hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_05174.1

Confidence: Extremely High

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Genename	Protein Name	Uniprot Annotation Score	Links
CCNH	Cyclin-H (MO15-associated protein) (p34) (p37)	5	UniProt NCBI
CDK7	Cyclin-dependent kinase 7 (EC 2.7.11.22) (EC 2.7.11.23) (39 kDa protein kinase) (p39 Mo15) (CDK-activating kinase 1) (Cell division protein kinase 7) (Serine/threonine-protein kinase 1) (TFIIH basal transcription factor complex kinase subunit)	5	UniProt NCBI
ERCC2	General transcription and DNA repair factor IIH helicase subunit XPD (TFIIH subunit XPD) (EC 3.6.4.12) (Basic transcription factor 2 80 kDa subunit) (BTF2 p80) (CXPD) (DNA excision repair protein ERCC-2) (DNA repair protein complementing XP-D cells) (TFIIH basal transcription factor complex 80 kDa subunit) (TFIIH 80 kDa subunit) (TFIIH p80) (Xeroderma pigmentosum group D-complementing protein)	5	UniProt NCBI
ERCC3	General transcription and DNA repair factor IIH helicase subunit XPB (TFIIH subunit XPB) (EC 3.6.4.12) (Basic transcription factor 2 89 kDa subunit) (BTF2 p89) (DNA excision repair protein ERCC-3) (DNA repair protein complementing XP-B cells) (TFIIH basal transcription factor complex 89 kDa subunit) (TFIIH 89 kDa subunit) (TFIIH p89) (Xeroderma pigmentosum group B-complementing protein)	5	UniProt NCBI
GTF2H1	General transcription factor IIH subunit 1 (Basic transcription factor 2 62 kDa subunit) (BTF2 p62) (General transcription factor IIH polypeptide 1) (TFIIH basal transcription factor complex p62 subunit)	5	UniProt NCBI
GTF2H2	General transcription factor IIH subunit 2 (Basic transcription factor 2 44 kDa subunit) (BTF2 p44) (General transcription factor IIH polypeptide 2) (TFIIH basal transcription factor complex p44 subunit)	5	UniProt NCBI
GTF2H2C	General transcription factor IIH subunit 2-like protein (General transcription factor IIH polypeptide 2-like protein)	4	UniProt NCBI
GTF2H3	General transcription factor IIH subunit 3 (Basic transcription factor 2 34 kDa subunit) (BTF2 p34) (General transcription factor IIH polypeptide 3) (TFIIH basal transcription factor complex p34 subunit)	5	UniProt NCBI
GTF2H4	General transcription factor IIH subunit 4 (Basic transcription factor 2 52 kDa subunit) (BTF2 p52) (General transcription factor IIH polypeptide 4) (TFIIH basal transcription factor complex p52 subunit)	5	UniProt NCBI
GTF2H5	General transcription factor IIH subunit 5 (General transcription factor IIH polypeptide 5) (TFB5 ortholog) (TFIIH basal transcription factor complex TTD-A subunit) (TFIIH subunit p8)	5	UniProt NCBI

Showing 1 to 10 of 11 entries

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Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
GO:0005675	3.69959944008e-33	1.0	GTF2H4 GTF2H1 CCNH GTF2H3 GTF2H5 CDK7 GTF2H2C GTF2H2 MNAT1 ERCC3 ERCC2	transcription factor TFIIH holo complex
CORUM:1009	5.97970892236e-33	0.909090909091	GTF2H4 GTF2H1 CCNH GTF2H3 GTF2H5 CDK7 GTF2H2 MNAT1 ERCC3 ERCC2	TFIIH transcription factor complex
CORUM:1029	5.97970892236e-33	0.909090909091	GTF2H4 GTF2H1 CCNH GTF2H3 GTF2H5 CDK7 GTF2H2 MNAT1 ERCC3 ERCC2	TFIIH transcription factor complex
GO:0000439	4.50272081853e-30	0.909090909091	GTF2H4 GTF2H1 CCNH GTF2H3 GTF2H5 CDK7 GTF2H2 MNAT1 ERCC3 ERCC2	transcription factor TFIIH core complex
CORUM:107	4.366981426e-29	0.818181818182	GTF2H4 GTF2H1 CCNH GTF2H3 CDK7 GTF2H2 MNAT1 ERCC3 ERCC2	TFIIH transcription factor complex
CORUM:1036	4.366981426e-29	0.818181818182	GTF2H4 GTF2H1 CCNH GTF2H3 CDK7 GTF2H2 MNAT1 ERCC3 ERCC2	TFIIH transcription factor complex
GO:0032806	5.1782060163e-29	1.0	GTF2H4 GTF2H1 CCNH GTF2H3 GTF2H5 CDK7 GTF2H2C GTF2H2 MNAT1 ERCC3 ERCC2	carboxy-terminal domain protein kinase complex
REAC:R-HSA-77075	1.23800207354e-25	0.909090909091	GTF2H4 GTF2H1 CCNH GTF2H3 GTF2H5 CDK7 GTF2H2 MNAT1 ERCC3 ERCC2	RNA Pol II CTD phosphorylation and interaction with CE
REAC:R-HSA-167160	1.23800207354e-25	0.909090909091	GTF2H4 GTF2H1 CCNH GTF2H3 GTF2H5 CDK7 GTF2H2 MNAT1 ERCC3 ERCC2	RNA Pol II CTD phosphorylation and interaction with CE during HIV infection
REAC:R-HSA-72086	3.05821221316e-25	0.909090909091	GTF2H4 GTF2H1 CCNH GTF2H3 GTF2H5 CDK7 GTF2H2 MNAT1 ERCC3 ERCC2	mRNA Capping

Showing 1 to 10 of 181 entries

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Protein 1	Protein 2	Score	ProteomeHD
GTF2H4	ERCC3	1.0	0.256
GTF2H2	GTF2H1	1.0	0.404
CDK7	CCNH	1.0	0.344
GTF2H2	GTF2H3	1.0	0.648
GTF2H2	ERCC3	1.0	0.286
GTF2H4	GTF2H1	1.0	0.162
CCNH	MNAT1	1.0	0.476
GTF2H1	GTF2H3	1.0	0.354
CDK7	MNAT1	1.0	0.376
GTF2H4	GTF2H3	1.0	0.402

Showing 1 to 10 of 54 entries

Related Complexes

Genename	Complexes
GTF2H2C	huMAP3_05174.1 huMAP3_09908.1 huMAP3_12429.1 huMAP3_15000.1
GTF2H2	huMAP3_05174.1 huMAP3_09908.1 huMAP3_12429.1
GTF2H4	huMAP3_05174.1 huMAP3_09908.1 huMAP3_12429.1
CDK7	huMAP3_05174.1 huMAP3_09908.1 huMAP3_12429.1
ERCC2	huMAP3_05174.1 huMAP3_09908.1 huMAP3_12429.1
GTF2H1	huMAP3_05174.1 huMAP3_09908.1 huMAP3_12429.1
ERCC3	huMAP3_05174.1 huMAP3_09908.1 huMAP3_12429.1
GTF2H5	huMAP3_05174.1 huMAP3_09908.1 huMAP3_12429.1
CCNH	huMAP3_05174.1 huMAP3_09908.1 huMAP3_12429.1 huMAP3_14722.1
GTF2H3	huMAP3_05174.1 huMAP3_09908.1 huMAP3_12429.1
MNAT1	huMAP3_05174.1 huMAP3_09908.1 huMAP3_12429.1