hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_05134.1
Complex Portal: CPX-13936
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| UTP14A | U3 small nucleolar RNA-associated protein 14 homolog A (Antigen NY-CO-16) (Serologically defined colon cancer antigen 16) | 5 | UniProt NCBI |
| UTP14C | U3 small nucleolar RNA-associated protein 14 homolog C | 5 | UniProt NCBI |
| PNO1 | RNA-binding protein PNO1 (Partner of NOB1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-6790901 | 1.51687690066e-05 | 1.0 | UTP14A PNO1 UTP14C | rRNA modification in the nucleus and cytosol |
| REAC:R-HSA-6791226 | 0.000446006322638 | 1.0 | UTP14A PNO1 UTP14C | Major pathway of rRNA processing in the nucleolus and cytosol |
| REAC:R-HSA-8868773 | 0.000525011397177 | 1.0 | UTP14A PNO1 UTP14C | rRNA processing in the nucleus and cytosol |
| REAC:R-HSA-72312 | 0.000612835252183 | 1.0 | UTP14A PNO1 UTP14C | rRNA processing |
| KEGG:03008 | 0.0019996401701 | 0.666666666667 | UTP14A UTP14C | Ribosome biogenesis in eukaryotes |
| GO:0032040 | 0.0057325992498 | 1.0 | UTP14A PNO1 UTP14C | small-subunit processome |
| GO:0030684 | 0.0169989253844 | 1.0 | UTP14A PNO1 UTP14C | preribosome |
| REAC:R-HSA-8953854 | 0.0247774527734 | 1.0 | UTP14A PNO1 UTP14C | Metabolism of RNA |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| UTP14A | PNO1 | 0.983 | 0.698 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM |
| UTP14C | PNO1 | 0.975 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM | |
| UTP14A | UTP14C | 0.904 |
mutually_exclusive (Q9NRX1)
|
bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM WMM_only |
Related Complexes