit RPT2) (Proteasome 26S subunit ATPase 1)	5	UniProt NCBI
PSMD1	26S proteasome non-ATPase regulatory subunit 1 (26S proteasome regulatory subunit RPN2) (26S proteasome regulatory subunit S1) (26S proteasome subunit p112)	5	UniProt NCBI
PAAF1	Proteasomal ATPase-associated factor 1 (Protein G-16) (WD repeat-containing protein 71)	4	UniProt NCBI
CCDC74B	Coiled-coil domain-containing protein 74B	4	UniProt NCBI
PSMD6	26S proteasome non-ATPase regulatory subunit 6 (26S proteasome regulatory subunit RPN7) (26S proteasome regulatory subunit S10) (Breast cancer-associated protein SGA-113M) (Phosphonoformate immuno-associated protein 4) (Proteasome regulatory particle subunit p44S10) (p42A)	5	UniProt NCBI
PSMD12	26S proteasome non-ATPase regulatory subunit 12 (26S proteasome regulatory subunit RPN5) (26S proteasome regulatory subunit p55)	5	UniProt NCBI
PSMD14	26S proteasome non-ATPase regulatory subunit 14 (EC 3.4.19.-) (26S proteasome regulatory subunit RPN11) (26S proteasome-associated PAD1 homolog 1)	5	UniProt NCBI
CCDC92	Coiled-coil domain-containing protein 92 (Limkain beta-2)	5	UniProt NCBI
REX1BD	Required for excision 1-B domain-containing protein	4	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
GO:0005838	1.10768327921e-51	0.645161290323	PSMD1 PSMC6 PSMD14 PSMD10 PSMC3 PSMC4 PSMD8 ADRM1 PSMD2 PSMD11 PSMD4 PSMC5 PSMD6 PSMD13 PSMD7 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	proteasome regulatory particle
GO:0022624	1.10768327921e-51	0.645161290323	PSMD1 PSMC6 PSMD14 PSMD10 PSMC3 PSMC4 PSMD8 ADRM1 PSMD2 PSMD11 PSMD4 PSMC5 PSMD6 PSMD13 PSMD7 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	proteasome accessory complex
CORUM:32	3.28993119975e-51	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	PA700 complex
GO:0000502	4.18237862852e-45	0.709677419355	PAAF1 PSMD3 PSMD7 PSMD1 PSMC1 PSMD5 PSMD8 PSMD6 PSMD12 PSMD4 PSMD14 PSMD11 PSMD13 PSMC6 ZFAND2B ADRM1 PSMC2 PSMC3 PSMD10 PSMC4 PSMD2 PSMC5	proteasome complex
CORUM:193	1.33329503026e-43	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	PA700-20S-PA28 complex
GO:1905369	3.29410450622e-41	0.709677419355	PAAF1 PSMD3 PSMD7 PSMD1 PSMC1 PSMD5 PSMD8 PSMD6 PSMD12 PSMD4 PSMD14 PSMD11 PSMD13 PSMC6 ZFAND2B ADRM1 PSMC2 PSMC3 PSMD10 PSMC4 PSMD2 PSMC5	endopeptidase complex
REAC:R-HSA-1236978	2.80775260598e-39	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Cross-presentation of soluble exogenous antigens (endosomes)
REAC:R-HSA-211733	7.57874008099e-39	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Regulation of activated PAK-2p34 by proteasome mediated degradation
REAC:R-HSA-350562	1.22142089578e-38	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Regulation of ornithine decarboxylase (ODC)
REAC:R-HSA-75815	1.94511616873e-38	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Ubiquitin-dependent degradation of Cyclin D
REAC:R-HSA-349425	1.94511616873e-38	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Autodegradation of the E3 ubiquitin ligase COP1
REAC:R-HSA-180534	1.94511616873e-38	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Vpu mediated degradation of CD4
REAC:R-HSA-69601	1.94511616873e-38	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Ubiquitin Mediated Degradation of Phosphorylated Cdc25A
REAC:R-HSA-69610	1.94511616873e-38	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	p53-Independent DNA Damage Response
REAC:R-HSA-69613	1.94511616873e-38	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	p53-Independent G1/S DNA damage checkpoint
REAC:R-HSA-9604323	3.06263278133e-38	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Negative regulation of NOTCH4 signaling
REAC:R-HSA-450408	3.06263278133e-38	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	AUF1 (hnRNP D0) binds and destabilizes mRNA
REAC:R-HSA-180585	3.06263278133e-38	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Vif-mediated degradation of APOBEC3G
REAC:R-HSA-9762114	3.06263278133e-38	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2
REAC:R-HSA-169911	3.06263278133e-38	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Regulation of Apoptosis
REAC:R-HSA-8854050	4.77036749169e-38	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	FBXL7 down-regulates AURKA during mitotic entry and in early mitosis
REAC:R-HSA-5689603	5.3810328063e-38	0.677419354839	PSMD1 PSMC6 PSMD14 PSMD10 PSMC3 PSMC4 PSMD8 ADRM1 PSMD2 PSMD11 PSMD4 PSMD7 PSMC5 PSMD6 PSMD13 PSMD5 UCHL5 PSMD3 PSMD12 PSMC2 PSMC1	UCH proteinases
REAC:R-HSA-174113	7.35423474284e-38	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	SCF-beta-TrCP mediated degradation of Emi1
REAC:R-HSA-5362768	7.35423474284e-38	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Hh mutants are degraded by ERAD
REAC:R-HSA-8941858	7.35423474284e-38	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Regulation of RUNX3 expression and activity
REAC:R-HSA-4641257	7.35423474284e-38	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Degradation of AXIN
REAC:R-HSA-5387390	1.12268414976e-37	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Hh mutants abrogate ligand secretion
KEGG:03050	1.49641488021e-37	0.58064516129	PSMD1 PSMC6 PSMD14 PSMD6 PSMD3 PSMD8 ADRM1 PSMC4 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMD7 PSMC3 PSMD12 PSMC2 PSMC1	Proteasome
REAC:R-HSA-4641258	1.69786746738e-37	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Degradation of DVL
REAC:R-HSA-351202	1.69786746738e-37	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Metabolism of polyamines
REAC:R-HSA-69541	1.69786746738e-37	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Stabilization of p53
GO:1905368	1.90857642061e-37	0.709677419355	PAAF1 PSMD3 PSMD7 PSMD1 PSMC1 PSMD5 PSMD8 PSMD6 PSMD12 PSMD4 PSMD14 PSMD11 PSMD13 PSMC6 ZFAND2B ADRM1 PSMC2 PSMC3 PSMD10 PSMC4 PSMD2 PSMC5	peptidase complex
REAC:R-HSA-5676590	3.78162232628e-37	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	NIK-->noncanonical NF-kB signaling
REAC:R-HSA-5610780	3.78162232628e-37	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Degradation of GLI1 by the proteasome
REAC:R-HSA-5358346	3.78162232628e-37	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Hedgehog ligand biogenesis
REAC:R-HSA-5607761	5.57352561817e-37	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Dectin-1 mediated noncanonical NF-kB signaling
