hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_05200.1

Complex Portal: CPX-22307

Confidence: Extremely High

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Genename	Protein Name	Uniprot Annotation Score	Links
FKBP4	Peptidyl-prolyl cis-trans isomerase FKBP4 (PPIase FKBP4) (EC 5.2.1.8) (51 kDa FK506-binding protein) (FKBP51) (52 kDa FK506-binding protein) (52 kDa FKBP) (FKBP-52) (59 kDa immunophilin) (p59) (FK506-binding protein 4) (FKBP-4) (FKBP59) (HSP-binding immunophilin) (HBI) (Immunophilin FKBP52) (Rotamase) [Cleaved into: Peptidyl-prolyl cis-trans isomerase FKBP4, N-terminally processed]	5	UniProt NCBI
PTGES3	Prostaglandin E synthase 3 (EC 5.3.99.3) (Cytosolic prostaglandin E2 synthase) (cPGES) (Hsp90 co-chaperone) (Progesterone receptor complex p23) (Telomerase-binding protein p23)	5	UniProt NCBI

Showing 1 to 2 of 2 entries

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Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
REAC:R-HSA-3371568	0.000133283416666	1.0	PTGES3 FKBP4	Attenuation phase
REAC:R-HSA-3371571	0.000432316723289	1.0	PTGES3 FKBP4	HSF1-dependent transactivation
REAC:R-HSA-3371497	0.00226581808332	1.0	PTGES3 FKBP4	HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand
REAC:R-HSA-3371556	0.0061002794551	1.0	PTGES3 FKBP4	Cellular response to heat stress
REAC:R-HSA-9679191	0.0061002794551	1.0	PTGES3 FKBP4	Potential therapeutics for SARS
REAC:R-HSA-9018519	0.0136718027788	1.0	PTGES3 FKBP4	Estrogen-dependent gene expression
REAC:R-HSA-8939211	0.0290831250212	1.0	PTGES3 FKBP4	ESR-mediated signaling
CORUM:6591	0.0499419797295	0.5	PTGES3	Hsp90-p23 complex

Showing 1 to 8 of 8 entries

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Protein 1	Protein 2	Score	ProteomeHD	Interface Overlap	Evidence
FKBP4	PTGES3	0.981	0.498		bioplex3_HEK293 bioplex_WMM Guru bioplex3_WMM boldt youn_WMM bioplex3_HCT116 gupta_WMM fraction boldt_WMM

Showing 1 to 1 of 1 entries

Related Complexes

Genename	Complexes
PTGES3	huMAP3_05200.1 huMAP3_11552.1 huMAP3_11721.1 huMAP3_13837.1
FKBP4	huMAP3_01466.1 huMAP3_05200.1 huMAP3_06313.1 huMAP3_07524.1 huMAP3_11169.1 huMAP3_11710.1 huMAP3_12466.1