hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_05065.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| ZNF253 | Zinc finger protein 253 (Bone marrow zinc finger 1) (BMZF-1) (Zinc finger protein 411) | 4 | UniProt NCBI |
| PGBD2 | PiggyBac transposable element-derived protein 2 | 2 | UniProt NCBI |
| FAXC | Failed axon connections homolog | 3 | UniProt NCBI |
| MAU2 | MAU2 chromatid cohesion factor homolog (MAU-2) (Cohesin loading complex subunit SCC4 homolog) | 5 | UniProt NCBI |
| TEX2 | Testis-expressed protein 2 (Transmembrane protein 96) | 4 | UniProt NCBI |
| NIPBL | Nipped-B-like protein (Delangin) (SCC2 homolog) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-2470946 | 0.00116019984728 | 0.333333333333 | MAU2 NIPBL | Cohesin Loading onto Chromatin |
| REAC:R-HSA-68884 | 0.00200991204249 | 0.333333333333 | MAU2 NIPBL | Mitotic Telophase/Cytokinesis |
| WP:WP5117 | 0.0046606239013 | 0.333333333333 | MAU2 NIPBL | Cohesin complex Cornelia de Lange syndrome |
| GO:0032116 | 0.00702301080125 | 0.333333333333 | MAU2 NIPBL | SMC loading complex |
| GO:0090694 | 0.00702301080125 | 0.333333333333 | MAU2 NIPBL | Scc2-Scc4 cohesin loading complex |
| GO:0061775 | 0.0210651876021 | 0.333333333333 | MAU2 NIPBL | cohesin loader activity |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| FAXC | PGBD2 | 0.999 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| FAXC | TEX2 | 0.998 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| NIPBL | MAU2 | 0.978 | 0.324 | hein_WMM bioplex_WMM bioplex3_WMM hein () Malo fraction |
| FAXC | MAU2 | 0.975 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| FAXC | ZNF253 | 0.972 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| FAXC | NIPBL | 0.969 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| PGBD2 | TEX2 | 0.267 | bioplex3_WMM WMM_only | |
| PGBD2 | NIPBL | 0.25 | bioplex3_WMM WMM_only | |
| PGBD2 | ZNF253 | 0.095 | bioplex3_WMM WMM_only | |
| ZNF253 | NIPBL | 0.093 | bioplex3_WMM WMM_only | |
| MAU2 | TEX2 | 0.089 | 0.08 | bioplex3_WMM WMM_only |
| PGBD2 | MAU2 | 0.078 | bioplex3_WMM WMM_only | |
| ZNF253 | TEX2 | 0.076 | bioplex3_WMM WMM_only | |
| ZNF253 | MAU2 | 0.076 | bioplex3_WMM WMM_only | |
| NIPBL | TEX2 | 0.058 | 0.09 | bioplex3_WMM youn_WMM WMM_only |
Related Complexes