REAC:R-HSA-5610783	5.57352561817e-37	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Degradation of GLI2 by the proteasome
REAC:R-HSA-5610785	5.57352561817e-37	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	GLI3 is processed to GLI3R by the proteasome
REAC:R-HSA-5678895	5.57352561817e-37	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Defective CFTR causes cystic fibrosis
REAC:R-HSA-187577	8.14999236251e-37	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	SCF(Skp2)-mediated degradation of p27/p21
REAC:R-HSA-5658442	1.18276245815e-36	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Regulation of RAS by GAPs
REAC:R-HSA-174084	2.43796879763e-36	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Autodegradation of Cdh1 by Cdh1:APC/C
REAC:R-HSA-4608870	2.43796879763e-36	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Asymmetric localization of PCP proteins
REAC:R-HSA-1234176	2.43796879763e-36	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
REAC:R-HSA-69563	3.46461772781e-36	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	p53-Dependent G1 DNA Damage Response
REAC:R-HSA-69580	3.46461772781e-36	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	p53-Dependent G1/S DNA damage checkpoint
REAC:R-HSA-1169091	4.89182088273e-36	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Activation of NF-kappaB in B cells
REAC:R-HSA-8939902	4.89182088273e-36	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Regulation of RUNX2 expression and activity
WP:WP2359	5.31009119093e-36	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Parkin ubiquitin proteasomal system pathway
REAC:R-HSA-69615	6.8639846106e-36	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	G1/S DNA Damage Checkpoints
REAC:R-HSA-174154	6.8639846106e-36	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	APC/C:Cdc20 mediated degradation of Securin
REAC:R-HSA-8948751	1.32752279773e-35	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Regulation of PTEN stability and activity
REAC:R-HSA-68949	2.51054575454e-35	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Orc1 removal from chromatin
REAC:R-HSA-1234174	2.51054575454e-35	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Cellular response to hypoxia
REAC:R-HSA-69017	3.42517459905e-35	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	CDK-mediated phosphorylation and removal of Cdc6
REAC:R-HSA-174184	3.42517459905e-35	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Cdc20:Phospho-APC/C mediated degradation of Cyclin A
REAC:R-HSA-5619084	3.42517459905e-35	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	ABC transporter disorders
REAC:R-HSA-174178	4.6494211692e-35	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
REAC:R-HSA-179419	4.6494211692e-35	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint
REAC:R-HSA-9013694	6.28040303089e-35	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Signaling by NOTCH4
REAC:R-HSA-1168372	8.44337442518e-35	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Downstream signaling events of B Cell Receptor (BCR)
REAC:R-HSA-176409	8.44337442518e-35	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	APC/C:Cdc20 mediated degradation of mitotic proteins
REAC:R-HSA-176814	1.12992278773e-34	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins
REAC:R-HSA-2871837	1.12992278773e-34	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	FCERI mediated NF-kB activation
REAC:R-HSA-8852276	1.5053828521e-34	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	The role of GTSE1 in G2/M progression after G2 checkpoint
REAC:R-HSA-5632684	1.99695893995e-34	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Hedgehog 'on' state
WP:WP183	2.3391051403e-34	0.58064516129	PSMD1 PSMC6 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Proteasome degradation
REAC:R-HSA-9759194	2.63797784471e-34	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Nuclear events mediated by NFE2L2
REAC:R-HSA-176408	3.47061452828e-34	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Regulation of APC/C activators between G1/S and early anaphase
REAC:R-HSA-195253	5.9371577522e-34	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Degradation of beta-catenin by the destruction complex
REAC:R-HSA-5687128	5.9371577522e-34	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	MAPK6/MAPK4 signaling
REAC:R-HSA-69202	7.72166973152e-34	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Cyclin E associated events during G1/S transition
REAC:R-HSA-450531	1.00061878036e-33	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Regulation of mRNA stability by proteins that bind AU-rich elements
REAC:R-HSA-69656	1.29209327693e-33	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Cyclin A:Cdk2-associated events at S phase entry
REAC:R-HSA-1236974	1.66275446536e-33	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	ER-Phagosome pathway
REAC:R-HSA-453276	2.13260790946e-33	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Regulation of mitotic cell cycle
REAC:R-HSA-174143	2.13260790946e-33	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	APC/C-mediated degradation of cell cycle proteins
REAC:R-HSA-5668541	2.13260790946e-33	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	TNFR2 non-canonical NF-kB pathway
REAC:R-HSA-8878159	3.47434835221e-33	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Transcriptional regulation by RUNX3
REAC:R-HSA-202424	4.4139204956e-33	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Downstream TCR signaling
REAC:R-HSA-69052	5.59072106295e-33	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Switching of origins to a post-replicative state
REAC:R-HSA-5607764	5.59072106295e-33	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	CLEC7A (Dectin-1) signaling
REAC:R-HSA-4086400	7.06050648755e-33	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	PCP/CE pathway
REAC:R-HSA-382556	1.39828571339e-32	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	ABC-family proteins mediated transport
REAC:R-HSA-983705	2.17572758513e-32	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Signaling by the B Cell Receptor (BCR)
REAC:R-HSA-1236975	3.35118670191e-32	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Antigen processing-Cross presentation
REAC:R-HSA-9020702	4.14383824238e-32	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Interleukin-1 signaling
