hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_05168.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| NME4 | Nucleoside diphosphate kinase, mitochondrial (NDK) (NDP kinase, mitochondrial) (EC 2.7.4.6) (Nucleoside diphosphate kinase D) (NDPKD) (nm23-H4) | 5 | UniProt NCBI |
| NME2 | Nucleoside diphosphate kinase B (NDK B) (NDP kinase B) (EC 2.7.4.6) (C-myc purine-binding transcription factor PUF) (Histidine protein kinase NDKB) (EC 2.7.13.3) (nm23-H2) | 5 | UniProt NCBI |
| NME1 | Nucleoside diphosphate kinase A (NDK A) (NDP kinase A) (EC 2.7.4.6) (Granzyme A-activated DNase) (GAAD) (Metastasis inhibition factor nm23) (NM23-H1) (Tumor metastatic process-associated protein) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:00240 | 0.000160943997529 | 1.0 | NME2 NME4 | Pyrimidine metabolism |
| KEGG:00983 | 0.000359441594481 | 1.0 | NME2 NME4 | Drug metabolism - other enzymes |
| KEGG:01232 | 0.000392605812153 | 1.0 | NME2 NME4 | Nucleotide metabolism |
| REAC:R-HSA-499943 | 0.000432316723289 | 1.0 | NME2 NME4 | Interconversion of nucleotide di- and triphosphates |
| KEGG:00230 | 0.000772693757832 | 1.0 | NME2 NME4 | Purine metabolism |
| KEGG:01240 | 0.00144865854745 | 1.0 | NME2 NME4 | Biosynthesis of cofactors |
| REAC:R-HSA-15869 | 0.00499983688673 | 1.0 | NME2 NME4 | Metabolism of nucleotides |
| GO:0004550 | 0.0257510396046 | 1.0 | NME2 NME4 | nucleoside diphosphate kinase activity |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| NME2 | NME1 | 0.996 | 0.94 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 gupta_WMM boldt_WMM treiber_WMM WMM_only |
| NME1 | NME4 | 0.982 | 0.172 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM WMM_only |
| NME2 | NME4 | 0.914 | 0.124 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes