hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_05119.1
Complex Portal: CPX-10679
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| PTGER3 | Prostaglandin E2 receptor EP3 subtype (PGE receptor EP3 subtype) (PGE2 receptor EP3 subtype) (PGE2-R) (Prostanoid EP3 receptor) | 5 | UniProt NCBI |
| PLCB1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 (EC 3.1.4.11) (PLC-154) (Phosphoinositide phospholipase C-beta-1) (Phospholipase C-I) (PLC-I) (Phospholipase C-beta-1) (PLC-beta-1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP5122 | 9.83221512175e-05 | 1.0 | PLCB1 PTGER3 | Prostaglandin and leukotriene metabolism in senescence |
| WP:WP5321 | 0.000127691105477 | 1.0 | PLCB1 PTGER3 | Prostaglandin and leukotriene metabolism in senescence |
| KEGG:04020 | 0.00239074992693 | 1.0 | PLCB1 PTGER3 | Calcium signaling pathway |
| KEGG:05163 | 0.00298087791786 | 1.0 | PLCB1 PTGER3 | Human cytomegalovirus infection |
| KEGG:05200 | 0.0161326036311 | 1.0 | PLCB1 PTGER3 | Pathways in cancer |
| REAC:R-HSA-418594 | 0.0293992459454 | 1.0 | PLCB1 PTGER3 | G alpha (i) signalling events |
| WP:WP3679 | 0.049750157242 | 0.5 | PLCB1 | Cell type dependent selectivity of CCK2R signaling |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| PLCB1 | PTGER3 | 0.99 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
Related Complexes