REAC:R-HSA-8878166	9.46544306572e-32	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Transcriptional regulation by RUNX2
REAC:R-HSA-9755511	1.15721542827e-31	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	KEAP1-NFE2L2 pathway
REAC:R-HSA-5610787	1.41176982544e-31	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Hedgehog 'off' state
REAC:R-HSA-202403	1.71873657311e-31	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	TCR signaling
REAC:R-HSA-2454202	4.46178185238e-31	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Fc epsilon receptor (FCERI) signaling
REAC:R-HSA-8939236	9.25627909058e-31	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	RUNX1 regulates transcription of genes involved in differentiation of HSCs
REAC:R-HSA-69239	1.86857484834e-30	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Synthesis of DNA
REAC:R-HSA-5621481	2.21834391868e-30	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	C-type lectin receptors (CLRs)
REAC:R-HSA-162909	5.11372292985e-30	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Host Interactions of HIV factors
REAC:R-HSA-446652	9.72115339297e-30	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Interleukin-1 family signaling
REAC:R-HSA-68867	1.13761800853e-29	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Assembly of the pre-replicative complex
REAC:R-HSA-69206	1.13761800853e-29	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	G1/S Transition
REAC:R-HSA-5358351	1.32956017601e-29	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Signaling by Hedgehog
REAC:R-HSA-6807070	2.44943468386e-29	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	PTEN Regulation
REAC:R-HSA-3858494	2.84496591685e-29	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Beta-catenin independent WNT signaling
REAC:R-HSA-5689880	4.17489692922e-29	0.645161290323	PSMD1 PSMC6 PSMD14 PSMD10 PSMC3 PSMC4 PSMD8 ADRM1 PSMD2 PSMD11 PSMD4 PSMC5 PSMD6 PSMD13 PSMD7 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Ub-specific processing proteases
REAC:R-HSA-5619115	5.90981271051e-29	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Disorders of transmembrane transporters
REAC:R-HSA-453279	1.37064686089e-28	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Mitotic G1 phase and G1/S transition
REAC:R-HSA-69002	1.37064686089e-28	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	DNA Replication Pre-Initiation
KEGG:05017	1.95377672666e-28	0.58064516129	PSMD1 PSMC6 PSMD14 PSMD6 PSMD3 PSMD8 ADRM1 PSMC4 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMD7 PSMC3 PSMD12 PSMC2 PSMC1	Spinocerebellar ataxia
REAC:R-HSA-5688426	3.77044214451e-28	0.677419354839	PSMD1 PSMC6 PSMD14 PSMD10 PSMC3 PSMC4 PSMD8 ADRM1 PSMD2 PSMD11 PSMD4 PSMD7 PSMC5 PSMD6 PSMD13 PSMD5 UCHL5 PSMD3 PSMD12 PSMC2 PSMC1	Deubiquitination
REAC:R-HSA-69242	6.63515521601e-28	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	S Phase
REAC:R-HSA-69481	6.63515521601e-28	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	G2/M Checkpoints
REAC:R-HSA-109581	1.57142713048e-27	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Apoptosis
REAC:R-HSA-9010553	1.57142713048e-27	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Regulation of expression of SLITs and ROBOs
REAC:R-HSA-69306	4.01912158634e-27	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	DNA Replication
REAC:R-HSA-9711123	1.09583684583e-26	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Cellular response to chemical stress
REAC:R-HSA-2467813	1.22105966846e-26	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Separation of Sister Chromatids
REAC:R-HSA-69275	2.07825373297e-26	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	G2/M Transition
REAC:R-HSA-453274	2.56020601377e-26	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Mitotic G2-G2/M phases
REAC:R-HSA-5357801	3.48555962425e-26	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Programmed Cell Death
REAC:R-HSA-157118	9.41015839851e-26	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Signaling by NOTCH
REAC:R-HSA-201681	1.25500610832e-25	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	TCF dependent signaling in response to WNT
REAC:R-HSA-376176	1.66646295595e-25	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Signaling by ROBO receptors
REAC:R-HSA-8878171	1.82992549162e-25	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Transcriptional regulation by RUNX1
KEGG:05169	1.98433666024e-25	0.58064516129	PSMD1 PSMC6 PSMD14 PSMD6 PSMD3 PSMD8 ADRM1 PSMC4 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMD7 PSMC3 PSMD12 PSMC2 PSMC1	Epstein-Barr virus infection
REAC:R-HSA-5673001	2.20344796662e-25	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	RAF/MAP kinase cascade
GO:0043161	3.09065538649e-25	0.709677419355	PSMD3 PSMD7 PSMD1 PSMC1 UCHL5 PSMD8 PSMD6 PSMD12 PSMD4 PSMD14 PSMD11 PSMD13 PSMC6 ZFAND2B ADRM1 PSMC2 PSMC3 PSMD10 PSMC4 PSMD2 PSMC5 UBE3A	proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0008540	3.12860401865e-25	0.354838709677	PSMD1 PSMC6 PSMD10 PSMC4 PSMD2 PSMD4 PSMC5 PSMC1 PSMC3 PSMD5 PSMC2	proteasome regulatory particle, base subcomplex
REAC:R-HSA-5684996	3.17740144004e-25	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	MAPK1/MAPK3 signaling
REAC:R-HSA-162906	4.54969694751e-25	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	HIV Infection
REAC:R-HSA-68882	5.43033507612e-25	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Mitotic Anaphase
REAC:R-HSA-983168	5.83784484312e-25	0.645161290323	PSMD1 PSMC6 PSMD14 PSMD10 PSMC3 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD6 PSMD13 UBE3A PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Antigen processing: Ubiquitination & Proteasome degradation
REAC:R-HSA-2555396	5.92893946126e-25	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Mitotic Metaphase and Anaphase
REAC:R-HSA-8951664	6.4706591275e-25	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Neddylation
REAC:R-HSA-1257604	9.95818013161e-25	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	PIP3 activates AKT signaling
REAC:R-HSA-5683057	4.70530526838e-24	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	MAPK family signaling cascades
REAC:R-HSA-9006925	1.58446207611e-23	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Intracellular signaling by second messengers
