hu.MAP 3.0: Complex View

Genename	Protein Name	Uniprot Annotation Score	Links
SNTA1	Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 1) (TACIP1) (Syntrophin-1)	5	UniProt NCBI
DTNA	Dystrobrevin alpha (DTN-A) (Alpha-dystrobrevin) (Dystrophin-related protein 3)	5	UniProt NCBI
DTNB	Dystrobrevin beta (DTN-B) (Beta-dystrobrevin)	5	UniProt NCBI
SNTB1	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (BSYN2) (Syntrophin-2) (Tax interaction protein 43) (TIP-43)	5	UniProt NCBI

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
WP:WP5406	1.14358251355e-06	0.75	SNTA1 SNTB1 DTNA	13q12 12 copy number variation
KEGG:05416	8.49257304271e-06	0.75	SNTA1 SNTB1 DTNA	Viral myocarditis
KEGG:05412	1.71467161414e-05	0.75	SNTA1 SNTB1 DTNA	Arrhythmogenic right ventricular cardiomyopathy
KEGG:05410	2.40425716137e-05	0.75	SNTA1 SNTB1 DTNA	Hypertrophic cardiomyopathy
KEGG:05414	2.40425716137e-05	0.75	SNTA1 SNTB1 DTNA	Dilated cardiomyopathy
WP:WP5343	0.000140344895657	0.5	DTNA SNTB1	Abnormal calcium handling and its effects on muscle contraction in DMD
WP:WP5356	0.00405547408869	0.5	DTNA SNTB1	Affected pathways in Duchenne muscular dystrophy
HPA:0090913	0.00667424506412	0.5	SNTA1 DTNA	cerebellum; Bergmann glia - nucleus[High]
HPA:0090912	0.0120057579663	0.5	SNTA1 DTNA	cerebellum; Bergmann glia - nucleus[>=Medium]
HPA:0090911	0.0140098381943	0.5	SNTA1 DTNA	cerebellum; Bergmann glia - nucleus[>=Low]
HPA:0090973	0.023110745047	0.5	SNTA1 DTNA	cerebellum; granular cells - cytoplasm/membrane[High]
CORUM:7341	0.049938562206	0.25	DTNA	CTNNAL1-DNTA complex

Protein 1	Protein 2	Score	ProteomeHD	Interface Overlap	Evidence
DTNB	SNTB1	0.995	0.108		bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only
SNTA1	DTNB	0.995	0.09		bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only
DTNA	DTNB	0.984	0.06	mutually_exclusive (Q9UBT7)	bioplex_WMM bioplex3_WMM WMM_only
SNTA1	DTNA	0.982	0.056		bioplex_WMM bioplex3_WMM WMM_only
SNTA1	SNTB1	0.98	0.08		bioplex_WMM bioplex3_WMM WMM_only
DTNA	SNTB1	0.938	0.048		bioplex_WMM bioplex3_WMM WMM_only