hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_05163.1
Complex Portal: CPX-17551
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| AKAP12 | A-kinase anchor protein 12 (AKAP-12) (A-kinase anchor protein 250 kDa) (AKAP 250) (Gravin) (Myasthenia gravis autoantigen) | 5 | UniProt NCBI |
| HSPA12A | Heat shock 70 kDa protein 12A | 4 | UniProt NCBI |
| HSPA12B | Heat shock 70 kDa protein 12B | 4 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-3371453 | 0.0141416283812 | 0.666666666667 | HSPA12B HSPA12A | Regulation of HSF1-mediated heat shock response |
| REAC:R-HSA-3371556 | 0.0242497192193 | 0.666666666667 | HSPA12B HSPA12A | Cellular response to heat stress |
| CORUM:518 | 0.0499402709677 | 0.333333333333 | AKAP12 | AKAP250-PKA-PDE4D complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| HSPA12B | HSPA12A | 0.999 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | |
| AKAP12 | HSPA12A | 0.998 | 0.168 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 gupta_WMM WMM_only |
| HSPA12B | AKAP12 | 0.916 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes