hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_05103.1
Confidence: Extremely High  
ProteinsGenename | Protein Name | Uniprot Annotation Score | Links |
---|---|---|---|
WDR5 | WD repeat-containing protein 5 (BMP2-induced 3-kb gene protein) | 5 | UniProt   NCBI |
NCOA6 | Nuclear receptor coactivator 6 (Activating signal cointegrator 2) (ASC-2) (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Nuclear receptor-activating protein, 250 kDa) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Thyroid hormone receptor-binding protein) | 5 | UniProt   NCBI |
ATN1 | Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein) | 5 | UniProt   NCBI |
Enrichments
Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
---|---|---|---|---|
  CORUM:6461 | 0.000122991556209 | 0.666666666667 | NCOA6 WDR5 | MLL3 complex |
  CORUM:6467 | 0.000122991556209 | 0.666666666667 | NCOA6 WDR5 | MLL4 complex |
  CORUM:5195 | 0.0001537324292 | 0.666666666667 | NCOA6 WDR5 | PTIP-HMT complex |
  CORUM:3075 | 0.000225453649047 | 0.666666666667 | NCOA6 WDR5 | UTX-MLL2/3 complex |
  WP:WP5351 | 0.000459327445001 | 0.666666666667 | NCOA6 WDR5 | Kleefstra syndrome |
  REAC:R-HSA-9772755 | 0.00530917647079 | 0.666666666667 | NCOA6 WDR5 | Formation of WDR5-containing histone-modifying complexes |
  REAC:R-HSA-5619507 | 0.0377646799279 | 0.666666666667 | NCOA6 WDR5 | Activation of HOX genes during differentiation |
  REAC:R-HSA-5617472 | 0.0377646799279 | 0.666666666667 | NCOA6 WDR5 | Activation of anterior HOX genes in hindbrain development during early embryogenesis |
Edges
Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
---|---|---|---|---|
 ATN1 |  WDR5 | 0.994 | 0.142           | bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     bioplex3_HCT116     |
 NCOA6 |  WDR5 | 0.984 | 0.352           | bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     youn_WMM     |
 NCOA6 |  ATN1 | 0.417 | 0.296           | bioplex_WMM     bioplex3_WMM     youn_WMM     WMM_only     |
Related Complexes