hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_05137.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| NUDT14 | Uridine diphosphate glucose pyrophosphatase NUDT14 (UDPG pyrophosphatase) (UGPPase) (EC 3.6.1.45) (Nucleoside diphosphate-linked moiety X motif 14) (Nudix motif 14) | 5 | UniProt NCBI |
| DNAJC2 | DnaJ homolog subfamily C member 2 (M-phase phosphoprotein 11) (Zuotin-related factor 1) [Cleaved into: DnaJ homolog subfamily C member 2, N-terminally processed] | 5 | UniProt NCBI |
| HSPA14 | Heat shock 70 kDa protein 14 (HSP70-like protein 1) (Heat shock protein HSP60) | 4 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0051083 | 0.00140460216025 | 0.666666666667 | DNAJC2 HSPA14 | 'de novo' cotranslational protein folding |
| REAC:R-HSA-3371453 | 0.0141416283812 | 0.666666666667 | DNAJC2 HSPA14 | Regulation of HSF1-mediated heat shock response |
| REAC:R-HSA-3371556 | 0.0242497192193 | 0.666666666667 | DNAJC2 HSPA14 | Cellular response to heat stress |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| HSPA14 | DNAJC2 | 1.0 | 0.94 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM hein () bioplex3_HCT116 fraction |
| NUDT14 | HSPA14 | 0.989 | 0.086 | bioplex3_WMM bioplex3_HCT116 WMM_only |
| NUDT14 | DNAJC2 | 0.885 | 0.094 | bioplex3_WMM WMM_only |
Related Complexes
| Genename | Complexes |
|---|---|
| NUDT14 | huMAP3_01404.1 huMAP3_05137.1 huMAP3_14194.1 |
| DNAJC2 | huMAP3_05137.1 huMAP3_14194.1 |
| HSPA14 | huMAP3_01404.1 huMAP3_05137.1 huMAP3_14194.1 |