hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_05156.1
Complex Portal: CPX-13353
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| IDE | Insulin-degrading enzyme (EC 3.4.24.56) (Abeta-degrading protease) (Insulin protease) (Insulinase) (Insulysin) | 5 | UniProt NCBI |
| KRT7 | Keratin, type II cytoskeletal 7 (Cytokeratin-7) (CK-7) (Keratin-7) (K7) (Sarcolectin) (Type-II keratin Kb7) | 5 | UniProt NCBI |
| NES | Nestin | 5 | UniProt NCBI |
| VIM | Vimentin | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0045104 | 0.00212425290779 | 1.0 | NES KRT7 VIM | intermediate filament cytoskeleton organization |
| GO:0045103 | 0.00225170808226 | 1.0 | NES KRT7 VIM | intermediate filament-based process |
| GO:0005882 | 0.00381702295119 | 1.0 | NES KRT7 VIM | intermediate filament |
| GO:0045111 | 0.0124731132503 | 1.0 | NES KRT7 VIM | intermediate filament cytoskeleton |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| NES | VIM | 0.994 | 0.532833333333 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM hein () treiber_WMM | |
| IDE | NES | 0.992 | 0.138 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM hein () | |
| IDE | VIM | 0.987 | 0.194610526316 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt boldt_WMM | |
| KRT7 | VIM | 0.964 | 0.402608695652 | hein_WMM bioplex3_HEK293 boldt_WMM WMM_only | |
| IDE | KRT7 | 0.232 | 0.058 | hein_WMM WMM_only boldt_WMM | |
| KRT7 | NES | 0.154 | 0.434 | hein_WMM hein () |
Related Complexes