hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_05071.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| PSEN1 | Presenilin-1 (PS-1) (EC 3.4.23.-) (Protein S182) [Cleaved into: Presenilin-1 NTF subunit; Presenilin-1 CTF subunit; Presenilin-1 CTF12 (PS1-CTF12)] | 5 | UniProt NCBI |
| ST3GAL1 | CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 (Alpha 2,3-ST 1) (Beta-galactoside alpha-2,3-sialyltransferase 1) (EC 2.4.3.4) (Gal-NAc6S) (Gal-beta-1,3-GalNAc-alpha-2,3-sialyltransferase) (Monosialoganglioside sialyltransferase) (EC 2.4.3.2) (SIATFL) (ST3Gal I) (ST3GalI) (ST3GalA.1) (ST3O) (Sialyltransferase 4A) (SIAT4-A) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:00533 | 0.0284987925806 | 0.5 | ST3GAL1 | Glycosaminoglycan biosynthesis - keratan sulfate |
| KEGG:00603 | 0.0308726352593 | 0.5 | ST3GAL1 | Glycosphingolipid biosynthesis - globo and isoglobo series |
| KEGG:00604 | 0.0356198329076 | 0.5 | ST3GAL1 | Glycosphingolipid biosynthesis - ganglio series |
| CORUM:3128 | 0.0499419797295 | 0.5 | PSEN1 | Gamma-secretase complex (APH1B, PSEN1, PSENEN, NCSTN) |
| CORUM:7574 | 0.0499419797295 | 0.5 | PSEN1 | APP-PSEN1 complex |
| HP:0012322 | 0.0499436884913 | 0.5 | PSEN1 | Perifolliculitis |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| ST3GAL1 | PSEN1 | 0.956 | 0.102 | bioplex3_WMM bioplex3_HCT116 WMM_only |
Related Complexes