KEGG:05012	3.58932217509e-23	0.58064516129	PSMD1 PSMC6 PSMD14 PSMD6 PSMD3 PSMD8 ADRM1 PSMC4 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMD7 PSMC3 PSMD12 PSMC2 PSMC1	Parkinson disease
REAC:R-HSA-983169	3.79275612006e-23	0.645161290323	PSMD1 PSMC6 PSMD14 PSMD10 PSMC3 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD6 PSMD13 UBE3A PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Class I MHC mediated antigen processing & presentation
REAC:R-HSA-69620	4.31119018009e-23	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Cell Cycle Checkpoints
KEGG:05020	6.12912945598e-23	0.58064516129	PSMD1 PSMC6 PSMD14 PSMD6 PSMD3 PSMD8 ADRM1 PSMC4 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMD7 PSMC3 PSMD12 PSMC2 PSMC1	Prion disease
GO:0010498	6.58925745011e-23	0.709677419355	PSMD3 PSMD7 PSMD1 PSMC1 UCHL5 PSMD8 PSMD6 PSMD12 PSMD4 PSMD14 PSMD11 PSMD13 PSMC6 ZFAND2B ADRM1 PSMC2 PSMC3 PSMD10 PSMC4 PSMD2 PSMC5 UBE3A	proteasomal protein catabolic process
REAC:R-HSA-195721	1.44922275667e-22	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Signaling by WNT
KEGG:05016	3.92142406909e-22	0.58064516129	PSMD1 PSMC6 PSMD14 PSMD6 PSMD3 PSMD8 ADRM1 PSMC4 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMD7 PSMC3 PSMD12 PSMC2 PSMC1	Huntington disease
REAC:R-HSA-71291	6.91205905257e-22	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Metabolism of amino acids and derivatives
GO:0006511	1.81606772568e-21	0.709677419355	PSMD3 PSMD7 PSMD1 PSMC1 UCHL5 PSMD8 PSMD6 PSMD12 PSMD4 PSMD14 PSMD11 PSMD13 PSMC6 ZFAND2B ADRM1 PSMC2 PSMC3 PSMD10 PSMC4 PSMD2 PSMC5 UBE3A	ubiquitin-dependent protein catabolic process
GO:0019941	2.59902408809e-21	0.709677419355	PSMD3 PSMD7 PSMD1 PSMC1 UCHL5 PSMD8 PSMD6 PSMD12 PSMD4 PSMD14 PSMD11 PSMD13 PSMC6 ZFAND2B ADRM1 PSMC2 PSMC3 PSMD10 PSMC4 PSMD2 PSMC5 UBE3A	modification-dependent protein catabolic process
WP:WP2059	3.70282847835e-21	0.548387096774	PSMD1 PSMC6 PSMD14 PSMD6 PSMD3 PSMD8 ADRM1 PSMC4 PSMD2 PSMD4 PSMC5 PSMD13 PSMD7 PSMC3 PSMD12 PSMC2 PSMC1	Alzheimer 39 s disease and miRNA effects
WP:WP5124	3.70282847835e-21	0.548387096774	PSMD1 PSMC6 PSMD14 PSMD6 PSMD3 PSMD8 ADRM1 PSMC4 PSMD2 PSMD4 PSMC5 PSMD13 PSMD7 PSMC3 PSMD12 PSMC2 PSMC1	Alzheimer 39 s disease
GO:0043632	4.21401658709e-21	0.709677419355	PSMD3 PSMD7 PSMD1 PSMC1 UCHL5 PSMD8 PSMD6 PSMD12 PSMD4 PSMD14 PSMD11 PSMD13 PSMC6 ZFAND2B ADRM1 PSMC2 PSMC3 PSMD10 PSMC4 PSMD2 PSMC5 UBE3A	modification-dependent macromolecule catabolic process
KEGG:05014	1.02754398822e-20	0.58064516129	PSMD1 PSMC6 PSMD14 PSMD6 PSMD3 PSMD8 ADRM1 PSMC4 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMD7 PSMC3 PSMD12 PSMC2 PSMC1	Amyotrophic lateral sclerosis
REAC:R-HSA-5663202	1.05455301474e-20	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Diseases of signal transduction by growth factor receptors and second messengers
REAC:R-HSA-68886	2.36849478438e-20	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	M Phase
KEGG:05010	2.46963202524e-20	0.58064516129	PSMD1 PSMC6 PSMD14 PSMD6 PSMD3 PSMD8 ADRM1 PSMC4 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMD7 PSMC3 PSMD12 PSMC2 PSMC1	Alzheimer disease
REAC:R-HSA-449147	3.67746741742e-20	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Signaling by Interleukins
GO:0051603	1.76785160348e-19	0.709677419355	PSMD3 PSMD7 PSMD1 PSMC1 UCHL5 PSMD8 PSMD6 PSMD12 PSMD4 PSMD14 PSMD11 PSMD13 PSMC6 ZFAND2B ADRM1 PSMC2 PSMC3 PSMD10 PSMC4 PSMD2 PSMC5 UBE3A	proteolysis involved in protein catabolic process
KEGG:05022	8.71628419235e-19	0.58064516129	PSMD1 PSMC6 PSMD14 PSMD6 PSMD3 PSMD8 ADRM1 PSMC4 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMD7 PSMC3 PSMD12 PSMC2 PSMC1	Pathways of neurodegeneration - multiple diseases
REAC:R-HSA-422475	1.55488240643e-18	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Axon guidance
REAC:R-HSA-9675108	3.11622197957e-18	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Nervous system development
REAC:R-HSA-69278	8.13474464233e-18	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Cell Cycle, Mitotic
REAC:R-HSA-382551	1.04442169879e-17	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Transport of small molecules
REAC:R-HSA-1280218	1.80324793584e-17	0.645161290323	PSMD1 PSMC6 PSMD14 PSMD10 PSMC3 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD6 PSMD13 UBE3A PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Adaptive Immune System
GO:0030163	3.14629991262e-17	0.709677419355	PSMD3 PSMD7 PSMD1 PSMC1 UCHL5 PSMD8 PSMD6 PSMD12 PSMD4 PSMD14 PSMD11 PSMD13 PSMC6 ZFAND2B ADRM1 PSMC2 PSMC3 PSMD10 PSMC4 PSMD2 PSMC5 UBE3A	protein catabolic process
REAC:R-HSA-2262752	9.69555129647e-17	0.645161290323	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMC1 PSMD5 PSMD3 PSMD12 PSMC2 BAG1	Cellular responses to stress
REAC:R-HSA-8953897	1.1724449343e-16	0.645161290323	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMC1 PSMD5 PSMD3 PSMD12 PSMC2 BAG1	Cellular responses to stimuli
REAC:R-HSA-1280215	1.28777897248e-16	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Cytokine Signaling in Immune system
GO:0140535	1.54815715882e-16	0.709677419355	PAAF1 PSMD3 PSMD7 PSMD1 PSMC1 PSMD5 PSMD8 PSMD6 PSMD12 PSMD4 PSMD14 PSMD11 PSMD13 PSMC6 ZFAND2B ADRM1 PSMC2 PSMC3 PSMD10 PSMC4 PSMD2 PSMC5	intracellular protein-containing complex
REAC:R-HSA-1640170	4.01041977595e-16	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Cell Cycle
REAC:R-HSA-8953854	1.13582487224e-15	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Metabolism of RNA
CORUM:181	1.46083174546e-15	0.258064516129	PSMC6 PSMC4 PSMC2 PSMC5 PSMD13 PSMC3 PSMD4 PSMC1	26S proteasome
REAC:R-HSA-9824446	1.89517877104e-15	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Viral Infection Pathways
GO:0008541	4.65927652849e-15	0.225806451613	PSMD3 PSMD12 PSMD11 PSMD13 ADRM1 PSMD8 PSMD14	proteasome regulatory particle, lid subcomplex
GO:0009057	2.97311840604e-14	0.709677419355	PSMD3 PSMD7 PSMD1 PSMC1 UCHL5 PSMD8 PSMD6 PSMD12 PSMD4 PSMD14 PSMD11 PSMD13 PSMC6 ZFAND2B ADRM1 PSMC2 PSMC3 PSMD10 PSMC4 PSMD2 PSMC5 UBE3A	macromolecule catabolic process
GO:0006508	3.36209541481e-14	0.709677419355	PSMD3 PSMD7 PSMD1 PSMC1 UCHL5 PSMD8 PSMD6 PSMD12 PSMD4 PSMD14 PSMD11 PSMD13 PSMC6 ZFAND2B ADRM1 PSMC2 PSMC3 PSMD10 PSMC4 PSMD2 PSMC5 UBE3A	proteolysis
GO:1901565	3.50218360022e-14	0.709677419355	PSMD3 PSMD7 PSMD1 PSMC1 UCHL5 PSMD8 PSMD6 PSMD12 PSMD4 PSMD14 PSMD11 PSMD13 PSMC6 ZFAND2B ADRM1 PSMC2 PSMC3 PSMD10 PSMC4 PSMD2 PSMC5 UBE3A	organonitrogen compound catabolic process
