hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_05135.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| CBLIF | Cobalamin binding intrinsic factor (Gastric intrinsic factor) (Intrinsic factor) (IF) (INF) | 5 | UniProt NCBI |
| TSHB | Thyrotropin subunit beta (Thyroid-stimulating hormone subunit beta) (TSH-B) (TSH-beta) (Thyrotropin beta chain) (Thyrotropin alfa) | 5 | UniProt NCBI |
| LRIF1 | Ligand-dependent nuclear receptor-interacting factor 1 (HP1-binding protein enriched in inactive X chromosome protein 1) (HBiX1) (Receptor-interacting factor 1) | 5 | UniProt NCBI |
| SMCHD1 | Structural maintenance of chromosomes flexible hinge domain-containing protein 1 (SMC hinge domain-containing protein 1) (EC 3.6.1.-) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0010984 | 0.00260592941411 | 0.5 | LRIF1 SMCHD1 | Digenic inheritance |
| GO:0001740 | 0.0168521501606 | 0.5 | LRIF1 SMCHD1 | Barr body |
| GO:0000805 | 0.042122686785 | 0.5 | LRIF1 SMCHD1 | X chromosome |
| CORUM:6479 | 0.049938562206 | 0.25 | CBLIF | Cubilin-intrinsic factor-cobalamin complex |
| REAC:R-HSA-3359457 | 0.0499436884912 | 0.25 | CBLIF | Defective CBLIF causes IFD |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| LRIF1 | SMCHD1 | 0.978 | 0.1 | hein_WMM bioplex3_WMM hein () gupta_WMM |
| TSHB | SMCHD1 | 0.965 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| CBLIF | SMCHD1 | 0.958 | bioplex3_WMM bioplex3_HCT116 WMM_only |
Related Complexes
| Genename | Complexes |
|---|---|
| CBLIF | huMAP3_02918.1 huMAP3_05135.1 huMAP3_08433.1 |
| TSHB | huMAP3_00524.1 huMAP3_05135.1 huMAP3_11531.1 huMAP3_13089.1 huMAP3_13413.1 huMAP3_13478.1 huMAP3_14446.1 huMAP3_14467.1 huMAP3_15337.1 |
| LRIF1 | huMAP3_05135.1 huMAP3_12058.1 |
| SMCHD1 | huMAP3_05135.1 |