hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_05200.1
Confidence: Extremely High  
ProteinsGenename | Protein Name | Uniprot Annotation Score | Links |
---|---|---|---|
PTGES3 | Prostaglandin E synthase 3 (EC 5.3.99.3) (Cytosolic prostaglandin E2 synthase) (cPGES) (Hsp90 co-chaperone) (Progesterone receptor complex p23) (Telomerase-binding protein p23) | 5 | UniProt   NCBI |
FKBP4 | Peptidyl-prolyl cis-trans isomerase FKBP4 (PPIase FKBP4) (EC 5.2.1.8) (51 kDa FK506-binding protein) (FKBP51) (52 kDa FK506-binding protein) (52 kDa FKBP) (FKBP-52) (59 kDa immunophilin) (p59) (FK506-binding protein 4) (FKBP-4) (FKBP59) (HSP-binding immunophilin) (HBI) (Immunophilin FKBP52) (Rotamase) [Cleaved into: Peptidyl-prolyl cis-trans isomerase FKBP4, N-terminally processed] | 5 | UniProt   NCBI |
Enrichments
Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
---|---|---|---|---|
  REAC:R-HSA-3371568 | 0.000133283416666 | 1.0 | PTGES3 FKBP4 | Attenuation phase |
  REAC:R-HSA-3371571 | 0.000432316723289 | 1.0 | PTGES3 FKBP4 | HSF1-dependent transactivation |
  REAC:R-HSA-3371497 | 0.00226581808332 | 1.0 | PTGES3 FKBP4 | HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand |
  REAC:R-HSA-3371556 | 0.0061002794551 | 1.0 | PTGES3 FKBP4 | Cellular response to heat stress |
  REAC:R-HSA-9679191 | 0.0061002794551 | 1.0 | PTGES3 FKBP4 | Potential therapeutics for SARS |
  REAC:R-HSA-9018519 | 0.0136718027788 | 1.0 | PTGES3 FKBP4 | Estrogen-dependent gene expression |
  REAC:R-HSA-8939211 | 0.0290831250212 | 1.0 | PTGES3 FKBP4 | ESR-mediated signaling |
  CORUM:6591 | 0.0499419797295 | 0.5 | PTGES3 | Hsp90-p23 complex |
Edges
Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
---|---|---|---|---|
 FKBP4 |  PTGES3 | 0.981 | 0.498           | bioplex3_HEK293     bioplex_WMM     Guru     bioplex3_WMM     boldt     youn_WMM     bioplex3_HCT116     gupta_WMM     fraction     boldt_WMM     |
Related Complexes
Genename | Complexes |
---|---|
PTGES3 | huMAP3_05200.1 huMAP3_11552.1 huMAP3_11721.1 huMAP3_13837.1 |
FKBP4 | huMAP3_01466.1 huMAP3_05200.1 huMAP3_06313.1 huMAP3_07524.1 huMAP3_11169.1 huMAP3_11710.1 huMAP3_12466.1 |