REAC:R-HSA-1266738	7.05279388373e-14	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Developmental Biology
REAC:R-HSA-5663205	8.74703010964e-14	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Infectious disease
REAC:R-HSA-168249	1.4510838344e-13	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Innate Immune System
REAC:R-HSA-597592	1.47375291132e-13	0.677419354839	PSMD1 PSMC6 PSMD14 PSMD10 PSMC3 PSMC4 PSMD8 ADRM1 PSMD2 PSMD11 PSMD4 PSMD7 PSMC5 PSMD6 PSMD13 PSMD5 UCHL5 PSMD3 PSMD12 PSMC2 PSMC1	Post-translational protein modification
REAC:R-HSA-212436	2.03007733893e-12	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Generic Transcription Pathway
GO:0036402	2.72269483219e-12	0.193548387097	PSMC6 PSMC4 PSMC5 PSMC1 PSMC3 PSMC2	proteasome-activating activity
GO:1902494	4.1141541319e-12	0.741935483871	PAAF1 PSMD3 PSMD7 PSMD1 PSMC1 UCHL5 PSMD5 PSMD8 PSMD6 PSMD12 PSMD4 PSMD13 PSMD11 PSMD14 PSMC6 ZFAND2B ADRM1 PSMC2 PSMC3 PSMD10 PSMC4 PSMD2 PSMC5	catalytic complex
REAC:R-HSA-73857	1.50725554964e-11	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	RNA Polymerase II Transcription
GO:1901575	6.39397245004e-11	0.709677419355	PSMD3 PSMD7 PSMD1 PSMC1 UCHL5 PSMD8 PSMD6 PSMD12 PSMD4 PSMD14 PSMD11 PSMD13 PSMC6 ZFAND2B ADRM1 PSMC2 PSMC3 PSMD10 PSMC4 PSMD2 PSMC5 UBE3A	organic substance catabolic process
REAC:R-HSA-392499	1.04611288382e-10	0.677419354839	PSMD1 PSMC6 PSMD14 PSMD10 PSMC3 PSMC4 PSMD8 ADRM1 PSMD2 PSMD11 PSMD4 PSMD7 PSMC5 PSMD6 PSMD13 PSMD5 UCHL5 PSMD3 PSMD12 PSMC2 PSMC1	Metabolism of proteins
REAC:R-HSA-74160	1.46390963093e-10	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Gene expression (Transcription)
REAC:R-HSA-168256	1.22164950993e-09	0.645161290323	PSMD1 PSMC6 PSMD14 PSMD10 PSMC3 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD6 PSMD13 UBE3A PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Immune System
GO:1904813	1.40732162484e-09	0.322580645161	PSMD3 PSMD14 PSMD6 PSMD11 PSMD2 PSMD13 PSMD7 PSMC3 PSMC2 PSMD12	ficolin-1-rich granule lumen
REAC:R-HSA-1643685	1.65934977993e-09	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Disease
GO:0009056	6.63289784676e-09	0.709677419355	PSMD3 PSMD7 PSMD1 PSMC1 UCHL5 PSMD8 PSMD6 PSMD12 PSMD4 PSMD14 PSMD11 PSMD13 PSMC6 ZFAND2B ADRM1 PSMC2 PSMC3 PSMD10 PSMC4 PSMD2 PSMC5 UBE3A	catabolic process
REAC:R-HSA-162582	3.61493555807e-08	0.645161290323	PSMD1 PSMC6 PSMD14 PSMD10 PSMC3 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD6 PSMD13 PSMD5 UCHL5 PSMD3 PSMD12 PSMC2 PSMC1	Signal Transduction
REAC:R-HSA-1430728	3.78209698554e-08	0.612903225806	PSMD1 PSMC6 PSMD14 PSMD10 PSMD6 PSMC4 PSMD8 PSMD7 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMC3 PSMD5 PSMD3 PSMD12 PSMC2 PSMC1	Metabolism
GO:0101002	4.34818073763e-08	0.322580645161	PSMD3 PSMD14 PSMD6 PSMD11 PSMD2 PSMD13 PSMD7 PSMC3 PSMC2 PSMD12	ficolin-1-rich granule
REAC:R-HSA-6798695	1.96190980978e-07	0.354838709677	PSMD3 PSMD14 PSMD6 PSMD11 PSMD2 PSMD1 PSMD13 PSMD7 PSMC3 PSMC2 PSMD12	Neutrophil degranulation
GO:0034774	4.45609283722e-07	0.354838709677	PSMD3 PSMD14 PSMD6 PSMD11 PSMD2 PSMD1 PSMD13 PSMD7 PSMC3 PSMC2 PSMD12	secretory granule lumen
GO:0060205	4.80148097741e-07	0.354838709677	PSMD3 PSMD14 PSMD6 PSMD11 PSMD2 PSMD1 PSMD13 PSMD7 PSMC3 PSMC2 PSMD12	cytoplasmic vesicle lumen
GO:0031983	4.98307947602e-07	0.354838709677	PSMD3 PSMD14 PSMD6 PSMD11 PSMD2 PSMD1 PSMD13 PSMD7 PSMC3 PSMC2 PSMD12	vesicle lumen
GO:0005654	5.25270213979e-05	0.774193548387	PAAF1 PSMD3 PSMD7 PSMD1 PSMC1 UCHL5 PSMD5 PSMD8 BAG1 PSMD10 PSMD4 PSMD13 PSMD11 PSMD14 PSMC6 PSMD6 ADRM1 PSMC2 PSMC3 PSMD12 PSMC4 PSMD2 PSMC5 CCDC92	nucleoplasm
GO:1903050	0.000146583628163	0.258064516129	PSMC6 PSMD10 PSMC3 PSMC5 PSMD14 UBE3A UCHL5 PSMC2	regulation of proteolysis involved in protein catabolic process
GO:0043248	0.000172328178158	0.129032258065	PSMD5 PSMD10 PSMD11 ADRM1	proteasome assembly
GO:0019538	0.000179356242019	0.741935483871	PSMD3 PSMD7 PSMD1 PSMC1 UCHL5 PSMD8 PSMD6 BAG1 PSMD12 PSMD4 PSMD13 PSMD11 PSMD14 PSMC6 ZFAND2B ADRM1 PSMC2 PSMC3 PSMD10 PSMC4 PSMD2 PSMC5 UBE3A	protein metabolic process
GO:0031981	0.000214417618191	0.774193548387	PAAF1 PSMD3 PSMD7 PSMD1 PSMC1 UCHL5 PSMD5 PSMD8 BAG1 PSMD10 PSMD4 PSMD13 PSMD11 PSMD14 PSMC6 PSMD6 ADRM1 PSMC2 PSMC3 PSMD12 PSMC4 PSMD2 PSMC5 CCDC92	nuclear lumen
WP:WP4352	0.000557505020764	0.193548387097	PSMC6 PSMD12 PSMC4 PSMD7 PSMD13 PSMD8	Ciliary landscape
HPA:0570743	0.00118850664166	0.290322580645	PSMD3 PSMD10 PSMC3 PSMC6 PSMD7 PSMD2 PSMD1 UBE3A UCHL5	testis; cells in seminiferous ducts[High]
GO:0061136	0.00127876124566	0.225806451613	PSMC6 PSMD10 PSMC5 PSMD14 PSMC3 UCHL5 PSMC2	regulation of proteasomal protein catabolic process
GO:0030141	0.00232233129896	0.354838709677	PSMD3 PSMD14 PSMD6 PSMD11 PSMD2 PSMD1 PSMD13 PSMD7 PSMC3 PSMC2 PSMD12	secretory granule
HPA:0090163	0.00273384716929	0.387096774194	PSMD3 PSMC3 PSMD1 PSMD7 PSMD2 PSMC5 CCDC92 PSMD13 ADRM1 UBE3A PSMC2 PSMC1	cerebellum; Purkinje cells[High]
HPA:0100133	0.00304144759412	0.41935483871	PSMD3 PSMC3 PSMD1 PSMD8 ADRM1 PSMD4 PSMC5 CCDC92 PSMD13 UBE3A UCHL5 PSMC2 PSMC1	cerebral cortex; neuronal cells[High]
GO:0099503	0.00955622528665	0.354838709677	PSMD3 PSMD14 PSMD6 PSMD11 PSMD2 PSMD1 PSMD13 PSMD7 PSMC3 PSMC2 PSMD12	secretory vesicle
GO:1901564	0.0107955043838	0.741935483871	PSMD3 PSMD7 PSMD1 PSMC1 UCHL5 PSMD8 PSMD6 BAG1 PSMD12 PSMD4 PSMD13 PSMD11 PSMD14 PSMC6 ZFAND2B ADRM1 PSMC2 PSMC3 PSMD10 PSMC4 PSMD2 PSMC5 UBE3A	organonitrogen compound metabolic process
HPA:0010011	0.0119762444971	0.58064516129	PSMD1 PSMC6 REX1BD PSMD10 PSMC3 PSMC4 PSMD8 ADRM1 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMD7 UCHL5 PSMD3 PSMC2 PSMD14	adipose tissue; adipocytes[>=Low]
HPA:0010000	0.0119762444971	0.58064516129	PSMD1 PSMC6 REX1BD PSMD10 PSMC3 PSMC4 PSMD8 ADRM1 PSMD2 PSMD11 PSMD4 PSMC5 PSMD13 PSMD7 UCHL5 PSMD3 PSMC2 PSMD14	adipose tissue
HPA:0050011	0.0122305746408	0.483870967742	PSMD1 PSMC6 REX1BD PSMD3 PSMD8 ADRM1 PSMC4 PSMD2 PSMD4 PSMC5 PSMD13 PSMD7 PSMC3 PSMC2 PSMD14	breast; adipocytes[>=Low]
HPA:0460652	0.0127031076859	0.483870967742	PSMD1 PSMC4 REX1BD PSMC3 PSMC6 ADRM1 PSMD11 PSMD4 PSMD7 PSMC5 PSMD13 UBE3A UCHL5 PSMC2 PSMD14	skin 1; fibroblasts[>=Medium]
HPA:0250133	0.0164593605536	0.322580645161	PSMD1 PSMC6 PSMD3 PSMD7 PSMD2 PSMC2 PSMC5 PSMC3 UBE3A PSMD4	hippocampus; neuronal cells[High]
GO:0031974	0.0209280072899	0.774193548387	PAAF1 PSMD3 PSMD7 PSMD1 PSMC1 UCHL5 PSMD5 PSMD8 BAG1 PSMD10 PSMD4 PSMD13 PSMD11 PSMD14 PSMC6 PSMD6 ADRM1 PSMC2 PSMC3 PSMD12 PSMC4 PSMD2 PSMC5 CCDC92	membrane-enclosed lumen
GO:0043233	0.0209280072899	0.774193548387	PAAF1 PSMD3 PSMD7 PSMD1 PSMC1 UCHL5 PSMD5 PSMD8 BAG1 PSMD10 PSMD4 PSMD13 PSMD11 PSMD14 PSMC6 PSMD6 ADRM1 PSMC2 PSMC3 PSMD12 PSMC4 PSMD2 PSMC5 CCDC92	organelle lumen
GO:0070013	0.0209280072899	0.774193548387	PAAF1 PSMD3 PSMD7 PSMD1 PSMC1 UCHL5 PSMD5 PSMD8 BAG1 PSMD10 PSMD4 PSMD13 PSMD11 PSMD14 PSMC6 PSMD6 ADRM1 PSMC2 PSMC3 PSMD12 PSMC4 PSMD2 PSMC5 CCDC92	intracellular organelle lumen
WP:000000	0.0249819594681	0.774193548387	PSMD3 PSMD7 PSMD1 PSMC1 UCHL5 PSMD5 PSMD8 BAG1 PSMD10 PSMD4 PSMD13 PSMD11 PSMD14 PSMC6 PSMD6 ADRM1 PSMC2 UBE3A PSMC3 PSMD12 PSMC4 PSMD2 PSMC5 CCDC74A	WIKIPATHWAYS
WP:000000	0.0249819594681	0.774193548387	PSMD3 PSMD7 PSMD1 PSMC1 UCHL5 PSMD5 PSMD8 BAG1 PSMD10 PSMD4 PSMD13 PSMD11 PSMD14 PSMC6 PSMD6 ADRM1 PSMC2 UBE3A PSMC3 PSMD12 PSMC4 PSMD2 PSMC5 CCDC74A	WIKIPATHWAYS
HPA:0510652	0.0253490875026	0.451612903226	PSMD1 PSMC4 PSMD12 PSMC3 PSMC6 PSMD8 ADRM1 PSMD4 PSMD7 PSMC5 PSMD13 UBE3A UCHL5 PSMC2	soft tissue 2; fibroblasts[>=Medium]
HPA:0500651	0.029317700163	0.58064516129	PSMD1 PSMC4 REX1BD PSMD12 PSMC3 PSMC6 PSMD8 ADRM1 PSMD14 PSMD4 PSMD7 PSMC5 PSMD13 UBE3A UCHL5 PSMD3 PSMC2 PSMC1	soft tissue 1; fibroblasts[>=Low]
HPA:0130201	0.029337618759	0.677419354839	PSMD1 PSMC6 PSMD14 PSMD10 PSMC3 PSMC4 PSMD8 ADRM1 REX1BD PSMD2 PSMD11 PSMD4 PSMD7 PSMC5 CCDC92 PSMD13 UBE3A UCHL5 PSMD3 PSMC2 PSMD12	colon; endothelial cells[>=Low]
HPA:0351181	0.0314880340605	0.677419354839	PSMD1 PSMC6 PSMD14 PSMD10 PSMC3 PSMC4 PSMD8 ADRM1 PSMD2 PSMD4 PSMD7 PSMC5 CCDC92 PSMD13 UBE3A PSMC1 UCHL5 PSMD3 PSMD12 PSMC2 BAG1	pancreas; pancreatic endocrine cells[>=Low]
GO:0005829	0.0365164765023	0.741935483871	PSMD3 PSMD7 PSMD1 PSMC1 UCHL5 PSMD5 PSMD8 BAG1 PSMD10 PSMD4 PSMD13 PSMD11 PSMD14 PSMC6 PSMD6 ADRM1 PSMC2 PSMC3 PSMD12 PSMC4 PSMD2 PSMC5 UBE3A	cytosol
HPA:0570742	0.0377977098094	0.41935483871	PSMC4 PSMD10 PSMC3 PSMD3 PSMD7 PSMC6 PSMD2 PSMD1 PSMD13 UBE3A UCHL5 PSMD14 PSMD12	testis; cells in seminiferous ducts[>=Medium]
HPA:0170251	0.0463407633154	0.516129032258	PSMC6 REX1BD PSMD10 PSMC3 PSMC4 ADRM1 PSMD2 PSMD11 PSMD4 PSMD7 PSMD1 BAG1 UCHL5 UBE3A PSMC2 PSMD12	endometrium 2; cells in endometrial stroma[>=Low]

Edges

Protein 1	Protein 2	Score	ProteomeHD	Interface Overlap
PSMD8	PSMD13	1.0	0.988
PSMC2	PSMC5	1.0	0.99	structurally_consistent (dimer)
PSMC5	PSMD2	1.0	0.95
PSMC4	PSMD2	1.0	0.974
PSMC4	PSMD1	1.0	0.988	structurally_consistent (dimer)
PSMD2	PSMD14	1.0	0.974
PSMC5	PSMD1	1.0	0.988	structurally_consistent (dimer)
PSMC6	PSMD2	1.0	0.924
PSMC3	PSMC4	1.0	0.994
PSMD11	PSMD2	1.0	0.992
PSMD8	PSMD2	1.0	0.906
PSMC5	PSMC4	1.0	0.99	structurally_consistent (dimer)
PSMC3	PSMC5	1.0	0.998	structurally_consistent (P62333) structurally_consistent (dimer)
PSMC4	PSMD12	1.0	0.924
PSMC3	PSMD1	1.0	0.972	structurally_consistent (P62195)
PSMC6	PSMD12	1.0	0.9	structurally_consistent (dimer)
PSMC3	PSMC6	1.0	0.998	structurally_consistent (dimer)
PSMC2	PSMC4	1.0	0.994
PSMD10	PAAF1	1.0	0.096	structurally_consistent (dimer)
PSMC5	PSMD3	1.0	0.976
PSMC6	PSMC5	1.0	0.998	structurally_consistent (dimer)
PSMD8	PSMD12	1.0	0.98
PSMD4	PSMD11	1.0	0.976	structurally_consistent (dimer)
PSMD13	PSMD14	1.0	0.976
PSMD13	PSMD2	1.0	0.974
PSMC5	PSMD12	1.0	0.97
PSMC5	PSMD11	1.0	0.986
PSMD5	PAAF1	1.0	0.104
PSMC3	PSMD2	1.0	0.922
PSMD4	PSMD13	1.0	0.876
PSMC2	PSMD2	1.0	0.994	structurally_consistent (dimer)
PSMD7	PSMD1	1.0	0.988
PSMC1	PSMC2	1.0	0.998
PSMD2	PSMD6	1.0	0.878
PSMD3	PSMD11	1.0	0.994	structurally_consistent (dimer)
PSMD7	PSMD12	1.0	0.992	structurally_consistent (dimer)
PSMD1	PSMD12	1.0	0.978	structurally_consistent (O43242)
PSMD4	PSMD2	1.0	0.836
PSMD7	PSMD14	1.0	0.984
PSMC1	PSMC5	1.0	0.986
PSMC6	PSMC4	1.0	0.99
PSMD2	PSMD12	1.0	0.984
PSMD7	PSMD13	1.0	0.994	structurally_consistent (dimer)
PSMD11	PSMD12	1.0	0.992	structurally_consistent (dimer)
PSMC4	PSMD14	1.0	0.98
PSMD3	PSMD6	1.0	0.99	structurally_consistent (dimer)
PSMD7	PSMD11	1.0	0.998
PSMC2	PSMD12	1.0	0.95
PSMD13	PSMD1	1.0	0.98
PSMC5	PSMD13	1.0	0.968
PSMC3	PSMD11	1.0	0.894
PSMD13	PSMD12	1.0	0.994	structurally_consistent (dimer)
PSMD3	PSMD1	1.0	0.994	structurally_consistent (dimer)
PSMC5	PSMD6	1.0	0.938
PSMC5	PSMD14	1.0	0.98
PSMD3	PSMD14	1.0	0.982	structurally_consistent (O00231)
PSMC3	PSMC2	1.0	0.952	structurally_consistent (P62333)
PSMC6	PSMD13	1.0	0.996	structurally_consistent (O00232)
PSMC2	PSMD1	1.0	0.942	structurally_consistent (P62195)
PSMD4	PSMD12	1.0	0.832	structurally_consistent (P51665)
PSMD7	PSMD8	1.0	0.978
PSMD12	PSMD14	1.0	0.988
PSMD4	PSMD14	1.0	0.884	structurally_consistent (O00231)
PSMC1	PSMC4	1.0	0.99	structurally_consistent (dimer)
PSMD13	PSMD11	1.0	0.994	structurally_consistent (dimer)
PSMC4	PSMD13	1.0	0.986	structurally_consistent (O00231)
PSMD2	PSMD1	1.0	0.956
PSMD3	PSMD7	1.0	1.0	structurally_consistent (dimer)
PSMD10	PSMD14	1.0	0.214
PSMD1	PSMD14	1.0	0.99	structurally_consistent (dimer)
PSMD11	PSMD1	1.0	0.988	structurally_consistent (O00487)
PSMC4	PSMD11	1.0	0.99	structurally_consistent (dimer)
PSMC6	PSMD1	1.0	0.992
PSMD3	PSMD13	1.0	0.994
PSMD8	PSMD14	1.0	0.966
PSMC1	PSMC3	1.0	0.976	structurally_consistent (dimer)
PSMC6	PSMD4	1.0	0.952	structurally_consistent (Q99933)
PSMD3	PSMD12	1.0	0.996	structurally_consistent (dimer)
PSMC4	PSMD3	1.0	0.976
PSMC2	PSMD4	1.0	0.894
PSMC5	PSMD4	1.0	0.946
PSMC1	PSMD2	1.0	0.994	structurally_consistent (dimer)
UCHL5	PSMC4	1.0	0.765133333333	mutually_exclusive (O75832)
PSMD10	PSMD4	1.0	0.318	structurally_consistent (dimer)
PSMC3	PSMD3	1.0	0.958
PSMD3	PSMD2	1.0	0.994
PSMD11	PSMD14	1.0	0.992	structurally_consistent (dimer)
PSMC2	PSMD13	1.0	0.996
PSMC6	PSMD11	1.0	0.994
PSMD7	PSMD2	1.0	0.946
PSMC4	PSMD8	1.0	0.998
PSMC1	PSMD8	1.0	0.946
PSMC3	PSMD14	1.0	0.986
PSMC3	PSMD8	1.0	0.95
PSMC5	PSMD7	1.0	0.986
PSMC1	PSMD13	1.0	0.992
PSMD10	PSMD2	1.0	0.456
PSMC3	PSMD13	1.0	0.87
PSMD4	PSMD8	1.0	0.828
PSMD11	PSMD6	1.0	0.98	structurally_consistent (dimer)
PSMD7	PSMD6	1.0	0.968
PSMC2	PSMD14	1.0	0.986	mutually_exclusive (Q16401)
PSMD4	PSMD1	1.0	0.97
PSMD1	PSMD6	1.0	0.978	structurally_consistent (O43242)
ZFAND2B	PSMC6	1.0	0.432
UCHL5	ADRM1	1.0	0.411875	structurally_consistent (dimer)
PSMD6	CCDC92	1.0	0.328
PSMD4	PAAF1	1.0	0.308
PSMD6	PSMD12	1.0	0.97	structurally_consistent (dimer)
PSMC1	PSMD4	1.0	0.972
ZFAND2B	TMEM31	1.0
PSMD10	PSMC5	1.0	0.49
PSMD1	CCDC92	1.0	0.104
UCHL5	PSMD6	1.0	0.7578	structurally_consistent (dimer)
PSMD10	PSMC4	1.0	0.552	structurally_consistent (dimer)
PSMD13	PSMD6	1.0	0.984	mutually_exclusive (Q9UL46) structurally_consistent (dimer)
PSMD3	PSMD4	1.0	0.87
PSMD10	PSMD5	1.0	0.474
PSMD3	PSMD8	1.0	0.988	structurally_consistent (dimer)
PSMC1	PSMD1	1.0	0.882
PSMD8	PSMD6	1.0	0.944	mutually_exclusive (Q9BRP4)
PSMC2	PSMC6	1.0	0.996	structurally_consistent (dimer)
PSMD14	CCDC92	1.0	0.333571428571
PSMD10	PSMD13	0.999	0.458	structurally_consistent (dimer)
PSMD4	CCDC92	0.999	0.228
PSMC6	PSMD14	0.999	0.988
UCHL5	PSMD7	0.999	0.446
PSMD7	PAAF1	0.999	0.234
PSMC3	CCDC92	0.999	0.358	structurally_consistent (dimer)
PSMD10	PSMD11	0.999	0.552
PSMC6	CCDC92	0.999	0.306
PSMC3	PSMD7	0.999	0.992
PSMC4	CCDC92	0.999	0.3
PSMC4	PSMD4	0.999	0.972
PSMC6	PSMD3	0.999	0.996
PSMD10	PSMD8	0.999	0.53	structurally_consistent (dimer)
PSMD6	PSMD14	0.999	0.962	structurally_consistent (O00231)
PSMD7	CCDC92	0.999	0.298
PSMC5	PAAF1	0.999	0.326
PSMD8	PSMD1	0.999	0.974	structurally_consistent (dimer)
UCHL5	PSMD1	0.999	0.588
PSMC4	PSMD6	0.999	0.918
PSMD10	UBE3A	0.999	0.152	structurally_consistent (dimer)
PSMC5	PSMD8	0.999	0.922
PSMC4	PAAF1	0.999	0.282
PSMC2	PSMD8	0.999	0.962
PSMD3	PAAF1	0.999	0.266	mutually_exclusive (P48556)
PSMD10	PSMC6	0.999	0.56
PSMC6	PSMD6	0.999	0.948
PSMC2	PSMD3	0.999	0.966
PSMC3	PSMD12	0.999	0.868
PSMC1	PSMD7	0.999	0.972
PSMD4	PSMD7	0.999	0.888	structurally_consistent (dimer)
PSMD8	CCDC92	0.999	0.234
PSMC2	PSMD7	0.999	0.994
PSMC1	PSMD14	0.999	0.98
PSMD5	PSMD1	0.999	0.388
PSMD10	PSMD3	0.999	0.512	structurally_consistent (O00232)
UCHL5	PSMD11	0.999	0.670894736842
PSMD10	PSMD1	0.999	0.486
PSMD11	CCDC92	0.999	0.317714285714
PSMC2	CCDC92	0.999	0.238
UCHL5	PSMC5	0.999	0.7038
PSMC2	PSMD5	0.999	0.524	structurally_consistent (dimer)
PSMD4	PSMD6	0.999	0.822	structurally_consistent (dimer)
ZFAND2B	PSMC5	0.999	0.3
PSMD10	CCDC92	0.999	0.114
PSMC3	PSMD6	0.999	0.936
PSMC6	PSMD7	0.999	0.984
UCHL5	PSMD12	0.999	0.484941176471
ADRM1	PSMD12	0.999	0.73	structurally_consistent (O75832)
UCHL5	PSMD2	0.999	0.409
PSMC4	PSMD7	0.999	0.986
PAAF1	PSMD14	0.999	0.17
PSMD10	PSMD12	0.999	0.386	structurally_consistent (dimer)
PSMD8	PSMD11	0.999	0.994
PSMC5	CCDC92	0.999	0.324
PSMC1	PSMD3	0.999	0.97
PSMC1	PSMD12	0.999	0.962
PSMC5	ADRM1	0.999	0.924
PSMC1	PSMD6	0.999	0.924
PSMC2	PSMD11	0.999	0.994
PSMD5	PSMD11	0.999	0.654	structurally_consistent (dimer)
PSMC2	PSMD10	0.999	0.536
PSMD2	CCDC92	0.999	0.22
PSMD3	CCDC92	0.999	0.306
PSMC2	UCHL5	0.999	0.489466666667	mutually_exclusive (Q16401)
UCHL5	PAAF1	0.999	0.082	structurally_consistent (O75832)
ZFAND2B	PSMC3	0.999	0.356
PSMD5	ADRM1	0.999	0.374
PSMC3	PSMD10	0.999	0.476
PSMC1	CCDC92	0.999	0.302
PSMC4	ADRM1	0.999	0.964	structurally_consistent (O75832)
ZFAND2B	PSMC4	0.999	0.362	mutually_exclusive (O75832)
PSMD13	CCDC92	0.999	0.124
UCHL5	PSMC6	0.999	0.707333333333
PSMC4	CCDC74B	0.999
PSMD13	PAAF1	0.999	0.078
PAAF1	PSMD12	0.999	0.112	structurally_consistent (O75832)
PSMC1	PSMD10	0.999	0.572
PSMD5	PSMD3	0.998	0.56
PSMD3	CCDC74B	0.998
PSMD7	CCDC74B	0.998
PSMD5	PSMC6	0.998	0.738	structurally_consistent (dimer)
PSMC3	CCDC74B	0.998		structurally_consistent (dimer)
PSMC2	PSMD6	0.998	0.922
ADRM1	PSMD8	0.998	0.902
UCHL5	PSMD14	0.998	0.652739495798
ADRM1	PSMD14	0.998	0.904
PSMC1	PSMC6	0.998	0.994
PSMC5	CCDC74B	0.998
PSMD1	PAAF1	0.998	0.224
PSMC3	PSMD5	0.998	0.698	structurally_consistent (dimer)
CCDC74B	PSMD12	0.998		structurally_consistent (O75832)
PSMD10	ADRM1	0.998	0.164	structurally_consistent (dimer)
ADRM1	PSMD13	0.998	0.84
ZFAND2B	PSMD14	0.998	0.182
PSMD7	REX1BD	0.998	0.186
ZFAND2B	PSMD6	0.998	0.194	structurally_consistent (dimer)
CCDC74B	PSMD14	0.998
PSMD5	PSMD4	0.998	0.372
PSMC2	CCDC74B	0.998
PSMC6	CCDC74B	0.998		mutually_exclusive (P17980)
PSMD10	PSMD6	0.998	0.534
PSMD5	PSMC5	0.998	0.62	structurally_consistent (dimer)
PSMD5	PSMD14	0.998	0.564	structurally_consistent (dimer)
BAG1	PSMC6	0.998	0.4999	structurally_consistent (dimer)
PSMC6	PSMD8	0.998	0.976
PSMC1	PSMD11	0.998	1.0
BAG1	PSMC5	0.998	0.523368421053
PSMC1	PSMD5	0.998	0.666	structurally_consistent (dimer)
PSMD11	CCDC74B	0.998
ADRM1	PSMD6	0.998	0.816
UBE3A	PSMD4	0.998	0.216	mutually_exclusive (O75832)
PSMD1	CCDC74B	0.998
PSMD12	CCDC92	0.998	0.172705882353
PSMD5	PSMD13	0.998	0.336
PSMD8	PAAF1	0.998	0.126	structurally_consistent (O75832) structurally_consistent (dimer)
PSMD5	PSMD2	0.998	0.462
PSMD5	PSMD12	0.998	0.656
ADRM1	PSMD7	0.998	0.916	structurally_consistent (dimer)
BAG1	PSMC1	0.998	0.476
PSMD5	PSMC4	0.998	0.41
PSMD8	CCDC74B	0.998		structurally_consistent (dimer)
PSMD11	PAAF1	0.998	0.456
BAG1	PSMD10	0.997	0.134	structurally_consistent (dimer)
UCHL5	PSMD13	0.997	0.537466666667	structurally_consistent (Q15008)
PSMD2	PAAF1	0.997	0.138
PSMC1	UCHL5	0.997	0.590138888889	mutually_exclusive (Q16401)
PSMD5	PSMD6	0.997	0.722
PSMC6	PAAF1	0.997	0.384
ADRM1	CCDC74B	0.997
ZFAND2B	PSMD12	0.997	0.180805970149	mutually_exclusive (O75832)
PSMC3	ADRM1	0.997	0.908
ADRM1	PSMD11	0.997	0.824
ZFAND2B	PSMC1	0.997	0.43
ZFAND2B	PSMD8	0.997	0.184	mutually_exclusive (O75832)
PSMC3	PSMD4	0.997	0.98
PSMC1	CCDC74B	0.997
UCHL5	PSMD3	0.997	0.636
ZFAND2B	PSMD1	0.997	0.284
CCDC74A	ZFAND2B	0.997
CCDC74B	PSMD6	0.997
ADRM1	PAAF1	0.996	0.098
PSMD10	UCHL5	0.996	0.124	structurally_consistent (dimer)
ZFAND2B	PSMD13	0.996	0.216	mutually_exclusive (Q15008)
PSMC3	UCHL5	0.996	0.714
PSMD5	PSMD8	0.996	0.608
ZFAND2B	PSMD7	0.996	0.196
ZFAND2B	PSMD11	0.996	0.18	mutually_exclusive (Q15008)
PSMD4	CCDC74B	0.996
PSMD13	REX1BD	0.996	0.428
PSMC1	PAAF1	0.995	0.392
PSMD2	CCDC74B	0.995
PSMD5	PSMD7	0.995	0.696
ADRM1	CCDC92	0.995	0.078
BAG1	PSMD2	0.995	0.5355
PSMD3	ADRM1	0.995	0.774	mutually_exclusive (P51665)
BAG1	PAAF1	0.995	0.1
PSMD13	CCDC74B	0.995
PSMC2	PAAF1	0.995	0.21
ZFAND2B	PSMD3	0.994	0.280727272727
UCHL5	PSMD8	0.994	0.5305	mutually_exclusive (O75832)
PSMC2	ADRM1	0.994	0.96
PAAF1	PSMD6	0.993	0.292	structurally_consistent (dimer)
PSMD14	REX1BD	0.993	0.17
UCHL5	PSMD4	0.993	0.704	mutually_exclusive (O75832)
PSMD10	PSMD7	0.993	0.608
ZFAND2B	PSMD2	0.993	0.178
PSMC6	ADRM1	0.992	0.95
BAG1	UCHL5	0.992	0.088	mutually_exclusive (O75832)
CCDC74A	CCDC74B	0.992		mutually_exclusive (P17980)
PSMC3	PAAF1	0.992	0.428857142857
UCHL5	CCDC92	0.992	0.066
UBE3A	PSMD12	0.992	0.19	mutually_exclusive (O75832)
BAG1	PSMD6	0.991	0.464
UBE3A	PSMD14	0.99	0.214
ADRM1	PSMD2	0.99	0.844
TMEM31	PSMC6	0.99
UBE3A	PSMD13	0.99	0.358
ZFAND2B	PSMD10	0.989	0.13	structurally_consistent (dimer)
STKLD1	PSMC3	0.989
TMEM31	PSMC3	0.988
ZFAND2B	PSMC2	0.988	0.302
BAG1	PSMC2	0.988	0.558666666667
PSMC4	UBE3A	0.987	0.188	mutually_exclusive (O75832)
PSMC1	UBE3A	0.987	0.242
PSMC1	ADRM1	0.986	0.934
ADRM1	PSMD4	0.986	0.902
UCHL5	CCDC74B	0.986
ZFAND2B	PAAF1	0.985	0.08	structurally_consistent (O75832)
UBE3A	CCDC92	0.985	0.188
BAG1	PSMC3	0.985	0.62
BAG1	ADRM1	0.984	0.238	structurally_consistent (O75832)
BAG1	PSMD12	0.982	0.412
BAG1	PSMD8	0.982	0.212
CCDC74A	ADRM1	0.982
STKLD1	PSMD12	0.982
ADRM1	PSMD1	0.98	0.92	structurally_consistent (dimer)
TMEM31	ADRM1	0.98
UBE3A	PSMD7	0.98	0.152
PSMD10	REX1BD	0.98	0.088
TMEM31	PSMD2	0.98
TMEM31	PSMD12	0.98
PSMD3	REX1BD	0.98	0.198
PSMC6	UBE3A	0.98	0.24
BAG1	PSMD1	0.979	0.602	structurally_consistent (P43686)
UBE3A	PSMD2	0.978	0.352
TMEM31	PSMD6	0.978
TMEM31	PSMD1	0.977
TMEM31	PSMD10	0.977
TMEM31	PSMD8	0.976
PSMC4	REX1BD	0.976	0.24
PSMD12	REX1BD	0.976	0.272
TMEM31	PSMD3	0.976
TMEM31	PSMD14	0.976
TMEM31	PSMC2	0.975
TMEM31	PSMD13	0.974
UBE3A	PSMD1	0.973	0.358
BAG1	PSMC4	0.973	0.372	structurally_consistent (dimer)
PSMD10	CCDC74B	0.972		structurally_consistent (dimer)
PSMD8	REX1BD	0.972	0.31
TMEM31	PSMC5	0.972
TMEM31	UCHL5	0.966
PSMC2	REX1BD	0.964	0.168
TMEM31	PSMC4	0.962
TMEM31	PSMD4	0.962
ADRM1	REX1BD	0.961	0.1
TMEM31	PSMC1	0.961
UBE3A	PSMD11	0.96	0.212
PAAF1	CCDC92	0.96	0.028
UBE3A	PSMD6	0.959	0.33
UBE3A	PSMD8	0.959	0.202	mutually_exclusive (O75832)
TMEM31	PSMD7	0.959
UBE3A	ADRM1	0.959	0.288
BAG1	PSMD11	0.958	0.55	structurally_consistent (dimer)
PAAF1	CCDC74B	0.958		mutually_exclusive (P48556)
PSMC1	REX1BD	0.957	0.196
PSMD2	REX1BD	0.957	0.168
ZFAND2B	UCHL5	0.957	0.084
CCDC74A	PSMD10	0.956
BAG1	PSMD3	0.955	0.459625
CCDC74A	PSMD13	0.955
PSMC3	REX1BD	0.955	0.244
TMEM31	PSMD11	0.955
UCHL5	PSMD5	0.955	0.2935	structurally_consistent (dimer)
PSMD1	REX1BD	0.954	0.22
PSMC5	REX1BD	0.954	0.348
CCDC74A	PSMD6	0.952
CCDC74A	PSMC3	0.951		structurally_consistent (dimer)
CCDC74A	PSMC2	0.951
BAG1	PSMD4	0.951	0.380603015075	mutually_exclusive (O75832) structurally_consistent (dimer)
PSMD4	REX1BD	0.951	0.238
PSMC5	UBE3A	0.95	0.274
TMEM31	CCDC92	0.95
ZFAND2B	PSMD4	0.95	0.300666666667
CCDC74A	PSMC6	0.948		mutually_exclusive (P17980)
CCDC74A	PSMD5	0.947		structurally_consistent (P17980)
CCDC74A	PSMD1	0.945
ZFAND2B	UBE3A	0.945	0.108	mutually_exclusive (O75832)
CCDC74A	PSMD12	0.945
CCDC74A	PSMD2	0.942
ZFAND2B	ADRM1	0.939	0.11
PAAF1	REX1BD	0.934	0.078
UBE3A	PSMD3	0.933	0.226
CCDC74A	PSMD7	0.932
PSMC2	UBE3A	0.931	0.28
CCDC74A	PSMD14	0.93
CCDC74A	PSMD11	0.93
PSMC6	REX1BD	0.929	0.348
BAG1	PSMD13	0.926	0.288	mutually_exclusive (O75832)
BAG1	PSMD7	0.925	0.4805
CCDC74A	PSMD8	0.924
CCDC74A	PSMD3	0.924
CCDC74A	PSMD4	0.921
CCDC74A	PSMC4	0.92
PSMD11	REX1BD	0.919	0.238
CCDC74A	PSMC1	0.913		structurally_consistent (P17980)
PSMD6	REX1BD	0.91	0.234
CCDC74A	PSMC5	0.908
BAG1	PSMD14	0.875	0.522	structurally_consistent (O00231)
UBE3A	PAAF1	0.857	0.116	structurally_consistent (O75832)
PSMD5	CCDC92	0.851	0.134	structurally_consistent (P17980)
PSMC3	UBE3A	0.827	0.198
BAG1	PSMD5	0.798	0.386
CCDC74A	UCHL5	0.777
PSMD5	UBE3A	0.764	0.184
UBE3A	REX1BD	0.755	0.068
PSMD5	REX1BD	0.65	0.12
STKLD1	PSMD4	0.586
UCHL5	UBE3A	0.457	0.1	mutually_exclusive (O75832)
CCDC74A	PAAF1	0.363
STKLD1	PSMD14	0.294
STKLD1	ADRM1	0.289
BAG1	CCDC92	0.281	0.088
STKLD1	PSMD1	0.276
PSMC1	STKLD1	0.276
STKLD1	PSMC4	0.276
STKLD1	PSMC2	0.276
UCHL5	REX1BD	0.26	0.132
STKLD1	PSMD10	0.257
STKLD1	UCHL5	0.219
STKLD1	PAAF1	0.215
STKLD1	PSMC5	0.215
STKLD1	PSMD2	0.215
STKLD1	PSMD6	0.215
STKLD1	PSMD11	0.215
STKLD1	PSMD3	0.215
ZFAND2B	PSMD5	0.213	0.242
STKLD1	PSMC6	0.205
STKLD1	PSMD13	0.205
STKLD1	PSMD8	0.2
BAG1	UBE3A	0.179	0.16
STKLD1	CCDC92	0.164
STKLD1	PSMD7	0.142
PSMD5	CCDC74B	0.131
TMEM31	UBE3A	0.119
CCDC92	REX1BD	0.076	0.126
ZFAND2B	CCDC92	0.064	0.064
BAG1	REX1BD	0.057	0.082
STKLD1	PSMD5	0.046
ZFAND2B	CCDC74B	0.043
STKLD1	UBE3A	0.042
CCDC74A	UBE3A	0.03
TMEM31	PSMD5	0.02
UBE3A	CCDC74B	0.013

Related Complexes

Genename	Complexes
PSMC2	huMAP3_05064.1 huMAP3_09656.1 huMAP3_13725.1
PSMD10	huMAP3_05064.1 huMAP3_09656.1 huMAP3_13725.1
UCHL5	huMAP3_05064.1 huMAP3_09656.1 huMAP3_13725.1 huMAP3_14133.1 huMAP3_15233.1
PSMD5	huMAP3_05064.1 huMAP3_09656.1 huMAP3_13725.1
ZFAND2B	huMAP3_00331.1 huMAP3_05064.1 huMAP3_09656.1 huMAP3_11052.1 huMAP3_12138.1 huMAP3_13725.1
PSMC6	huMAP3_05064.1 huMAP3_09656.1 huMAP3_13725.1
PSMC5	huMAP3_05064.1 huMAP3_09656.1 huMAP3_13725.1
PSMC4	huMAP3_05064.1 huMAP3_09656.1 huMAP3_13725.1
UBE3A	huMAP3_05064.1 huMAP3_09656.1 huMAP3_13725.1
PSMD3	huMAP3_05064.1 huMAP3_09656.1 huMAP3_13725.1
ADRM1	huMAP3_05064.1 huMAP3_09656.1 huMAP3_13725.1
PSMD4	huMAP3_05064.1 huMAP3_09656.1 huMAP3_13725.1
TMEM31	huMAP3_02158.1 huMAP3_05064.1 huMAP3_05667.1 huMAP3_08012.1 huMAP3_09656.1 huMAP3_11071.1 huMAP3_13609.1 huMAP3_13725.1
PSMD7	huMAP3_05064.1 huMAP3_09656.1 huMAP3_13725.1
PSMD8	huMAP3_05064.1 huMAP3_09656.1 huMAP3_13725.1
PSMD13	huMAP3_05064.1 huMAP3_09656.1 huMAP3_13725.1
PSMC3	huMAP3_04498.1 huMAP3_05064.1 huMAP3_06844.1 huMAP3_09656.1 huMAP3_10605.1 huMAP3_12778.1 huMAP3_13725.1
CCDC74A	huMAP3_00246.1 huMAP3_05064.1 huMAP3_09656.1 huMAP3_13725.1
BAG1	huMAP3_02568.1 huMAP3_05064.1 huMAP3_06678.1 huMAP3_08786.1 huMAP3_09656.1 huMAP3_09852.1 huMAP3_10150.1 huMAP3_13593.1 huMAP3_14723.1
PSMD11	huMAP3_05064.1 huMAP3_09656.1 huMAP3_13725.1
STKLD1	huMAP3_04498.1 huMAP3_05064.1 huMAP3_06844.1 huMAP3_09656.1 huMAP3_10605.1 huMAP3_12445.1 huMAP3_12778.1 huMAP3_13725.1
PSMD2	huMAP3_05064.1 huMAP3_09656.1 huMAP3_13725.1
PSMC1	huMAP3_03770.1 huMAP3_05064.1 huMAP3_08657.1 huMAP3_09656.1 huMAP3_10989.1 huMAP3_13725.1
PSMD1	huMAP3_05064.1 huMAP3_09656.1 huMAP3_13725.1
PAAF1	huMAP3_05064.1 huMAP3_09656.1 huMAP3_13725.1
CCDC74B	huMAP3_05064.1 huMAP3_09656.1 huMAP3_13725.1
PSMD6	huMAP3_05064.1 huMAP3_09656.1 huMAP3_13725.1
PSMD12	huMAP3_05064.1 huMAP3_09656.1 huMAP3_12445.1 huMAP3_13725.1
PSMD14	huMAP3_05064.1 huMAP3_09656.1 huMAP3_13725.1
CCDC92	huMAP3_05064.1 huMAP3_09656.1 huMAP3_13725.1
REX1BD	huMAP3_05064.1 huMAP3_09656.1 huMAP3_13725.1

hu.MAP 3.0: Complex View

Search for a protein

Complex: huMAP3_05064.1

Complex Portal: CPX-18578